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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methyl-K

    Aliases: Mbdp, Uwa-091

    Stimulant Research-chemical

    Summary TheDrug.Wiki

    Data are extremely scarce: only one formal PiHKAL trial (100 mg oral produced no overt effects) and a handful of 2025 forum / Reddit self-experiments. Community consensus places active oral dosing somewhere in the low-hundreds of milligrams, broadly mirroring its ethyl homologue MBDB but requiring approximately 25-40% higher weight due to weaker serotonin release. Bluelight users describe mild 'wired but clear' stimulation, elevated heart-rate (90-110 bpm resting) and difficulty sleeping for over 8 hours after 200 mg or more.

    Perspectives

    “There were no effects. I was busy and totally wound up and didn’t sleep until 3 a.m., but this was probably unrelated to the Me-K.”

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset After Effects
    Oral 30-60 min 1-3 hrs 2-3 hrs 2-12 hrs
    Insufflated 5-15 min 1-3 hrs 2-3 hrs 2-12 hrs
    Vaporized / Smoked 1-3 min 1-3 hrs 2-3 hrs 2-12 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 4.6
    Moderate+ 5/10

    Moderate stimulation and sensory enhancement with mild empathy, low euphoria

    Empathy / Social Openness ×3
    4
    increased sociability subtle empathogenic warmth
    Euphoria / Mood Elevation ×2
    3
    euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 3.5
    Moderate 4/10

    Strong anxiety/jitters with moderate stimulation, low euphoria and focus

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    3
    euphoria
    Focus / Productivity ×2
    2
    thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety tachycardia teeth grinding increased heart rate jaw clenching vasoconstriction
    Based on reports from:
    PiHKAL PiHKAL #129: METHYL-K Erowid Experience Reports PsychonautWiki Methyl-K
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives
    Ketamine
    30%
    PCP
    30%
    Methoxetamine
    30%

    Effects TheDrug.Wiki

    Positive
    • Clean Mental Stimulation
    • Stimulation
    Negative
    • Jaw Clenching
    • Tachycardia
    • Insomnia
    • Post-use Fatigue
    • Teeth grinding
    • Increased heart rate
    • Pupil dilation
    • Vasoconstriction
    Positive
    • Subtle Empathogenic Warmth
    • Mild Euphoria
    • Increased Sociability
    • Alertness enhancement
    • Euphoria
    • Wakefulness
    Negative
    • Anxiety
    Neutral
    • Talkativeness
    • Thought acceleration
    • Time distortion
    Positive
    • Increased music appreciation
    • Tactile enhancement
    • Increased libido
    • Tracers
    • Color enhancement
    • Pattern recognition enhancement
    Negative
    • Light sensitivity
    • Dehydration
    • Appetite suppression
    • Disinhibition

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #129: METHYL-K

    “There were no effects. I was busy and totally wound up and didn’t sleep until 3 a.m., but this was probably unrelated to the Me-K.”

    — Alexander Shulgin, PiHKAL (with 100 mg)
    Methyl-K's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki