Fentanyl
Aliases: Tnt, Fent, Fenty, Fetty, Actiq
Summary
Fentanyl (also known as Fentanil and by the brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda among others) is a potent opioid substance of the anilidopiperidine class. It is a strong agonist at the μ-opioid receptors and approximately 40 to 50 times more potent than pharmaceutical grade (i.e. 100% pure) heroin and roughly 80 to 100 times more potent than morphine.[citation needed].
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-25μg | 25-50μg | 50-75μg | 75ug+ |
| Transdermal | 12-25μg | 25-50μg | 50-100μg | 100μg+ |
| Sublingual | 10-25μg | 25-50μg | 50-75μg | 75μg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-30 min | 30-90 min | 1-2 hrs | - |
| Insufflated | 15-30 min | 30-60 min | 30-90 min | 1.2-3 hrs |
| Transdermal | 2-4 hrs | 12-24 hrs | 12-24 hrs | 26-52 hrs |
| Sublingual | 12-30 min | 30-90 min | 30-90 min | 1.2-3.5 hrs |
Opioid MME Calculator
| Substance | Equivalent Dose | MME Factor |
|---|
⚠ Equianalgesic dose ratios are approximations and do not account for genetic factors, tolerance, incomplete cross-tolerance, or pharmacokinetic variations. Methadone conversion is especially variable at higher doses. Always consult a healthcare provider before making any changes to opioid therapy.
Effect Profile
128 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 108 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong pain relief and sedation with moderate euphoria and itching/nausea
“I felt as if there was alot of pressure in my head but it felt great, I was a little nervous of nodding and never waking up but effects subsided about 30 minutes later.”
“No real euphoria present, as is typical with Fentanyl itself, so this wasn't suprising.”
“Carfentanyl is stronger hypnosedative under analgesic equivalent doses as fentanyl.”
“I would attempt to get it turned into powder to smoke...or I would just use it as directed bc I didn't get any high out of slamming it so I think if I had just put it on my skin at least I wouldn't...”
“(Cheap, good painkiller, not making me too tired (stimulating me!), easy to have a lifelong supply if you can control their usage a little, not being organotoxic at all, etc..).”
“I have had these patches for a long time using 3/4 of one without any effects until now 10 minutes/ The feeling was intense no euphoria what so ever but a deep relaxed state i fell into.”
“I think it's called precipitated withdrawals, but that felt worse than slamming H after slamming the Fent patch, you feel instantly nauseous & goose bumps galore & sometimes a headache, instant body...”
“My friends were really sick , but only my for the longest 2 days of their life's.”
User Experience
Tolerance
Tolerance Decay
Fentanyl tolerance decays significantly within 1–2 weeks of abstinence. Tolerance to analgesic effects is lost faster than tolerance to respiratory depression, creating a dangerous window where returning to a previous dose can cause fatal overdose. Even brief periods of abstinence (3–5 days) substantially reduce tolerance. Sources: StatPearls Fentanyl (NBK459275), PCSS Opioid Tolerance, American Addiction Centers.
Effects
Aggregated from 108 Erowid and 20 Bluelight experience reports