Summary
At sub-psychedelic doses (10 mg or less), 2C-D has been explored as a cognitive enhancer or 'smart drug', though results vary. Shulgin called it 'pharmacological tofu' for its ability to extend or potentiate other substances without strongly coloring the experience. The dose-response curve is steep; use volumetric dosing and a milligram scale. MAOIs potentiate 2C-D significantly and can cause dangerous interactions. Set and setting remain crucial for positive outcomes.
Perspectives
“There is something going on, but it is subtle. I find that I can just slightly redirect my attention so that it applies more exactly to what I am doing. I feel that I can learn faster. This is a ‘smart’ pill!”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-25mg | 25-50mg | 50-100mg | 100mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 15-45 min | 19-40 min | 1.5-2.5 hrs | 30-90 min | 1.0-4.0 hrs | 3.5-5.0 hrs |
| Insufflated | 4-15 min | 15-30 min | 1.5-2.5 hrs | 30-90 min | 1.0-4.0 hrs | 3.0-5.0 hrs |
Tolerance
Effects
- Stimulation
- Creativity Enhancement
- Mental and physical stimulation
- Spontaneous tactile sensations
- Pupil dilation
- Increased heart rate
- Stomach discomfort
- Headache
- Nausea
- Temperature regulation suppression
- Sedation
- Spontaneous bodily sensations
- Thought Connectivity
- Analysis Enhancement
- Cognitive Clarity
- Conceptual Thinking
- Mood lift
- Euphoria
- Cognitive enhancement
- Increased mental clarity and interest
- Feelings of empathy
- Sociability
- Introspection
- Giggling
- Emotion enhancement
- Novelty enhancement
- Unity and interconnectedness
- Increased sense of humor
- Increased introspection
- Dizziness
- Anxiety
- Memory suppression
- Time Distortion
- Changes in perception of time
- Personal bias suppression
- Perspective alterations
- Thought acceleration
- Recursion
- Existential self-realization
- Emotion intensification
- Bodily Control Enhancement
- Tactile Enhancement
- Color Enhancement
- Pattern Recognition Enhancement
- Visual Acuity Enhancement
- Synaesthesia
- Enhanced tactile sensation
- Sensory enhancement
- Brightened colors
- Acuity enhancement
- Auditory enhancement
- Colour enhancement
- Colour shifting
- Tracers
- Increased music appreciation
- Color shifting
- Auditory acuity enhancement
- Dehydration
- Spontaneous Physical Sensations
- Drifting
- Internal Hallucination
- External Hallucination
- Auditory Distortion
- Auditory hallucinations
- Autonomous entities
- External hallucinations
- Internal hallucinations
- Auditory hallucination
- Diffraction
- Symmetrical texture repetition
- Autonomous entity
- After images
- Color tinting
- Perspective hallucination
- Tactile intensification
Combinations
Trip Reports
PiHKAL / TiHKAL
“There is something going on, but it is subtle. I find that I can just slightly redirect my attention so that it applies more exactly to what I am doing. I feel that I can learn faster. This is a ‘smart’ pill!”