Settings : I'm with a group of friends and others that I don't know, our camp is situated in a small forest next to a big lake. 10 am - Like every day in this period we are taking the breakfast with big lines of ketamine when one of my friend says he has some new stuff to try.
Desoxypipradrol
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Pippy, 2-dpmp, Ivory wave, Vanillasky, Purple wave, 2dpmp, 2-desoxypiperadol, desoxypipradol
Summary
Desoxypipradrol is an extremely potent and long-lasting stimulant with an unusually high elimination half-life of 16-24 hours. Originally developed by Ciba (Novartis) in the 1950s for narcolepsy and ADHD but abandoned in favor of methylphenidate due to its excessive duration and unpredictable pharmacokinetics. The drug's high lipophilicity and lack of polar functional groups make it resistant to metabolic breakdown, resulting in effects that can persist for 24-72+ hours.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-2mg | 2-6mg | 6-8mg | 8mg+ |
| Insufflated | 0.5-1.5mg | 1.5-3.5mg | 3.5-5mg | 5mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 4-12 hrs | 12-36 hrs | 16-72 hrs |
| Insufflated | 5-20 min | 30-90 min | 4-12 hrs | 12-36 hrs | 16-72 hrs |
Effect Profile
5 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
5.9
Strong
6/10
Strong anxiety/jitters and euphoria with moderate focus, mild stimulation
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
9
cognitive euphoria
euphoria
mood lift
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
paranoia
increased heart rate
teeth grinding
bruxism
vasoconstriction
+1 more
Based on reports from:
Import into PsychonautWiki Journal
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Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Tolerance Decay
Full tolerance
1d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal pattern: functional ‘benefit’ tolerance builds across consecutive days while adverse effects increase; several days to weeks are needed for baseline reset. Data are low quality and user‑reported, not from controlled PK/PD studies.
Cross-Tolerances
Amphetamines
30%
Effects
Aggregated from 5 Erowid experience reports
Positive Effects 2
Stimulation
100.0%
70%
Focus Enhancement
60.0%
70%
Adverse Effects 0
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 4 reports 1 neutral 3 cautionary visit
I just happened to have procured 2 grams of this material [2-DPMP) mainly just out of curiousity. I am a 22 year old male, very expierenced with drugs in general (stimulants like e, mdma, coke, amphetamine. Psychedelics lsd mushrooms morning glory.
hi I am a 22 year old male who has much expierence with this drug, as well as most any drug with the exception of some of the new designer drugs. Anyhow I'll just give a brief description of effects if snorted.
Was interested in finding stimulants to help with studying and wakefulness. Saw this was structurally similar to methylphenidate and obtained 250 mg to test it. Dissolved it in 500 mL of water to make a 0.5 mg/mL solution to dose volumetrically with a (needleless) syringe.
Bluelight 5 threads 4 neutral 1 cautionary visit
So I had some 2dpmp sitting in a little baggie and I also had some pure synthetic mesembrine (not plant extract, this was custom synthed stuff). I had enjoyed smoking each substance by them selves previuosly so I decided to mix up about 5mg of each and see how well they worked together.
I've decided to put a few of my initial impressions of this 'designer stimulant' into the written word form just in case (as I seriously expect) it becomes 'the next big thing' among stimulants, much like what happened with the appearance of MDPV.
Hi guys judgefooky here again excuse the SWIM(SOMEONE WHO ISnt ME!) AND FoF references (FRIEND OF FRIEND) couldn't be bothered to change my post from DF (edwardstedward) 20/08/10 This is a comparison trip report on IVORY WAVE 'Bath Salts' in UK headshops right now SWIM has taken Ivory Wave twice in the last 2 weeks.
Desoxypipradrol - First Experience(s) - 5mg+7mg - A Comparison Those who do not want to read the full report skip ahead to the red FIN sign for a conclusion and summary Route : Insufflation/Nasal Weight : 185lbs Resting Heart-Rate: 64BPM Tolerance to stimulants : None [Drugs taken in the past 7 days - cannabis (last ni...
Before I begin to explain my experience on 2-dpmp I seriously recommend you know what you're doing and understand the way it works and how it works. We are lucky no one died or got seriously injured and you'll find out why after reading sorry that it's long but it's worth the read when you get into it...
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