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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MAPB

    Aliases: 5mapb

    Categories

    Psychedelic Stimulant Empathogen Research-chemical
    5-MAPB structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    5-MAPB is a potent non-selective monoamine releaser with approximately 3-5 times the potency of MDMA at serotonin and norepinephrine transporters. It functions as a full 5-HT2B receptor agonist, which suggests potential cardiac valve toxicity with repeated use; spacing sessions at least 4-6 weeks apart is strongly advised. Significant batch-to-batch variability in potency has been documented; always use reagent testing and start with a low dose. The hydrochloride salt is 36% more potent by mass than the succinate salt. Common adverse effects include hyperthermia, hypertension, tachycardia, and jaw clenching.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 40-60mg 60-80mg 80-100mg 100mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 45-90 min 2.0-4.0 hrs 1.5-3.0 hrs 6.0-48.0 hrs 5.0-8.0 hrs
    Insufflated 4-19 min 19-40 min 2.0-4.0 hrs 1.5-3.0 hrs 6.0-48.0 hrs 5.0-8.0 hrs
    Rectal 15-40 min 30-60 min 2.0-4.0 hrs 1.5-3.0 hrs 6.0-48.0 hrs 5.0-8.0 hrs
    Intramuscular 10-30 min 19-40 min 2.0-4.0 hrs 1.5-3.0 hrs 6.0-48.0 hrs 5.0-8.0 hrs

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline
    Cross-tolerance
    LSD Psilocybin Psilocin Mescaline DMT 5-MeO-DMT 2C-B 2C-E

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Increased energy/alertness
    Negative
    • Nystagmus
    • Teeth grinding
    • Vasoconstriction
    • Increased perspiration
    • Increased heart rate
    • Temporary erectile dysfunction
    • Weight loss
    • Sweating
    • Nausea
    Neutral
    • Increased body temperature
    • Decreased need for sleep
    • Decreased appetite
    • Distrubed sleep patterns
    • Bruxia
    Positive
    • Cognitive euphoria
    • Empathy enhancement
    • Increased sociability
    • Wakefulness
    • Euphoria
    • Mood lift
    • Empathy, affection and sociability enhancement
    • Motivation enhancement
    • Memory enhancement
    • Analysis enhancement
    Negative
    • Anxiety
    • Cognitive fatigue
    • Depression
    • Motivation suppression
    • Thought deceleration
    • Agressiveness
    • Irritability
    • Compulsive redosing
    • Motivation depression
    Neutral
    • Time distortion
    • Excessive talking
    • Moodiness
    • Thought acceleration
    • Focus intensification
    Positive
    • Tactile enhancement
    • Music enhancement
    • Visual acuity enhancement
    • Colour enhancement
    • Increased music appreciation
    Negative
    • Appetite suppression
    • Dehydration
    Neutral
    • Increase sexuality
    • Visual and audiotory hallucinations itchiness
    • Vibrating vision

    Combinations TripSit

    Helpful Links

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