4-Fluorodeprenyl
Aliases: Fludepryl, Sr-96516-a, Chinoin-175, P-f-deprenyl, P-fluoro-l-deprenyl
Categories
Summary
Metabolizes to 4-fluoroamphetamine and 4-fluoromethamphetamine, which may add dopaminergic load and extend duration. Risk of serotonin syndrome when combined with serotonergic drugs. At higher doses (>10 mg) selectivity for MAO-B diminishes, increasing dietary tyramine risk and potential for non-selective MAO inhibition. Use accurate mg-scale for dosing. Contraindicated in individuals with cardiovascular disease.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 30-60 min | 1-2 hrs | 2-4 hrs | 4-8 hrs | 24-48 hrs |
| Sublingual | 15-30 min | 30-90 min | 2-4 hrs | 4-8 hrs | 24-48 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Physical fatigue reduction
- Reduced fatigue
Negative
- Insomnia
- Increased heart rate
- Slight appetite suppression
- Occasional insomnia
- Headaches
- Nausea
- Headache
Positive
- Euphoria
- Focus enhancement
- Motivation enhancement
- Wakefulness
- Sociability enhancement
- Subtle mental alertness
- Enhanced motivation
- Mild euphoria
Negative
- Anxiety
- Thought acceleration
Positive
- Increased libido
- Libido enhancement
- Increased music appreciation
- Increased Music Appreciation
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Photophobia
- Appetite Suppression
- Spontaneous physical sensations