WARNING: The following trip report may be found offensive to some, with all my heart, I solemnly apologize for that. Methoxetamine -- GOD IS LOVE (may be offensive to some) Whoever does not love does not know God, because God is love.
Methoxetamine
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 7 corroborating sources
- 4 ROAs with full dose ladders
- duration data present
- 26 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 7 corroborating sources
- 4 ROAs with full dose ladders
- duration data present
- 26 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Aliases: Mxe, Mexxy, M-ket, Roflcopter, 3-meo-2'oxo-pce
Summary
3-MeO-2'-Oxo-PCE (commonly known as Methoxetamine, MXE, Mexxy, among others) is a dissociative substance of the arylcyclohexylamine class that produces ketamine-like dissociative effects when administered. It is structurally related to ketamine, PCE, and 3-MeO-PCP. MXE was originally developed through the use of intelligent drug design, as a potential treatment for Phantom Limb Syndrome among other ailments.
Perspectives
“MXE is one of my favorite substances. The hole experience on it is substantially more colorful than with other dissociatives, it feels like an adventure is unfolding before me. It is stimulating and slightly manic, and highly euphoric. RIP MXE, you will be missed.”
“I was sorry not to have sampled it earlier.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual BA ~50% | 15-25mg | 25-35mg | 35-65mg | 65-80mg+ |
| Insufflated BA ~60% | 10-20mg | 20-35mg | 35-60mg | 60mg+ |
| Oral BA ~50% | 10-25mg | 25-45mg | 45-70mg | 70mg+ |
| Sublingual | 10-20mg | 40-60mg | 60-75mg | 75mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral / Sublingual | 15-45 min | 45-90 min | 1-3 hrs | 2-3 hrs | 3-5 hrs |
| Insufflated | 4-19 min | 30-75 min | 1-3 hrs | 1-3 hrs | 3-6 hrs |
| Intramuscular | 4-10 min | 15-30 min | 1-3 hrs | 2-3 hrs | 3-6 hrs |
| Rectal | 15-30 min | 30-60 min | 1-3 hrs | 2-3 hrs | 3-6 hrs |
| Oral | 12-30 min | 48-90 min | 1.5-2.5 hrs | 60-90 min | 3-6 hrs |
| Sublingual | 15-45 min | - | 3-6 hrs | - | 3-6 hrs |
Effect Profile
219 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 219 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
6.6
Strong+
7/10
Strong dissociative depth and insight with moderate mania and motor impairment
Dissociative Depth
×3
8
consciousness disconnection
depersonalization
derealization
tactile disconnection
physical disconnection
visual disconnection
+6 more
“It made all my problems wash away, you could say that I dissociated from themโฆ I was heartbroken as hell, but that suddenly became a passing feeling, an irrelevancy to the wide world of MXE.”
“Specifically I've noticed that when I had a lucid dream recently the quality of the experience felt nearly the same as a 'lucid hole' that I had a couple days previously.”
Mania / Compulsion
×1
7
mania
compulsive redosing
disinhibition
stimulation
“To me, I've already Died in the Hospital from a Heroin OD and they brought me back to Life - I've tried to take my Life during Manic Depressive Episodes................MXE has saved me from this...”
“I feel the rushing euphoria of the coming trip.”
Insight / Novel Thought
×2
8
conceptual thinking
analysis enhancement
introspection
perspective alterations
unity and interconnectedness
creativity enhancement
+2 more
“That's where it gets really interesting, and I am incorporating different pre-existing models of consciousness such as The Quantum Mind, Spin-Mediated Consciousness, Orch OR theory, quantum...”
“Is there such a thing as returning to being the same person after a meaningful experience?”
Motor / Sensory Impairment
×1
7
motor control loss
tactile disconnection
physical disconnection
tactile suppression
numbness
spatial disorientation
+2 more
“I feel cold and numb, with some nausea and burgeoning ataxia.”
User Experience
dissociative depth
“It made all my problems wash away, you could say that I dissociated from themโฆ I was heartbroken as hell, but that suddenly became a passing feeling, an irrelevancy to the wide world of MXE.”
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2โ4 weeks for noticeable reduction
Tolerance Decay
Half tolerance
7d
Baseline
~10d
A single heavy session can produce pronounced short-term tolerance. Many users report tolerance halves over ~3โ5 days and returns near-baseline after ~10โ14 days; data are anecdotal and vary widely by dose pattern and ROA. Cross-tolerance within the arylcyclohexylamine class is expected. Data quality: anecdotal/community reports.
Cross-Tolerances
Effects
Aggregated from 219 Erowid experience reports
Positive Effects 11
Music Enhancement
52.1%
70%
Euphoria
43.8%
70%
Color Enhancement
38.4%
70%
Empathy
35.6%
70%
Stimulation
33.8%
70%
Tactile Enhancement
28.3%
70%
Focus Enhancement
26.5%
70%
Introspection
21.0%
70%
Body High
15.5%
70%
Pain Relief
7.3%
70%
Creativity Enhancement
5.9%
70%
Adverse Effects 12
Anxiety
45.7%
70%
Confusion
41.6%
70%
Motor Impairment
20.5%
70%
Nausea
18.7%
70%
Memory Suppression
15.5%
70%
Increased Heart Rate
8.2%
70%
Headache
7.3%
70%
Psychosis
7.3%
70%
Pupil Dilation
4.1%
70%
Thought Loops
4.1%
70%
Muscle Tension
3.7%
70%
Sweating
3.2%
70%
Combinations
Cross-Check Methoxetamine with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
As I sit here wondering exactly what it was I was up to in the first place, I find myself yet again with my family. I have just insufflated about .2 of MXE given to me by a wonderful chemist in China. Many good vibrations sent his way for putting his love and care into this product, or so I hope.
I did MXE for the first time yesterday, and I want to share my experience. Some background: Iยve had many trips on many different substances, of which ketamine has always been a favorite. Back when MXE was still around, I got curious about it and ordered some.
This was my first experience with methoxetamine, after many years of searching for it. I had all but given up hope of finding it by this point, when unexpectedly I was fortunate enough to make a new friend, who would then be kind enough to offer me 250 mg of high quality methoxetamine that they have had sitting for yea...
Now not a meticulous account of how much was taken at what time but an account of the events surrounding me running through a bit more than a gram in five days. I'll try keep it from becoming this huge wall of text, buy I just know it will. Sorry for that.
Day 1: The first dose was consumed around the 22:00 mark. I was in my living room, accompanying T. I had consumed the first 20 mg via gel capsule (T. preferred to bump his). We began the trip with me pulling out Abalone and teaching T.
Too Much MXE for Me It started when we got back to the house, around 11am. We left the house about 1pm the day before so it had been a looooong party. As soon as we started to chill out the house I thought I did not feel right. I felt I noticed things a lot more and I was starting to feel weird.
Warning: I'm not a native English speaker As an avid DXM user in the past, I've decided to try methoxetamine. I've never tried PCP or ketamine, though I think if presented with such option, I will at least once, as DXM's dissociative effects seem to really agree with me (I've used benzydamine, a little-known deliriant...
Bluelight 8 threads 3 positive 5 neutral visit
WARNING: The following trip report may be found offensive to some, with all my heart, I solemnly apologize for that. Methoxetamine -- GOD IS LOVE (may be offensive to some) Whoever does not love does not know God, because God is love. 1 John 4:8 Click to expand... Hi gang! Its been a while since my last trip report.
Methoxetamine-Life changing Methox Hole (M-hole) Age: 22 (3 years ago) Experience with drugs at that time: weed, hash, xtc/mdma, speed, ketamine, cocaine, 4fmp and methoxetamine Other substances taken before this trip: alcohol-I guess 15 beers or something like that DOse Methoxetamine: not sure, but I think at least 15...
MXE (SOBER except for Buprenorphine) MXE used to be a great drug for me. I enjoyed it quite a bit. I would snort it and enjoyed it quite a bit. I went on a road trip with it. I drove 112 MPH on it with loud music.
I had just recently my first true +4 experience from 100 mg MXE plugged combined with small amounts of weed (a bowl or two of very weak leftover leaves, thank god no strong bud!).
This was the night I learned more in one night than I have ever learned in my entire life. I took way too much MXE while learning what the chemical can do and went in and out of consciousness, several times, repeatedly, because it felt very very good and I was in communication with energies from other dimensions.
This was my first experience with methoxetamine, after many years of searching for it. I had all but given up hope of finding it by this point, when unexpectedly I was fortunate enough to make a new friend, who would then be kind enough to offer me 250 mg of high quality methoxetamine that they have had sitting for yea...
Sex: Male Age: 46 Weight: 182 lbs (13 Stone) Experience: First Time on MXE General Experience (in order of first time): Cannabis Psilocybin Mushrooms (Psilocybe Semilanceata) Amphetamine Sulphate Opium LSD Heroin Benzodiazepines Cocaine Methadone MDMA Crack Cocaine MXE Medication: Currently prescribed 60mg daily of Met...
Compound: Methoxetamine (2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone) Total amount taken: 100mg Description of drug: White powder, quite fine. A pleasure to snort. My previous drug experience: have taken MDMA and ecstacy waaay too much over the past 8 years or so.
Bluelight Reference Guide
โ Official โ The Big & Dandy Methoxetamine / MXE Thread - Part 17 - South-Kansas is going bye-bye
The Big & Dandy Methoxetamine / MXE Thread - Part 17 - South-Kansas is going bye-bye Welcome to the Big & Dandy Methoxetamine Thread (V. 17) Previous B&D's sorted from most recent to least recent: Version 16 "Sweet 16 Mind Control Machine" The most previous MXE Thread v15 The somewhat previous MXE thread v14 The semi r...
Read full thread on Bluelight โ
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