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    DMT

    Aliases: Dmitry, Dimitri, N,n-dmt, Fantasia, The glory, dimethyltryptamine

    Summary PsychonautWiki

    N,N-Dimethyltryptamine (also known as DMT, N,N-DMT, Dmitri, and "The Spirit Molecule") is a classical psychedelic substance of the tryptamine class. Among psychedelics, it is known for its unique ability to produce short-lived but intense visionary states and complete hallucinations. It is thought to produce its effects by binding to serotonin receptors in the brain, although the precise mechanism is not fully understood.

    Perspectives

    “As I exhaled I became terribly afraid, my heart very rapid and strong, palms sweat. A terrible sense of dread and doom filled me — I knew what was happening, I knew I couldn't stop it, but it was so overwhelming as to be almost unbearable. I lay down and dimmed the lights. Then the visions began. And what can be said about them?”

    “DMT creates an actual place rather than pattern distortions. I was transplanted into an unknown setting, which appeared to comprise some sort of other-reality. At some point in the future I will be drawn to another attempt.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Smoked BA ~100% 10-20mg 20-40mg 40-60mg 60mg+
    Insufflated BA ~60% 10-25mg 25-50mg 50-125mg 125mg+
    Intravenous 4-10mg 10-15mg 15-20mg 20mg+
    Vapourized 10-15mg 15-25mg 25-35mg 35mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Smoked 15 - 60 seconds - 1 - 5 minutes 5 - 10 minutes 10 - 60 minutes 15 - 90 minutes
    Oral 30-45 min 45-60 min 2-3 hrs 1-2 hrs 4-4 hrs -
    Insufflated 3-4 min - 45-60 min 10-20 min 15-60 min -
    Vapourized 0-1 min - 3-10 min 1-6 min 15-60 min 6-18 min

    Effect Profile

    1,292 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 1,043 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 9.1
    Intense+ 9/10

    Strong visuals, headspace, and auditory effects with mild body load

    Visual Intensity ×3
    10
    external hallucinations internal hallucinations autonomous entities colour enhancement drifting tracers +5 more

    “I sat up at the edge of the bed and opened my eyes, distortions such as visual drifting along with geometric patterns still covered my whole field of vision.”

    Alex effectindex

    “I could see around the room everything was moving on the surface but there were no closed eye visuals other than the swirling purple clouds going down the drain which is what I've always seen with my...”

    biffhenderson bluelight
    Headspace Depth ×3
    10
    conceptual thinking recursion subconscious communication emotion enhancement perspective alterations personal bias suppression +1 more

    “Complete and utter ego death hits.”

    Kaylee effectindex

    “At this point I experienced total ego death.”

    Alex effectindex
    Auditory Effects ×1
    8
    auditory distortions auditory hallucinations auditory distortion auditory enhancement

    “At about 90 seconds I started hearing a powerful sound that was not coming from the ears.”

    biffhenderson bluelight

    “Started with ringing ears, I never had that from DMT or 5-MeO-DMT before, just with I.M.”

    Solipsis bluelight
    Body Load / Somatic Effects ×1
    5
    temperature regulation suppression nausea vasoconstriction bodily pressures stomach discomfort

    “I am sweating and shaking a little.”

    Kaylee effectindex

    “The slight dizziness and nausea lasted a few hours.”

    biffhenderson bluelight

    User Experience

    visuals “I sat up at the edge of the bed and opened my eyes, distortions such as visual drifting along with geometric patterns still covered my whole field of vision.” — Alex, effectindex

    Tolerance

    Build-up minimal with single or spaced use; rapid with repeated dosing in one session
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 0.5h Half tolerance 0d Baseline ~1d

    Human studies found minimal to no rapid psychological tolerance after closely spaced IV administrations compared to other psychedelics; subjective effects remained robust, although some biological measures declined across repeated doses. Community reports suggest the ability to redose within a session with little tolerance, but cumulative physiological/psychological load increases. Data quality is mixed; cross-tolerance with other 5‑HT2A psychedelics is presumed but not well quantified.

    Cross-Tolerances

    LSD
    50%
    mescaline
    30%

    Effects Erowid Bluelight

    Aggregated from 1,043 Erowid and 249 Bluelight experience reports

    Positive Effects 73

    Entity Imagery 68.0% 90%
    Color Enhancement 62.8% 87%
    Awe 42.0% 86%
    Geometric Imagery 40.0% 88%
    Empathy 38.8% 80%
    Insight 38.0% 83%
    Euphoria 35.3% 88%
    Closed-Eye Visuals 34.4% 91%
    Music Enhancement 30.2% 86%
    Tactile Enhancement 26.6% 70%
    Focus Enhancement 25.9% 70%
    Revelatory Insight 24.0% 86%
    Mystical Quality 24.0% 89%
    Fractal Imagery 24.0% 92%
    Introspection 20.3% 83%
    Morphing 20.0% 87%
    Wonder 18.0% 84%
    Peace 18.0% 86%
    Body High 16.8% 85%
    Environmental Transfiguration 16.0% 88%

    Adverse Effects 29

    Anxiety 53.7% 84%
    Fear 36.0% 84%
    Confusion 28.7% 82%
    Body Load 24.0% 77%
    Depersonalization 24.0% 80%
    Panic 14.0% 86%
    Memory Suppression 10.2% 82%
    Pressure 8.0% 82%
    Nausea 7.4% 76%
    Thought Disorganization 6.0% 80%
    Increased Heart Rate 5.4% 70%
    Taste Distortion 4.0% 88%
    Vomiting 4.0% 88%
    Dread 4.0% 95%
    Muscle Tension 3.7% 70%
    Psychosis 3.3% 70%
    Thought Loops 3.0% 78%
    Sweating 2.7% 85%
    Jaw Clenching 2.4% 70%
    Pupil Dilation 2.2% 70%

    Combinations TripSit

    Trip Reports Effect Index

    PiHKAL / TiHKAL Shulgin

    TiHKAL #6: DMT

    “As I exhaled I became terribly afraid, my heart very rapid and strong, palms sweat. A terrible sense of dread and doom filled me — I knew what was happening, I knew I couldn't stop it, but it was so overwhelming as to be almost unbearable. I lay down and dimmed the lights. Then the visions began. And what can be said about them?”

    — Alexander Shulgin, TiHKAL (with 100 mg, smoked)

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