5-MeO-AMT - Substance Search

Summary TheDrug.Wiki Erowid TripSit

One of the most potent psychedelic tryptamines known, requiring extreme caution with dosing. Highly dose-sensitive with medical emergencies reported at doses as low as 8 mg oral. Has been misrepresented as LSD on blotter and gelatin tabs, leading to multiple hospitalizations and deaths.

Dose Information TheDrug.Wiki TripSit

ROA	Light	Common	Strong	Heavy
Oral	1-2mg	2-4mg	4-6mg	6mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit

ROA	Onset	Comeup	Peak	Offset	After Effects
Oral	0.5-2 hrs	1-2 hrs	3-8 hrs	3-6 hrs	4-24 hrs
Insufflated	4-19 min	19-40 min	3-8 hrs	3-6 hrs	4-24 hrs
Rectal	4-19 min	30-60 min	3-8 hrs	3-6 hrs	4-24 hrs

Effect Profile

144 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Validated against 136 Erowid trip reports
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 6.5

Strong 6/10

Strong visuals, auditory effects, and body load with mild headspace

Visual Intensity ×3

10

color enhancement pattern recognition enhancement brightened colour

Headspace Depth ×3

4

confusion

Auditory Effects ×1

10

auditory enhancement

⚠ Body Load / Somatic Effects ×1

10

temperature regulation suppression nausea muscle tension jaw clenching

Empathogen 9.4

Intense+ 9/10

Strong empathy, stimulation, sensory enhancement, and euphoria

Empathy / Social Openness ×3

10

empathy enhancement empathy sociability enhancement

Euphoria / Mood Elevation ×2

8

euphoria mood elevation

Stimulation ×1

10

physical stimulation mental stimulation restlessness

Sensory Enhancement ×1

10

tactile enhancement enhanced tactile sensation color enhancement

Stimulant 5.8

Strong 6/10

Strong anxiety/jitters, stimulation, and euphoria with low focus

Stimulation / Energy ×3

8

physical stimulation mental stimulation

Euphoria / Mood Lift ×2

8

euphoria mood elevation

Focus / Productivity ×2

3

⚠ Anxiety / Jitters ×1

10

anxiety restlessness jaw clenching muscle tension

Based on reports from:

Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 5-MeO-AMT

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 0h Half tolerance 3d Baseline ~10d

Animal data show rapid tolerance to head-twitch with repeated dosing; users commonly report diminished effects for several days after use with partial recovery by ~3 days and near-baseline after ~10–14 days. Cross-tolerance with classic psychedelics is expected given shared 5‑HT2A agonism, but human quantification is lacking.

Cross-Tolerances

LSD

50%

Psilocybin

50%

DMT

40%

Effects Erowid Bluelight

Aggregated from 136 Erowid and 8 Bluelight experience reports

Positive Effects 32

Visual Distortions 74.3% 80%

Brightness Enhancement 37.5% 87%

Melting/flowing 37.5% 83%

Thought Acceleration 37.5% 80%

Surface Breathing 37.5% 85%

Patterning 37.5% 83%

Stimulation 35.4% 81%

Euphoria 32.6% 86%

Music Enhancement 31.2% 90%

Color Enhancement 30.5% 84%

Tactile Enhancement 27.1% 80%

Visual Trails 25.0% 88%

Joy 25.0% 80%

Geometric Imagery 25.0% 82%

Awe 25.0% 78%

Auditory-Visual Synesthesia 25.0% 82%

Focus Enhancement 18.7% 75%

Empathy 18.7% 80%

Body High 15.3% 85%

Tessellation 12.5% 80%

Adverse Effects 45

Body Load 62.5% 81%

Nausea 57.0% 87%

Anxiety 41.6% 78%

Vomiting 37.5% 92%

Diarrhea 37.5% 82%

Insomnia 37.5% 88%

Dizziness 25.0% 90%

Depersonalization 25.0% 82%

Confusion 21.3% 70%

Headache 20.2% 75%

Auditory Effects 18.7% 90%

Open-Eye Visuals 13.2% 75%

Muscle Tension 13.2% 70%

Dry Mouth 12.5% 75%

Stomach Cramps 12.5% 75%

Thought Disorganization 12.5% 75%

Body Temperature Change 12.5% 70%

Chills 12.5% 80%

Focus Suppression 12.5% 80%

Sociability Suppression 12.5% 75%

Combinations TripSit

5-MeO-AMT's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

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