4-Fluoropentedrone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- 3 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: 4-fpd, 4-f-pentedrone, 4-fluoro-alpha-methylamino-valerophenone, 4f-pentedrone
Summary
4-Fluoropentedrone (4-FPD) is a synthetic cathinone sold on the gray market since approximately 2018. Human pharmacology remains largely uncharacterised; harm-reduction advice is extrapolated from pentedrone and 4-FMC data plus limited community reports. Acute risks include tachycardia, hypertension, vasoconstriction, hyperthermia, diaphoresis, agitation, bruxism, mydriasis, anxiety, and panic.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-40mg | 40-80mg | 80-120mg | 120mg+ |
| Insufflated | 10-25mg | 25-60mg | 60-90mg | 90mg+ |
| Rectal | 15-30mg | 30-60mg | 60-90mg | 90mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 10-30 min | 1-2 hrs | 1-2 hrs | 2-4 hrs |
| Insufflated | 2-5 min | 1-2 hrs | 1-2 hrs | 2-4 hrs |
| Rectal | 5-10 min | 1-2 hrs | 1-2 hrs | 2-4 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate euphoria and focus, low stimulation
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal patterns suggest rapid tolerance with binge/redosing across 1โ2 days, partial decay over 3โ7 days, and nearโbaseline by ~2 weeks. Data quality is low and varies widely among individuals.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Increased blood pressure
- Vasoconstriction
- Increased perspiration
- Bruxism
- Temperature regulation suppression
- Temporary erectile dysfunction
- Urinary retention
- Insomnia
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
- Increased sociability
- Anxiety
- Compulsive redosing
- Paranoia
- Cognitive fatigue
- Depression
- Anhedonia
- Thought acceleration
- Increased music appreciation
- Tactile enhancement
- Color enhancement
- Brightened colour
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Drifting
Combinations
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