TMA-2
Aliases: Domeo, 2,5-dimethoxy-4-methoxyamphetamine
Categories
Summary
TMA-2 is a synthetic psychedelic amphetamine that is notably more potent than its positional isomer TMA (3,4,5-trimethoxyamphetamine). It has a limited history of human use and is known for producing unique stimulating effects with less pronounced visual distortions compared to mescaline. Anecdotal reports indicate TMA-2 is dose-sensitive and can produce uncomfortable body load, nausea, and overstimulation. The substance is rarely available on the street market and is primarily obtained as a research chemical. Legal status varies by jurisdiction; it is Schedule I in the United States and controlled in many European countries.
Perspectives
“TMA-2 is a challenging but rewarding experience, worthwhile for those willing to suffer the massive lingering bodyload and the overwrought, nonstop stimulation.”
“I took it in two 10 milligram doses, spaced by two hours. There was a slight movement of surface textures, my hearing was deepened and spatially defined. The body was relaxed and stretching seemed necessary. The further I got into it the more I realized that I was totally lazy. Very lethargic, to the point of laughter. At the sixth hour, I was seeing more life in the woodwork, and the wooden angel hanging on the ceiling was flesh and feathers when I stared at it. Great vision. But by no means overwhelming. Sleep was fine.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-40mg | 40-60mg | 60mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 0.33-2 hrs | 1.5-3 hrs | 4-6 hrs | 2-4 hrs | 4-24 hrs | 360-0 min |
| Insufflated | 10-30 min | 30-60 min | 4-6 hrs | 2-4 hrs | 6-12 hrs | 360-0 min |
| Rectal | 10-30 min | 30-60 min | 4-7 hrs | 3-5 hrs | 6-12 hrs | 360-0 min |
| Vaporized | 5-15 min | 20-40 min | 3-6 hrs | 2-4 hrs | 4-12 hrs | 360-0 min |
Tolerance
Effects
- Stimulation
- Spontaneous Tactile Sensations
- Mental/physical stimulation
- Pupil dilation
- Increased blood pressure
- Vasoconstriction
- Nausea
- Restlessness
- Sweating/chills
- Muscle tension
- Insomnia
- Spontaneous bodily sensations
- Decreased appetite
- Empathy enhancement
- Sociability enhancement
- Analysis enhancement
- Thought connectivity
- Conceptual thinking
- Emotion enhancement
- Wakefulness
- Empathy And Sociability Enhancement
- Euphoria
- Empathy
- Insight
- Confusion
- Time distortion
- Thought acceleration
- Change in perception
- Ego softening
- Tactile enhancement
- Bodily control enhancement
- Color enhancement
- Pattern recognition enhancement
- Visual acuity enhancement
- Color shifting
- Increased music appreciation
- Colour Enhancement
- Increased Libido
- Music Appreciation Enhancement
- Brightened colour
- Enhanced tactile sensation
- After images
- Drifting
- Symmetrical texture repetition
- Diffraction
- Auditory distortion
- Closed/Open eye visuals
Combinations
PiHKAL / TiHKAL
“I took it in two 10 milligram doses, spaced by two hours. There was a slight movement of surface textures, my hearing was deepened and spatially defined. The body was relaxed and stretching seemed necessary. The further I got into it the more I realized that I was totally lazy. Very lethargic, to the point of laughter. At the sixth hour, I was seeing more life in the woodwork, and the wooden angel hanging on the ceiling was flesh and feathers when I stared at it. Great vision. But by no means overwhelming. Sleep was fine.”