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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MXiPr

    Aliases: Mxip, Isopropyxetamine, 3-meo-2-oxo-pcipr, Isopropyloxetamine, 3-methoxy-2-oxo-pcipr

    Dissociative Research-chemical

    Summary TheDrug.Wiki PsychonautWiki

    3-MeO-2′-Oxo-PCiPr (also known as MXiPr) is a novel dissociative substance of the arylcyclohexylamine class. It is a structural analog of MXE. The mechanism of action is not known, but it is likely an NMDA receptor antagonist, producing dissociative and euphoric effects.

    Perspectives

    “MXiPr is an ambrosia, a glistening food for the gods. It is an exciting adventurous hallucinatory journey through virtual reality, a roller coaster ride or a joyride in a little plane above a technicolor canyon, all replete with a genuine sense of motion and travel.”

    Dose Information TheDrug.Wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-20mg 20-40mg 40-60mg 60mg+
    Insufflated 10-20mg 20-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 15-45 min 30-60 min 0.75-2 hrs 1-2 hrs 1-3 hrs
    Insufflated 4-15 min 15-30 min 45-90 min 1-2 hrs 1-3 hrs

    Effect Profile

    8 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 5.1
    Moderate+ 5/10

    Strong dissociative depth, mania, and motor impairment with low insight

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection visual disconnection perception of bodily lightness spatial disorientation +1 more
    ⚠ Mania / Compulsion ×1
    10
    mania disinhibition stimulation euphoria
    Insight / Novel Thought ×2
    3
    conceptual thinking
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection
    Based on reports from:
    Effect Index Tainted Euphoria Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki MXiPr
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 3d Half tolerance 7d Baseline ~14d

    Rapid acute tolerance is commonly reported within sessions; inter-session tolerance declines over 1–3 weeks. Data are anecdotal and extrapolated from ketamine/MXE patterns.

    Cross-Tolerances

    ketamine
    60%
    MXE
    60%
    other arylcyclohexylamines
    50%

    Effects Erowid

    Aggregated from 8 Erowid experience reports

    Positive Effects 8

    Euphoria 87.5% 70%
    Music Enhancement 62.5% 70%
    Color Enhancement 50.0% 70%
    Empathy 50.0% 70%
    Focus Enhancement 50.0% 70%
    Body High 50.0% 70%
    Stimulation 50.0% 70%
    Tactile Enhancement 37.5% 70%

    Adverse Effects 1

    Confusion 37.5% 70%

    Combinations TripSit

    Trip Reports Effect Index

    Tainted Euphoria utheraptor
    MXiPr's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 Bluelight 📖 PsychonautWiki