T0:00- Take my dose intranasally- itΒs a large pile of light, chalky powder that I am not able to take down in one go. The odor is reminiscent of sour plastic and burning rubber and it stings briefly upon contact, though this quickly retreats instead of smoldering and lingering.
MXiPr
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Aliases: Mxip, Isopropyxetamine, 3-meo-2-oxo-pcipr, Isopropyloxetamine, 3-methoxy-2-oxo-pcipr
Summary
3-MeO-2β²-Oxo-PCiPr (also known as MXiPr) is a novel dissociative substance of the arylcyclohexylamine class. It is a structural analog of MXE. The mechanism of action is not known, but it is likely an NMDA receptor antagonist, producing dissociative and euphoric effects.
Perspectives
“MXiPr is an ambrosia, a glistening food for the gods. It is an exciting adventurous hallucinatory journey through virtual reality, a roller coaster ride or a joyride in a little plane above a technicolor canyon, all replete with a genuine sense of motion and travel.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-40mg | 40-60mg | 60mg+ |
| Insufflated | 10-20mg | 20-40mg | 40-60mg | 60mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 0.75-2 hrs | 1-2 hrs |
| Insufflated | 4-15 min | 15-30 min | 45-90 min | 1-2 hrs |
Effect Profile
8 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
5.1
Moderate+
5/10
Strong dissociative depth, mania, and motor impairment with low insight
Dissociative Depth
×3
10
depersonalization
derealization
physical disconnection
visual disconnection
perception of bodily lightness
spatial disorientation
+1 more
Mania / Compulsion
×1
10
mania
disinhibition
stimulation
euphoria
Insight / Novel Thought
×2
3
conceptual thinking
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
numbness
spatial disorientation
visual disconnection
Based on reports from:
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2β4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
3d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session β the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Rapid acute tolerance is commonly reported within sessions; inter-session tolerance declines over 1β3 weeks. Data are anecdotal and extrapolated from ketamine/MXE patterns.
Cross-Tolerances
Effects
Aggregated from 8 Erowid experience reports
Positive Effects 8
Euphoria
87.5%
70%
Music Enhancement
62.5%
70%
Color Enhancement
50.0%
70%
Empathy
50.0%
70%
Focus Enhancement
50.0%
70%
Body High
50.0%
70%
Stimulation
50.0%
70%
Tactile Enhancement
37.5%
70%
Adverse Effects 1
Confusion
37.5%
70%
Combinations
Cross-Check MXiPr with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 6 reports 6 neutral visit
MXiPR: Trip Report, Effects Summary, and Combination -Introduction- I was recently blessed with a small quantity of MXiPR (3-MeO-2β²-Oxo-PCiPr). I'd been hoping to get my hands on some for months, and I was overjoyed to finally experience it for myself.
First-Time MXiPr Experience (48mg Insufflated) I wanted to share a "trip" report for this substance, as I haven't seen much on it, and the more information available for all, the more harm reduction (and fun) we can all experience.
[This report may be describing an experience also described in the first part of Report #115940 by the same author.] Start off by saying I'm a fat k head. I've tried many a dissos heres a list for reference so u can take my vouch for mxipr as serious.
Β Setting: At home, in my bed Β Tolerance: Maybe a little, but not much (I use dissos 1-2 p. month on average). Last experience was a k-hole 17 days ago. Β Prior disso experience: R,S-ketamine: 25x (at least) // 2-FDCK: 5x // DCK: 5x // Nitrous Oxide: 5x // DXM (low dose): 3x // 3-MeO-PCE: 2x // 3-MeO-PCP: 1x // MXPr:...
I had just received 500mg of MxiPr from a well-known research chemicals website and I was very eager to try it, alone with my cat, for scienceΒs sake. I weighed 50mg of the white chalky powder, which is quite a strong dose .
Bluelight 1 thread 1 neutral visit
Age: 25 Weight: 130 lbs Dosage: 60 mg intranasal Setting: My house T0:00- Take my dose intranasally- itβs a large pile of light, chalky powder that I am not able to take down in one go.
Bluelight Reference Guide
Dissociatives The Big & Dandy 3-MeO-2β²-oxo-PCiPr (MXiPr) Thread
This one has potentially surfaced and it looks extremely intriguing. Very similar structurally to both MXE & MXPr. I ordered some and it has shipped so I'm excited to test it out and compare to the aforementioned. Will send off for analytical confirmation as well.
Read full thread on Bluelight β
MXiPr's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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