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    Disclaimer
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25H-NBOMe

    Aliases: 25h, 2c-h-nbome, Nbome-2c-h, 25-h-nbome

    Categories

    Psychedelic Stimulant Research-chemical
    25H-NBOMe structure

    Summary TheDrug.Wiki TripSit

    25H-NBOMe is the N-(2-methoxybenzyl) derivative of 2C-H. Compared with halogenated NBOMes (25I/25C/25B), it shows drastically weaker 5-HT2A potency (approximately 675-fold lower than 25I-NBOMe in vitro) and a pronounced adrenergic/vasoconstrictive profile. Because of low psychedelic potency, users may attempt multi-milligram doses, greatly increasing peripheral toxicity risk (tachycardia, hypertension, vasospasm). Very limited human data exists; serious adverse reactions (panic, chest pain, prolonged hypertension) have been reported. Use extreme caution with accurate milligram scales, start with allergy test (<0.25 mg), and avoid redosing.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Sublingual - - - 10mg+(NOTRECOMMENDED)+
    Insufflated - - - 5mg+(NOTRECOMMENDED)+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Sublingual 15-45 min 30-60 min 1-3 hrs 2-4 hrs 2-6 hrs 180-0 min
    Insufflated 5-15 min 15-30 min 1-3 hrs 2-4 hrs 2-6 hrs 180-0 min

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Effects TheDrug.Wiki TripSit

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Pupil dilation
    • Increased heart rate
    • Increased blood pressure
    • Vasoconstriction
    • Temperature regulation suppression
    • Muscle tension
    • Nausea
    • Restlessness
    • Sweating/chills
    • Insomnia
    Neutral
    • Mouth numbing
    • Decreased appetite
    Positive
    • Analysis enhancement
    • Conceptual thinking
    • Emotion enhancement
    • Wakefulness
    • Euphoria
    • Empathy
    • Insight
    Negative
    • Thought deceleration
    • Anxiety
    • Paranoia
    • Confusion
    • Memory suppression
    Neutral
    • Thought acceleration
    • Time distortion
    • Change in perception
    • Ego softening
    Positive
    • Perception of bodily lightness
    • Visual acuity enhancement
    • Colour enhancement
    • Pattern recognition enhancement
    • Increased music appreciation
    • Brightened colour
    • Enhanced tactile sensation
    Negative
    Neutral
    • Drifting
    • Internal hallucination
    • Closed/Open eye visuals

    Combinations TripSit

    Helpful Links

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