Summary
MiPLA is a research chemical with very limited history of human use and minimal scientific study of its pharmacology, metabolism, and toxicity. It is approximately two to three times less potent than LSD and has a notably shorter duration of around 4-6 hours. The substance is generally described as producing less anxiety and a lighter headspace compared to LSD, with more recreational and social characteristics. Individuals with personal or family history of mental illness should avoid use. Use precise weighing equipment and employ harm reduction practices including careful set and setting preparation.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-150µg | 150-200µg | 200-250µg | 300µg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 19-40 min | 45-90 min | 1.0-2.0 hrs | 1.0-2.0 hrs |
Tolerance
Build-up
develops rapidly after a single use (lysergamide)
Reset
7–14 days for baseline
Cross-tolerance
Effects
Positive
- Stimulation
- Physical Euphoria
- Physical euphoria
Negative
- Nausea
- Increased heart rate
- Pupil dilation
- Insomnia
- Spontaneous Bodily Sensations
- Increased Bodily Temperature
- Sedation
Positive
- Cognitive Euphoria
- Analysis Enhancement
- Emotion Enhancement
- Conceptual Thinking
- Euphoria
Negative
- Anxiety
- Time Distortion
- Thought Acceleration
- Ego Death
- Time distortion
Positive
- Tactile Enhancement
- Visual Acuity Enhancement
- Color Enhancement
- Pattern Recognition Enhancement
- Increased Music Appreciation
- Increased music appreciation
Negative
- Appetite suppression
- Dehydration
- Light sensitivity
- Visual Drifting