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    This is an extremely potent opioid active in microgram doses. Accidental overdose can be rapidly fatal. Naloxone should always be on hand.

    Carfentanil Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present

    Aliases: Carfentanyl, Wildnil, R-33799, 4-methoxycarbonylfentanyl

    Summary TheDrug.Wiki

    Carfentanil is an ultra-potent synthetic opioid of the 4-anilidopiperidine class, estimated at roughly 10,000x the potency of morphine and ~100x that of fentanyl. It has NO recognised human therapeutic or recreational dose — it is used in veterinary medicine to immobilise large animals (brand name Wildnil). Microgram-level exposure can cause fatal respiratory depression. Carfentanil is increasingly found as an adulterant or substitute in the illicit opioid supply (often pressed into counterfeit pills or mixed into heroin/fentanyl), so exposure is frequently unintentional. Treat any suspected exposure as a medical emergency: give naloxone (repeated/large doses are often required), call emergency services, and monitor for prolonged or recurrent respiratory depression.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset
    Oral Seconds to minutes Minutes -
    Insufflated Seconds to minutes Minutes -

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 2.6
    Light+ 3/10

    Moderate sedation and itching/nausea with mild pain relief

    Euphoria / Warmth ×3
    0
    Analgesia ×2
    4
    analgesia
    Sedation / Relaxation ×1
    7
    profound sedation sedation
    Itching / Nausea ×1
    7
    nausea vomiting

    Tolerance

    Cross-Tolerances

    Effects TheDrug.Wiki

    Positive
    • Analgesia
    Negative
    • Respiratory depression
    • Unconsciousness
    • Nausea
    • Vomiting
    Neutral
    • Profound sedation
    • Pinpoint pupils
    Neutral
    • Sedation

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