I am a recreational opiate user as well as for chronic pain. First of let me say I have a moderate to heavy tolerance for opiates so if you are not used to taking opiate based medications this guide is probably not for you although you could apply its information to find a dosage that fits you.
Fentanyl
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
Aliases: Tnt, Fent, Fenty, Fetty, Actiq
Summary
Fentanyl (also known as Fentanil and by the brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda among others) is a potent opioid substance of the anilidopiperidine class. It is a strong agonist at the μ-opioid receptors and approximately 40 to 50 times more potent than pharmaceutical grade (i.e. 100% pure) heroin and roughly 80 to 100 times more potent than morphine.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-25μg | 25-50μg | 50-75μg | 75ug+ |
| Transdermal | 12-25μg | 25-50μg | 50-100μg | 100μg+ |
| Sublingual | 10-25μg | 25-50μg | 50-75μg | 75μg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-30 min | 30-90 min | 1-2 hrs | - |
| Insufflated | 15-30 min | 30-60 min | 30-90 min | 1-4 hrs |
| Transdermal | 2-4 hrs | 12-24 hrs | 12-24 hrs | 48-72 hrs |
| Sublingual | 12-30 min | 30-90 min | 30-90 min | 1-4 hrs |
Opioid MME Calculator
⚠ Citation & Disclaimer:
Conversion factors sourced from the
NIH HEAL Initiative MME Calculator (Adams et al., PAIN 2025),
the CDC 2022 Clinical Practice Guideline for Prescribing Opioids for Pain,
and the MDCalc MME Calculator.
These are approximate equianalgesic ratios for educational reference only.
Individual responses vary significantly based on genetics, tolerance, cross-tolerance, and route of administration.
This is not medical advice. Do not use these conversions to adjust opioid dosing without professional medical guidance.
mg
0.077
mg
Fentanyl
≈
—
mg
Morphine
| Substance | Equivalent Dose | MME Factor |
|---|
⚠ Equianalgesic dose ratios are approximations and do not account for genetic factors, tolerance, incomplete cross-tolerance, or pharmacokinetic variations. Methadone conversion is especially variable at higher doses. Always consult a healthcare provider before making any changes to opioid therapy.
Effect Profile
128 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 108 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
7.6
Intense
8/10
Strong pain relief and sedation with moderate euphoria and itching/nausea
Euphoria / Warmth
×3
7
physical euphoria
cognitive euphoria
euphoria
“I felt as if there was alot of pressure in my head but it felt great, I was a little nervous of nodding and never waking up but effects subsided about 30 minutes later.”
“No real euphoria present, as is typical with Fentanyl itself, so this wasn't suprising.”
Analgesia
×2
10
pain relief
analgesia
“Carfentanyl is stronger hypnosedative under analgesic equivalent doses as fentanyl.”
“I would attempt to get it turned into powder to smoke...or I would just use it as directed bc I didn't get any high out of slamming it so I think if I had just put it on my skin at least I wouldn't...”
Sedation / Relaxation
×1
8
sedation
drowsiness
dream potentiation
“(Cheap, good painkiller, not making me too tired (stimulating me!), easy to have a lifelong supply if you can control their usage a little, not being organotoxic at all, etc..).”
“I have had these patches for a long time using 3/4 of one without any effects until now 10 minutes/ The feeling was intense no euphoria what so ever but a deep relaxed state i fell into.”
Itching / Nausea
×1
6
nausea
constipation
dry mouth
sweating
“I think it's called precipitated withdrawals, but that felt worse than slamming H after slamming the Fent patch, you feel instantly nauseous & goose bumps galore & sometimes a headache, instant body...”
“My friends were really sick , but only my for the longest 2 days of their life's.”
User Experience
pain relief
“Carfentanyl is stronger hypnosedative under analgesic equivalent doses as fentanyl.”
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Tolerance Decay
Half tolerance
7d
Baseline
~14d
Cross-tolerance
Effects
Aggregated from 108 Erowid and 20 Bluelight experience reports
Positive Effects 29
Euphoria
44.5%
93%
Sedation
35.2%
89%
Contentment
35.0%
84%
Empathy
23.4%
85%
Anxiety Suppression
20.3%
80%
Thought Deceleration
20.0%
84%
Stimulation
19.5%
80%
Tactile Enhancement
16.7%
70%
Pain Relief
16.4%
88%
Body High
15.7%
89%
Peace
15.0%
87%
Sociability Enhancement
15.0%
89%
Focus Enhancement
13.0%
70%
Music Enhancement
10.2%
70%
Color Enhancement
10.2%
70%
Heaviness
10.0%
85%
Love
10.0%
88%
Warmth
10.0%
90%
Joy
10.0%
85%
Drowsiness
5.0%
85%
Adverse Effects 27
Nausea
31.3%
88%
Vomiting
20.0%
91%
Confusion
10.2%
70%
Numbness
10.0%
88%
Insomnia
10.0%
92%
Body Load
10.0%
80%
Hot Flashes
10.0%
85%
Headache
7.0%
78%
Motor Impairment
6.2%
86%
Increased Heart Rate
5.6%
70%
Memory Suppression
5.6%
70%
Sweating
5.6%
70%
Respiratory Suppression
5.0%
95%
Fear
5.0%
95%
Panic
5.0%
90%
Dizziness
5.0%
88%
Eye Strain
5.0%
75%
Vibrating
5.0%
85%
Thought Disorganization
5.0%
88%
Emotional Blunting
5.0%
85%
Combinations
Cross-Check Fentanyl with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
This report would be much more useful to those with a considerably low tolerance to opiates. The first time I tried a Fentanyl Lollipop I liked it very much. My friend sold me the 800mcg kind, and I must say it tasted pretty good.
All the reports I've read here about fentanyl seem pretty negative or not very positive, so I'd like to share my experience with this drug. I got the gel patches for free a few months ago, 4 patches to be exact. I decided to be stupid and eat the gel inside.
So I was looking on the vault for some info on fentanyl which seems very hard to find anyway and saw that there were not a lot of experiences and I wanted to contribute mine. But I think a tiny history is necessary. First I have tried may drugs. Weed, shrooms, acid (once and like ½ a dose), just to name a few.
Date: '06 1 31 Substance: Fentanyl Citrate 100mcg / 2 mL (50mcg/mL) I have obtained a tiny ampule of fentanyl made by Abbott Labs. I paid ten dollars for it - a very good price. Sadly I did not get a sterile syringe so I must use the drug in a different way. But first let me describe myself and my background.
Background: I have experience with many drugs, but for the purposes of this experience report, Ill limit the discussion strictly to the opiates and other painkillers. Ive tried codeine, morphine, oxycodone, tramadol, hydrocodone, opium, and heroin.
Background: I have done a very large number of drugs since I first tried them when I was fifteen. I am very cautious and intelligent when it comes to the subject though. Drugs have always fascinated me so I learned about them and researched them thoroughly before I tried each one.
Fentanyl With No Tolerance A Horrible Idea I had been pining to get my hands on some opioids for quite some time, so when a very thoughtful boss at work one day gave me a present', a 25 ug/hr gel fentanyl patch, I didn't think twice to accept it.
Bluelight 8 threads 6 neutral 2 cautionary visit
Substance: Fentanyl (Actiq lollipop) Experience: very experienced Setting: My home November 3, 2005 It has been nearly two years since I wrote my last report. My life is quite different from what it was only two years ago. Being a full time student and still working thirty hours a week consumes most of my time.
I should begin this story with a bit of background. I am now 20, was 19 when this trip happened and am fairly experienced with opiates (all pharmaceutical, not H). I am 175-180 pounds, 6'1 athletic and in good shape. My tolerance is about 30 mg Oxy to get me off, 100 morphine for solid nod.
I was given a Fentanyl transdermal patch. The patch was square, tan on one side, metallic and shiny on the other side. I seem to recall the packaging saying "Teva." The patch is designed to deliver 25mcg per hour for 72 hours. A somewhat low dose, but I don't fool around with Fentanyl at all.
9:00 pm: I get two 25 ug/hr Duragesic patches and come straight home to my computer to decided on which route I would choose to administer them. After reading a lot of debate and controversy, despite popular belief, I decide to eat the gel of one patch, thats 2.5 mgs of Fentanyl.
I had only heard stories of fentanyl before yesterday. I was going to trade my old high school school friend bud for 8mg morphone pills because it was the weekend and I'd been clean two weeks except for the night before I got 5 pinkish morphine pills. I smoked four and gave one away.
Introduction and basics Well let's start with a bit of background first , I have been an opiate user for the last 9 years (yes i started as a minor with codeine/poppy's) , had a period as a homeless person (IV heroin/ Crack Cocaine), However I had abstained from all opiates for the last 2 years.
I guess the title pretty much explains it all... This is probably one of many little cautionary tales for anyone thinking of messing with the queen mother of opiates in any way other than what the instructions on the label indicate that don't know preCISEly what they're doing...
Yes, well. A 25ug/h Durogesic patch became available and naturally an opiate sucker has difficulties staying away. This might not be a complete trip report since I think I still have not experienced a perfect dose but I dont have anything to do now so...
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