Summary
2-NMC (BMAPN) is a synthetic cathinone with a naphthalene ring substitution that exhibits potent dopaminergic activity and abuse potential in animal models. Virtually no controlled human pharmacology data exists. Animal studies indicate it produces locomotor sensitization, decreases dopamine transporter expression, and increases dopamine D2 receptor gene expression in the striatum. Often mis-sold as 'NRG-3' (a brand name that typically contained MDPV or ฮฑ-PVP instead). Marked nasal mucosa irritation when insufflated; eye/airway irritation when vaporized.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 15-35 min | 30-60 min | 1-2.5 hrs | 1-2 hrs | 2-6 hrs |
| Insufflated | 2-5 min | 5-15 min | 1-2.5 hrs | 1-2 hrs | 2-6 hrs |
| Vaporized | 1-2 min | 2-5 min | 30-90 min | 30-60 min | 2-4 hrs |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
Negative
- Pupil dilation
- Increased heart rate
- Vasoconstriction
- Perspiration
- Jaw tension and bruxism
- Restlessness
- Fatigue
Positive
- Euphoria
- Increased motivation
- Empathy and sociability
- Enhanced music appreciation
Negative
- Anxiety
- Cognitive impairment
- Depression
- Talkativeness
Positive
Negative
- Light sensitivity
- Sexual arousal