DOEF
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 20 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 20 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Dimethoxyfluoroethylamphetamine
Summary
Extremely limited human data exists for DOEF beyond Shulgin's PiHKAL entry. Identity verification is essential as DOEF has been mis-sold as DOI or other DOx compounds. Use precise milligram scales and reagent testing for harm reduction.
Perspectives
“Somewhere between the first and second hour, I grew into a world that was slightly unworldly. Why? That is hard to say, as there was no appreciable visual component. I just knew that the place I was in was not completely familiar, and it was not necessarily friendly. But it was fascinating, and the music around me was magical. Time was moving slowly. I had to drive across the bay at about ten hours into this, and I was comfortable. That evening I slept well, but my dreams were pointless.”
Dose Information
Dose basis. Dose range compiled from Shulgin’s PIHKAL summary and community reports; potency is at the low-milligram level, so a 0.001 g (1 mg) scale or volumetric dosing is strongly advised. Start at the low end (≤1 mg) with an allergy test and avoid stacking doses due to delayed onset and long duration. Information is primarily from PIHKAL-derived summaries and anecdotal reports, not controlled studies. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-2mg | 2-3.5mg | 3.5-5mg | 5mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 1-3 hrs | 3-6 hrs | 4-6 hrs | 8.5-16.5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong body load with mild headspace and auditory effects, low visuals
Strong anxiety/jitters and euphoria with mild stimulation, low focus
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track DOEF there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
DOEF Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 1 · light 1-2 · common 2-3.5 · strong 3.5-5 · heavy 5+ Oral duration: onset 0.5-1.5h · come-up 1-3h · peak 3-6h · offset 4-6h · total 8.5-16.5h · after-effects 2-4h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 2.75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance patterns are inferred from classical serotonergic psychedelics (rapidly acquired after one dose; substantial decay within 5–7 days; near-baseline by ~2 weeks). No DOEF-specific human pharmacology; interindividual variability can be large.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Vasoconstriction
- Pupil dilation
- Increased perspiration
- Nausea
- Teeth grinding
- Insomnia
- Decreased appetite
- Cognitive Euphoria
- Analysis Enhancement
- Thought Connectivity
- Mindfulness
- Emotion Enhancement
- Wakefulness
- Euphoria
- Anxiety
- Time Distortion
- Music Enhancement
- Bodily Control Enhancement
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Light sensitivity
- Appetite suppression
- Dehydration
- Tactile intensification
- Drifting
Combinations
Cross-Check DOEF with another substancePiHKAL / TiHKAL
“Somewhere between the first and second hour, I grew into a world that was slightly unworldly. Why? That is hard to say, as there was no appreciable visual component. I just knew that the place I was in was not completely familiar, and it was not necessarily friendly. But it was fascinating, and the music around me was magical. Time was moving slowly. I had to drive across the bay at about ten hours into this, and I was comfortable. That evening I slept well, but my dreams were pointless.”
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for DOEF? Let us know. Reports are reviewed by moderators — this is not posted publicly.