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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2-NMC Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 3 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical

    Aliases: Bmapn, Ξ²k-methamnetamine

    Stimulant Research-chemical

    Summary dose.wiki TripSit

    2-NMC (BMAPN) is a synthetic cathinone with a naphthalene ring substitution that exhibits potent dopaminergic activity and abuse potential in animal models. Virtually no controlled human pharmacology data exists. Animal studies indicate it produces locomotor sensitization, decreases dopamine transporter expression, and increases dopamine D2 receptor gene expression in the striatum.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. Ranges are compiled from user reports; potency varies significantly by batch and mislabeling is commonβ€”always allergy test (1–2 mg), then titrate. Verify identity with at least one reagent and, where possible, a lab service (FTIR/GC–MS/LC–MS). Nasal use is frequently irritating with cathinones; use finely crushed material, small lines, and saline rinse. Increased cardiovascular load and compulsive redosing risk versus oral. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 25-50mg 50-120mg 120-180mg 180mg+
    Insufflated 15-25mg 25-60mg 60-90mg 90mg+
    Vaporized 5-10mg 10-20mg 20-30mg 30mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-35 min 30-60 min 1-2.5 hrs 1-2 hrs 2-6 hrs 2.75-6.08 hrs
    Insufflated 2-5 min 5-15 min 1-2.5 hrs 1-2 hrs 2-6 hrs 2.11-4.83 hrs
    Vaporized 1-2 min 2-5 min 30-90 min 30-60 min 2-4 hrs 1.04-2.61 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 3.3
    Light+ 3/10

    Mild stimulation with low empathy, euphoria, and sensory enhancement

    Empathy / Social Openness ×3
    3
    empathy and sociability
    Euphoria / Mood Elevation ×2
    3
    euphoria
    Stimulation ×1
    5
    stimulation restlessness increased heart rate
    Sensory Enhancement ×1
    3
    enhanced music appreciation
    Stimulant 2.4
    Light 2/10

    Strong anxiety/jitters with mild euphoria, low stimulation

    Stimulation / Energy ×3
    3
    stimulation
    Euphoria / Mood Lift ×2
    5
    euphoria increased motivation
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate vasoconstriction perspiration
    View methodology →

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 2-NMC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "2-NMC (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    2-NMC
    Unit
    mg
    Description 
    2-NMC
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 10 Β· light 25-50 Β· common 50-120 Β· strong 120-180 Β· heavy 180+
Insufflated dose (mg): threshold 5 Β· light 15-25 Β· common 25-60 Β· strong 60-90 Β· heavy 90+
Vaporized dose (mg): threshold 5 Β· light 5-10 Β· common 10-20 Β· strong 20-30 Β· heavy 30+

Oral duration: onset 15-35m Β· come-up 0.5-1h Β· peak 1-2.5h Β· offset 1-2h Β· total 2.75-6.08h Β· after-effects 2-6h
Insufflated duration: onset 2-5m Β· come-up 5-15m Β· peak 1-2.5h Β· offset 1-2h Β· total 2.11-4.83h Β· after-effects 2-6h
Vaporized duration: onset 1-2m Β· come-up 2-5m Β· peak 0.5-1.5h Β· offset 0.5-1h Β· total 1.04-2.61h Β· after-effects 2-4h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 85 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~7d

    Based on stimulant cross‑tolerance heuristics and user reports; frequent redosing within a day rapidly diminishes effects. Allow at least 1–2 weeks between sessions for baseline sensitivity to return.

    Cross-Tolerances

    Other cathinones (e.g., 3‑MMC, 4‑MMC)
    70%
    Amphetamines
    50%
    MDMA
    40%

    Effects dose.wiki

    Positive
    • Stimulation
    Negative
    • Pupil dilation
    • Increased heart rate
    • Vasoconstriction
    • Perspiration
    • Jaw tension and bruxism
    • Restlessness
    • Fatigue
    Positive
    • Euphoria
    • Increased motivation
    • Empathy and sociability
    • Enhanced music appreciation
    Negative
    • Anxiety
    • Cognitive impairment
    • Depression
    Neutral
    • Talkativeness
    Negative
    • Light sensitivity
    Neutral
    • Sexual arousal

    Combinations

    Cross-Check 2-NMC with another substance

    2-NMC's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    πŸ“˜ Experience Reports πŸ“– dose.wiki πŸ“– PsychonautWiki