4-Fluorodeprenyl
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 1 source
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Fludepryl, Sr-96516-a, Chinoin-175, P-f-deprenyl, P-fluoro-l-deprenyl
Summary
Metabolizes to 4-fluoroamphetamine and 4-fluoromethamphetamine, which may add dopaminergic load and extend duration. Risk of serotonin syndrome when combined with serotonergic drugs. At higher doses (>10 mg) selectivity for MAO-B diminishes, increasing dietary tyramine risk and potential for non-selective MAO inhibition.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-2mg | 2-5mg | 5-10mg | 10mg+ |
| Sublingual | 0.5-1mg | 1-3mg | 3-6mg | 6mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-60 min | 2-4 hrs | 4-8 hrs | 4-8 hrs |
| Sublingual | 30-60 min | 2-4 hrs | 4-8 hrs | 4-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate focus and anxiety/jitters with mild stimulation and euphoria
Tolerance
Tolerance Decay
Irreversible MAO‑B inhibition recovers via enzyme resynthesis over days to weeks, not by drug clearance; subjective stimulant tolerance appears limited, but functional interactions persist for 24–48 h post‑dose. Values are heuristic, based on MAOI pharmacology rather than direct human datasets for this analog.
Cross-Tolerances
Effects
- Stimulation
- Physical fatigue reduction
- Reduced fatigue
- Insomnia
- Increased heart rate
- Slight appetite suppression
- Occasional insomnia
- Headaches
- Nausea
- Headache
- Euphoria
- Focus enhancement
- Motivation enhancement
- Wakefulness
- Sociability enhancement
- Subtle mental alertness
- Enhanced motivation
- Mild euphoria
- Anxiety
- Thought acceleration
- Increased libido
- Libido enhancement
- Increased music appreciation
- Increased Music Appreciation
- Appetite suppression
- Light sensitivity
- Dehydration
- Photophobia
- Appetite Suppression
- Spontaneous physical sensations
Combinations
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