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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methyl-K Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Mbdp, Uwa-091

    Summary dose.wiki

    Data are extremely scarce: only one formal PiHKAL trial (100 mg oral produced no overt effects) and a handful of 2025 forum / Reddit self-experiments. Community consensus places active oral dosing somewhere in the low-hundreds of milligrams, broadly mirroring its ethyl homologue MBDB but requiring approximately 25-40% higher weight due to weaker serotonin release. Bluelight users describe mild 'wired but clear' stimulation, elevated heart-rate (90-110 bpm resting) and difficulty sleeping for over 8 hours after 200 mg or more.

    Perspectives

    “There were no effects. I was busy and totally wound up and didnโ€™t sleep until 3 a.m., but this was probably unrelated to the Me-K.”

    Dose Information dose.wiki

    ROA Threshold
    Oral 75mg
    Insufflated 40mg
    Rectal 40mg
    Vaporized / Smoked 5mg

    Only a threshold dose is documented for this substance โ€” the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.

    Onset, Duration & After-effects dose.wiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-60 min 1-3 hrs 2-3 hrs 2-12 hrs 3.5-7 hrs
    Insufflated 5-15 min 1-3 hrs 2-3 hrs 2-12 hrs 3.08-6.25 hrs
    Rectal - 1-3 hrs 2-3 hrs 2-12 hrs 3-6 hrs
    Vaporized / Smoked 1-3 min 1-3 hrs 2-3 hrs 2-12 hrs 3.02-6.05 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 4.6
    Moderate+ 5/10

    Moderate stimulation and sensory enhancement with mild empathy, low euphoria

    Empathy / Social Openness ×3
    4
    increased sociability subtle empathogenic warmth
    Euphoria / Mood Elevation ×2
    3
    euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 3.5
    Moderate 4/10

    Strong anxiety/jitters with moderate stimulation, low euphoria and focus

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    3
    euphoria
    Focus / Productivity ×2
    2
    thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety tachycardia teeth grinding increased heart rate jaw clenching vasoconstriction
    Based on reports from:

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Methyl-K there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Methyl-K
    Unit
    mg
    Description
    Methyl-K
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 75
    Insufflated dose (mg): threshold 40
    Rectal dose (mg): threshold 40
    Vaporized / Smoked dose (mg): threshold 5
    
    Oral duration: onset 0.5-1h ยท peak 1-3h ยท offset 2-3h ยท total 3.5-7h ยท after-effects 2-12h
    Insufflated duration: onset 5-15m ยท peak 1-3h ยท offset 2-3h ยท total 3.08-6.25h ยท after-effects 2-12h
    Rectal duration: peak 1-3h ยท offset 2-3h ยท total 3-6h ยท after-effects 2-12h
    Vaporized / Smoked duration: onset 1-3m ยท peak 1-3h ยท offset 2-3h ยท total 3.02-6.05h ยท after-effects 2-12h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2โ€“4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives
    Ketamine
    30%
    PCP
    30%

    Effects dose.wiki

    Positive
    • Clean Mental Stimulation
    • Stimulation
    Negative
    • Jaw Clenching
    • Tachycardia
    • Insomnia
    • Post-use Fatigue
    • Teeth grinding
    • Increased heart rate
    • Pupil dilation
    • Vasoconstriction
    Positive
    • Subtle Empathogenic Warmth
    • Mild Euphoria
    • Increased Sociability
    • Alertness enhancement
    • Euphoria
    • Wakefulness
    Negative
    • Anxiety
    Neutral
    • Talkativeness
    • Thought acceleration
    • Time distortion
    Positive
    • Increased music appreciation
    • Tactile enhancement
    • Increased libido
    • Tracers
    • Color enhancement
    • Pattern recognition enhancement
    Negative
    • Light sensitivity
    • Dehydration
    • Appetite suppression
    • Disinhibition

    Combinations

    Cross-Check Methyl-K with another substance

    PiHKAL / TiHKAL Shulgin

    PiHKAL #129: METHYL-K

    “There were no effects. I was busy and totally wound up and didnโ€™t sleep until 3 a.m., but this was probably unrelated to the Me-K.”

    โ€” Alexander Shulgin, PiHKAL (with 100 mg)

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