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    Deliriants can cause frightening, uncontrollable hallucinations and dangerous behavior. Medical emergencies are common at higher doses.

    Dimenhydrinate Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 3 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data

    Aliases: Dime, Drama, Drams, Gravol, Dimate, dramamine

    Summary TheDrug.Wiki Erowid TripSit

    Dimenhydrinate is commonly sold as Dramamine or Gravol for motion sickness treatment. It dissociates into diphenhydramine (53-55.5% by weight) and 8-chlorotheophylline in the body, with roughly half the potency of pure diphenhydramine. At recreational doses, it causes severe delirium, realistic hallucinations, profound confusion, and anticholinergic toxicity.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 100-250mg 250mg-400mg 400mg-600mg 600mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 30-60 min 2-4 hrs 2-4 hrs 24 hrs 5-8 hrs

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 3d Half tolerance 7d Baseline ~14d

    Anecdotal reports suggest rapid tolerance to deliriant/anticholinergic cognitive and hallucinatory effects with repeated dosing over days, with partial reversal over 1–2 weeks. Data quality low; avoid frequent use to reduce cumulative anticholinergic burden.

    Cross-Tolerances

    Effects Erowid

    Aggregated from 221 Erowid experience reports

    Positive Effects 11

    Anxiety Suppression 51.1% 70%
    Sedation 43.4% 70%
    Stimulation 29.9% 70%
    Music Enhancement 25.3% 70%
    Color Enhancement 25.3% 70%
    Tactile Enhancement 24.4% 70%
    Euphoria 15.8% 70%
    Focus Enhancement 15.8% 70%
    Empathy 12.2% 70%
    Body High 8.6% 70%
    Introspection 5.4% 70%

    Adverse Effects 11

    Confusion 33.9% 70%
    Memory Suppression 26.7% 70%
    Nausea 20.8% 70%
    Pupil Dilation 13.1% 70%
    Motor Impairment 12.7% 70%
    Headache 6.8% 70%
    Increased Heart Rate 5.4% 70%
    Sweating 5.0% 70%
    Psychosis 4.5% 70%
    Seizure 4.1% 70%
    Jaw Clenching 2.7% 70%

    Combinations TripSit

    Cross-Check Dimenhydrinate with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Fighting Writer's Block positive exp #110599

    My Background: I first started smoking marijuana in college, in March 2016. Prior to that, I had been intensely curious about psychedelics and the human mind, but had never really known much about where to find them. Instead, I simply meditated, wrote, and read books.

    villager24 · oral / 550 mg oral / oral
    I Enjoyed That Comfortable Fear positive exp #111556

    Bought a bottle of 12 pills on eBay after being introduced to the world of class Cs and having fun with codeine, benadryl etc. I had read quite a few trip reports before deciding to try it at a party that weekend.

    wagwangel · oral / 250 mg oral / 150 mg oral / repeated smoked
    Two Weeks in Valley Rehab positive exp #7684

    It was going to be a fun night. A Roll or two and be on our way to Club Groove. Well the rolls didn't work out. We were stuck. SO I decided to take my friends to the local wal-mart hook us up with a bottle of 100 Dramamine tablets. Well we had no idea how many to take so we I ate 21 Brad ate 21 Chris ate 23.

    Keith · Dramamine · 24 tablets oral
    Temporary Mental Retardation neutral exp #61018

    The following is a recent experience I had with Dramamine. Due to my inability to recall all that happened in this long endeavor, I've been filled in on some major events by a sober trip sitter, 'H.' Setting: About 8p.m. Good mindset. Took 600mg of Dramamine the previous night, but did not reach desired effects.

    Kota · Dimenhydrinate (Dramamine) · 900 mg oral
    Uncomfortable. Annoying. Not Worth Repeating. neutral exp #84346

    Cough syrup. Motion sickness pills. Allergy medication. All of these drugs I used to consider far beneath me. Kid's stuff. I'm an adult who has done a very, very wide variety of psychoactives, some way more than others, and all at very large doses.

    Psychedelic Magnate · Dimenhydrinate (Dramamine) · 600 mg oral
    Like Nothing Else neutral exp #58195

    I had been contemplating taking dimenhydrinate for the past while, just because I have easy access to it and it’s cheap. My mom wasn’t coming home after work and she wouldn’t be home until pretty late, so I decided that last night was perfect, and I sort of wrote a log for the beginning, starting at 5:00 P.M.

    Corvidae · 300 mg oral / 100 mg oral / 500 mg oral
    Spitting Venom Evil Satan cautionary exp #77124

    Beware of the true menace of the drug world that defies the toxic depiction of the deadly venom filled syringe that sits behind the reporters head, that vague yet lingering image that we become familiar with as yet another official sounding monotone drives the 'anti drug' message into this mindless society incessantly....

    psychoticbitch · 1 g oral
    Schizophrenic for Six Hours cautionary exp #29960

    Dose: 450 mg, a couple days after a 900-mg dose Setting: College dormitory, city campus, rainy night. Mindset: Awful. Broke up with my girlfriend the night before, was still half in denial. Aside from spending time with her, I had been generally bored with life and depressed for some time.

    jared · 450 mg oral
    Bluelight 8 threads 7 neutral 1 cautionary visit
    Dimenhydramine Dramamine Experienced Meeting The Shadows Once Again neutral

    17 Dramamine -- Experienced -- Meeting the shadows once again If you've ever tried Dramamine(I'm not sure how many have I just know it's heavily used where I come from)then this story should sound pretty familiar...Dramamine is the one drug that I've experienced,and I've experienced many,that consistently have the exac...

    scraped 2026-03-14
    Dramamine 500mg First W Dramamine Disney Land Adventure neutral

    Dosage: 500mg Dramamine Original Formula Form: Pills Administered: Orally Date: 3-28-2013 Health Issues: Sports Induced Asthma Preparation: Mental State of Mind: Relaxed/Happy Intent: To both study firsthand the effects, as well as compare the effects to Dramamine by Modest Mouse (Sorry if my grammar sucks.

    scraped 2026-03-14
    Dimenhydramine Dramamine First Time Title Here neutral

    Dramamine - First Time - Title Here First off, the reason I'm posting this is that people keep telling me they've heard they can take dramamine and it's just like acid! So, insted of telling them why this is wrong over and over I'm just gonna post this here so I can direct them to this thread.

    scraped 2026-03-14
    Dimenhydrinate Dramamine First Time Delerious neutral

    Dimenhydrinate I'm sure many of you are aware that if you take enough dramamine you will trip HARD. I was eager to find out exactly what the experience was like for myself and luckily the local gas station had many many boxes of this interesting chemical. I purchased 24 pills and consumed them when I got back home.

    scraped 2026-03-14
    Dimenhydramine Dramamine 2nd Time Strangeday neutral

    Dramamine --2ndTime-- StrangeDay About a month ago I was with my friend Kent at his Aunt Jen's house. I was bored out of my fucking mind. We were all sitting around in the living room watching TV and Kent was smoking a bong. Aunt Jen was getting drunk.

    scraped 2026-03-14
    Dimenhydrinate Dramamine First Time Good Day At School neutral

    here's my experience with dramamine Last year i was going to a charter school, kind of a party school where we didnt do any work or anything, and this girl i knew told me that dramamine could relly fuck me up. so i went across the street to publix and bought 2 bottles(12 in each bottle(i weighed about 115lbs.)).

    scraped 2026-03-14
    Dimenhydrinate 550mg First Time Memory Loss To Depression neutral

    8th may 2013 I'm a 140lbs male. I was sitting there in my room reading random experiences on erowid, when i came across a dimenhydrinate (dramamine) report. So I researched it a little further and decided to try it. Went to the pharmacy and got some.

    scraped 2026-03-14

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