4-Fluoropentedrone
Aliases: 4-fpd, 4-f-pentedrone, 4-fluoro-alpha-methylamino-valerophenone, 4f-pentedrone
Summary
4-Fluoropentedrone (4-FPD) is a synthetic cathinone sold on the gray market since approximately 2018. Human pharmacology remains largely uncharacterised; harm-reduction advice is extrapolated from pentedrone and 4-FMC data plus limited community reports. Acute risks include tachycardia, hypertension, vasoconstriction, hyperthermia, diaphoresis, agitation, bruxism, mydriasis, anxiety, and panic.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 10-30 min | 15-30 min | 1-2 hrs | 1-2 hrs |
| Insufflated | 2-5 min | 5-10 min | 1-2 hrs | 1-2 hrs |
| Rectal | 5-10 min | 10-20 min | 1-2 hrs | 1-2 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate euphoria and focus, low stimulation
Tolerance
Tolerance Decay
Anecdotal patterns suggest rapid tolerance with binge/redosing across 1–2 days, partial decay over 3–7 days, and near‑baseline by ~2 weeks. Data quality is low and varies widely among individuals.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Increased blood pressure
- Vasoconstriction
- Increased perspiration
- Bruxism
- Temperature regulation suppression
- Temporary erectile dysfunction
- Urinary retention
- Insomnia
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
- Increased sociability
- Anxiety
- Compulsive redosing
- Paranoia
- Cognitive fatigue
- Depression
- Anhedonia
- Thought acceleration
- Increased music appreciation
- Tactile enhancement
- Color enhancement
- Brightened colour
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Drifting