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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Isopropylphenidate

    Aliases: ipd, iph, ipp, ippd, ipph

    Stimulant

    Summary PsychonautWiki

    Isopropylphenidate (also known as IPH, IPPH, IPD and IPPD) is a novel lesser-known stimulant of the phenidate chemical class. It is a structural analog of the widely-prescribed ADHD medication methylphenidate. It is a norepinephrine-dopamine reuptake inhibitor (NDRI).

    Dose Information PsychonautWiki TripSit

    ROA Light Common Strong Heavy
    Insufflated 5-10mg 10-20mg 20-35mg 35mg+
    Oral 5-15mg 15-25mg 25-45mg 45mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects PsychonautWiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Insufflated 0-6 min 12-30 min 1-2 hrs 60-90 min 1-8 hours 2.2-4.1 hrs
    Oral 12-30 min 18-42 min 1.5-2.5 hrs 1-2 hrs 1-8 hours 3-5.7 hrs

    Effect Profile

    7 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 3.8
    Moderate 4/10

    Strong anxiety/jitters with moderate stimulation and euphoria

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    6
    cognitive euphoria euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Isopropylphenidate
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 2d Half tolerance 3d Baseline ~7d

    Empirically modeled from community stimulant-use patterns; tolerance rises over consecutive days and substantially wanes over 1–2 weeks of abstinence. Data quality is anecdotal; individuals vary widely.

    Cross-Tolerances

    Methylphenidate
    60%
    Other phenidate stimulants (e.g., ethylphenidate, 4F-MPH)
    50%

    Effects Erowid

    Aggregated from 7 Erowid experience reports

    Positive Effects 3

    Focus Enhancement 71.4% 70%
    Stimulation 71.4% 70%
    Euphoria 57.1% 70%

    Adverse Effects 2

    Anxiety 71.4% 70%
    Jaw Clenching 57.1% 70%
    Isopropylphenidate's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 PsychonautWiki 📖 TripSit