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    Disclaimer
    ☠ This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2C-B-FLY-NBOMe Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 19 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: Cimbi-31, Nbome-2c-b-fly, 2cbflynbome

    Summary dose.wiki

    Microgram-scale potency requires precise measurement - always use a 0.001 g (1 mg) accurate scale or volumetric dosing. Many NBOMe hospitalizations and fatalities involved misidentified blotters; 2C-B-FLY-NBOMe has a distinctly bitter/metallic taste and oral inactivity when swallowed. Produces stronger peripheral vasoconstriction than parent 2C-B-FLY - cold extremities and limb numbness are common.

    Dose Information dose.wiki TripSit Drugs.Wiki

    Dose basis. Microgram-active; weigh with a 0.001 g (1 mg) scale at minimum and strongly prefer volumetric dosing to reduce dosing error. Some NBOMe materials exist as freebase, HCl salt, or HPBCD complexes with differing solubility/bioavailability; dose-equivalence can vary. Avoid swallowing until after 20–30 minutes if testing blotter; oral (swallowed) activity for NBOMes is generally low but not zero for some salts, so do not assume inactivity. Volumetric dosing guide: dissolve a precisely weighed amount into a known volume of suitable solvent (e.g., high-proof ethanol or propylene glycol, not plain water for poorly water-soluble freebases), label concentration, and measure volume for dosing. Hold between gum and lip for 20–40 min; similar cautions as sublingual. Bitter/metallic taste is commonly reported with NBOMes and is a warning sign if a blotter was sold as LSD. Do not rely on taste aloneβ€”confirm identity with reagents/UV as available. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Sublingual 150-300Β΅g 300-600Β΅g 600-900Β΅g 900Β΅g+
    Buccal 200-350Β΅g 350-650Β΅g 650-950Β΅g 950Β΅g+
    Insufflated 200-400Β΅g 400-700Β΅g 700-900Β΅g 900Β΅g+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki TripSit Drugs.Wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Sublingual 10-40 min 30-60 min 2-4 hrs 3-5 hrs 4-12 hrs 5.67-10.67 hrs
    Buccal 10-40 min 30-60 min 2-4 hrs 3-5 hrs 4-12 hrs 5.67-10.67 hrs
    Insufflated 5-15 min 20-40 min 2-4 hrs 3-5 hrs 4-12 hrs 5.41-9.92 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.0
    Intense 8/10

    Strong visuals, body load, and headspace with moderate auditory effects

    Visual Intensity ×3
    10
    colour enhancement tracers drifting synaesthesia visual enhancement pattern recognition enhancement +1 more
    Headspace Depth ×3
    9
    conceptual thinking thought connectivity introspection emotion enhancement time distortion
    Auditory Effects ×1
    7
    auditory enhancement synaesthesia
    Body Load / Somatic Effects ×1
    10
    vasoconstriction nausea temperature regulation suppression teeth grinding increased heart rate
    Empathogen 4.9
    Moderate+ 5/10

    Strong sensory enhancement with moderate stimulation, mild euphoria, low empathy

    Empathy / Social Openness ×3
    3
    empathy enhancement
    Euphoria / Mood Elevation ×2
    5
    euphoria emotion enhancement
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    8
    tactile enhancement colour enhancement visual enhancement

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 2C-B-FLY-NBOMe there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "2C-B-FLY-NBOMe (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    2C-B-FLY-NBOMe
    Unit
    Β΅g
    Description
    2C-B-FLY-NBOMe
    Source: SubstanceSearch (substancesearch.com)
    
    Sublingual dose (Β΅g): threshold 75-150 Β· light 150-300 Β· common 300-600 Β· strong 600-900 Β· heavy 900+
    Buccal dose (Β΅g): threshold 100-200 Β· light 200-350 Β· common 350-650 Β· strong 650-950 Β· heavy 950+
    Insufflated dose (Β΅g): threshold 100-200 Β· light 200-400 Β· common 400-700 Β· strong 700-900 Β· heavy 900+
    
    Sublingual duration: onset 10-40m Β· come-up 0.5-1h Β· peak 2-4h Β· offset 3-5h Β· total 5.67-10.67h Β· after-effects 4-12h
    Buccal duration: onset 10-40m Β· come-up 0.5-1h Β· peak 2-4h Β· offset 3-5h Β· total 5.67-10.67h Β· after-effects 4-12h
    Insufflated duration: onset 5-15m Β· come-up 20-40m Β· peak 2-4h Β· offset 3-5h Β· total 5.41-9.92h Β· after-effects 4-12h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 450 Β΅g (Sublingual).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 2d Half tolerance 7d Baseline ~14d

    Rapid 5‑HT2A desensitization produces short-term tachyphylaxis (hours–days). Functional tolerance typically halves within ~1 week and returns to near-baseline by 2–3 weeks; cross-tolerance with other classic psychedelics is expected but not fully quantified.

    Cross-Tolerances

    Effects dose.wiki

    Positive
    • Stimulation
    Negative
    • Vasoconstriction
    • Teeth grinding
    • Pupil dilation
    • Increased heart rate
    • Nausea
    • Temperature regulation suppression
    Neutral
    • Mouth numbing
    • Sedation
    • Spontaneous bodily sensations
    Positive
    • Euphoria
    • Thought connectivity
    • Introspection
    • Analysis enhancement
    • Conceptual thinking
    • Emotion enhancement
    • Empathy enhancement
    • Wakefulness
    Negative
    • Anxiety
    Neutral
    • Time distortion
    Positive
    • Visual enhancement
    • Pattern recognition enhancement
    • Colour enhancement
    • Tracers
    • Tactile enhancement
    • Auditory enhancement
    • Synaesthesia
    • Colour shifting
    Neutral
    • Geometric patterns
    • Drifting

    Combinations

    Cross-Check 2C-B-FLY-NBOMe with another substance

    Helpful Links