4-Fluoropentedrone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: 4-fpd, 4-f-pentedrone, 4-fluoro-alpha-methylamino-valerophenone, 4f-pentedrone
Summary
4-Fluoropentedrone (4-FPD) is a synthetic cathinone sold on the gray market since approximately 2018. Human pharmacology remains largely uncharacterised; harm-reduction advice is extrapolated from pentedrone and 4-FMC data plus limited community reports. Acute risks include tachycardia, hypertension, vasoconstriction, hyperthermia, diaphoresis, agitation, bruxism, mydriasis, anxiety, and panic.
Dose Information
Dose basis. Ranges are extrapolated from closely related cathinones and limited user reports; potency and salt form (usually HCl) can markedly change the effective dose. Start with an allergy test (1–2 mg) and a very small test dose (5–10 mg), then wait a full 2–3 h before considering more. Evidence quality: anecdotal/harm-reduction orgs. Intranasal use increases cardiovascular spikes and nasal injury. Finely crush, use your own clean straw, and rinse with 0.9% saline before/after; rotate nostrils and take breaks. Evidence: harm-reduction org guidance on snorting risks. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-40mg | 40-80mg | 80-120mg | 120mg+ |
| Insufflated | 10-25mg | 25-60mg | 60-90mg | 90mg+ |
| Rectal | 15-30mg | 30-60mg | 60-90mg | 90mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 10-30 min | 15-30 min | 1-2 hrs | 1-2 hrs | 2.42-5 hrs |
| Insufflated | 2-5 min | 5-10 min | 1-2 hrs | 1-2 hrs | 2.11-4.25 hrs |
| Rectal | 5-10 min | 10-20 min | 1-2 hrs | 1-2 hrs | 2.25-4.5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate euphoria and focus, low stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-Fluoropentedrone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
4-Fluoropentedrone Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 10-20 · light 20-40 · common 40-80 · strong 80-120 · heavy 120+ Insufflated dose (mg): threshold 5-10 · light 10-25 · common 25-60 · strong 60-90 · heavy 90+ Rectal dose (mg): threshold 8-15 · light 15-30 · common 30-60 · strong 60-90 · heavy 90+ Oral duration: onset 10-30m · come-up 15-30m · peak 1-2h · offset 1-2h · total 2.42-5h · after-effects 2-6h Insufflated duration: onset 2-5m · come-up 5-10m · peak 1-2h · offset 1-2h · total 2.11-4.25h · after-effects 2-6h Rectal duration: onset 5-10m · come-up 10-20m · peak 1-2h · offset 1-2h · total 2.25-4.5h · after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 60 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal patterns suggest rapid tolerance with binge/redosing across 1–2 days, partial decay over 3–7 days, and near‑baseline by ~2 weeks. Data quality is low and varies widely among individuals.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Increased blood pressure
- Vasoconstriction
- Increased perspiration
- Bruxism
- Temperature regulation suppression
- Temporary erectile dysfunction
- Urinary retention
- Insomnia
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
- Increased sociability
- Anxiety
- Compulsive redosing
- Paranoia
- Cognitive fatigue
- Depression
- Anhedonia
- Thought acceleration
- Increased music appreciation
- Tactile enhancement
- Color enhancement
- Brightened colour
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Drifting
Combinations
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