Desoxypipradrol
Aliases: Pippy, 2-dpmp, Ivory wave, Vanillasky, Purple wave, 2dpmp, 2-desoxypiperadol, desoxypipradol
Summary
Desoxypipradrol is an extremely potent and long-lasting stimulant with an unusually high elimination half-life of 16-24 hours. Originally developed by Ciba (Novartis) in the 1950s for narcolepsy and ADHD but abandoned in favor of methylphenidate due to its excessive duration and unpredictable pharmacokinetics. The drug's high lipophilicity and lack of polar functional groups make it resistant to metabolic breakdown, resulting in effects that can persist for 24-72+ hours.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-2mg | 2-6mg | 6-8mg | 8mg+ |
| Insufflated | 0.5-1.5mg | 1.5-3.5mg | 3.5-5mg | 5mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 4-12 hrs | 12-36 hrs | 17.5-51.5 hrs |
| Insufflated | 5-20 min | 30-90 min | 4-12 hrs | 12-36 hrs | 16.6-49.8 hrs |
Effect Profile
5 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters and euphoria with moderate focus, mild stimulation
Tolerance
Tolerance Decay
Anecdotal pattern: functional ‘benefit’ tolerance builds across consecutive days while adverse effects increase; several days to weeks are needed for baseline reset. Data are low quality and user‑reported, not from controlled PK/PD studies.
Cross-Tolerances
Effects
Aggregated from 5 Erowid experience reports