Summary
Very limited human data exist. 2-MAPB appears pharmacologically similar to MDMA based on rodent studies. Potency varies between vendors; always reagent-test samples. Marked vasoconstriction, bruxism, and elevated heart rate have been reported. Keep hydrated (approximately 250 ml water per hour) and avoid overheating.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | - | - | 140+mg(notrecommended)+ |
| Insufflated | - | - | - | 80+mg(stronglydiscouraged)+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 30-80 min | 30-60 min | 1-3 hrs | 2-3 hrs | 2-24 hrs |
| Insufflated | 5-20 min | 15-30 min | 1-2 hrs | 1-2 hrs | 2-24 hrs |
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Effects
Positive
- Stimulation
Negative
- Pupil dilation
- Bruxism
- Vasoconstriction
- Increased heart rate
- Increased blood pressure
- Insomnia
- Nausea
- Teeth grinding
- Difficulty urinating
Positive
- Empathy enhancement
- Euphoria
- Sociability enhancement
- Wakefulness
- Increased sociability
- Mood lift
Negative
- Anxiety
- Thought deceleration
- Time distortion
- Thought acceleration
Positive
- Tactile enhancement
- Music appreciation
- Visual acuity enhancement
- Increased music appreciation
- Bodily control enhancement
- Increased libido
- Tracers
Negative
- Light sensitivity
- Auditory hallucination
- Auditory distortion