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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Desoxypipradrol

    Aliases: Pippy, 2-dpmp, Ivory wave, Vanillasky, Purple wave, 2dpmp, 2-desoxypiperadol, desoxypipradol

    Categories

    Stimulant Research-chemical
    Desoxypipradrol structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Desoxypipradrol is an extremely potent and long-lasting stimulant with an unusually high elimination half-life of 16-24 hours. Originally developed by Ciba (Novartis) in the 1950s for narcolepsy and ADHD but abandoned in favor of methylphenidate due to its excessive duration and unpredictable pharmacokinetics. The drug's high lipophilicity and lack of polar functional groups make it resistant to metabolic breakdown, resulting in effects that can persist for 24-72+ hours. Users report an increased risk of compulsive redosing due to the subtle and gradual onset of effects, which can lead to severe and prolonged agitation, psychosis, insomnia, and cardiovascular complications lasting up to 5-7 days. Use extreme caution with dosing and avoid redosing entirely.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 1-2mg 2-6mg 6-8mg 8mg+
    Insufflated 0.5-1.5mg 1.5-3.5mg 3.5-5mg 5mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-90 min 1-2 hrs 4-12 hrs 12-36 hrs 24-72 hrs 960-0 min
    Insufflated 5-20 min 30-90 min 4-12 hrs 12-36 hrs 24-72 hrs 960-0 min

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Effects TheDrug.Wiki TripSit

    Positive
    • Stimulation
    • Increased energy/alertness
    Negative
    • Increased heart rate
    • Insomnia
    • Vasoconstriction
    • Increased perspiration
    • Teeth grinding
    • Weight loss
    • Sweating
    • Bruxism
    Neutral
    • Decreased need for sleep
    • Decreased appetite
    • Disturbed sleep patterns
    • Itchiness
    Positive
    • Focus enhancement
    • Cognitive euphoria
    • Wakefulness
    • Motivation enhancement
    • Euphoria
    • Increased sociability
    • Mood lift
    Negative
    • Compulsive redosing
    • Anxiety
    • Paranoia
    • Psychosis
    • Delirium
    • Mania
    • Agitation
    • Depersonalization
    • Derealization
    • Aggressiveness
    Neutral
    • Thought acceleration
    • Ego inflation
    • Excessive talking
    • Moodiness
    Positive
    • Tactile enhancement
    • Color enhancement
    • Increased music appreciation
    Negative
    • Appetite suppression
    • Light sensitivity
    • Disinhibition
    Neutral
    • Increased sexuality
    • Visual and auditory hallucinations
    • Dulled perception
    • Drifting

    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki