5-APDI
Aliases: Iap, 2-api, 5-iap, Indanametamine, Indanylamphetamine
Categories
Summary
5-APDI (IAP) is a potent but weakly selective serotonin-releasing agent with IC50 values of 82 nM for serotonin, 1,848 nM for dopamine, and 849 nM for norepinephrine. Users report empathogenic warmth, mental stimulation, and occasionally mild visuals, but also pronounced body-load including hyperthermia, profuse sweating, bowel urgency, bruxism, and insomnia. Onset is slow; premature redosing has produced serotonin syndrome-like reactions. Cardiovascular stress and unpredictable individual response make conservative titration and external temperature control essential. Milligram-scale weighing and reagent testing are strongly advised.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 15-25mg | 25-50mg | 50-75mg | 75mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 30-90 min | 2-5 hrs | 3-6 hrs | 1-6 hrs |
| Insufflated | 5-15 min | 2-4 hrs | 2-4 hrs | 1-6 hrs |
| Intravenous | 1-5 min | 2-4 hrs | 2-4 hrs | 1-6 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Increased energy/alertness
Negative
- Teeth grinding
- Diarrhea
- Excessive perspiration
- Pupil dilation
- Nystagmus
- Insomnia
- Weight loss
- Sweating
- Gastrointestinal discomfort
- Decreased need for sleep
- Decreased appetite
- Distrubed sleep patterns
- Bruxia
Positive
- Euphoria
- Increased sociability
- Empathy enhancement
- Mood lift
- Wakefulness
Negative
- Anxiety
- Agressiveness
- Excessive talking
- Moodiness
- Talkativeness
Positive
- Music enhancement
- Visual enhancement
- Tracers
- Increased music appreciation
Negative
- Dehydration
- Light sensitivity
- Appetite suppression
- Increase sexuality
- Visual and audiotory hallucinations itchiness
- Increased sexuality