Summary
Bufotenin is a naturally occurring tryptamine found in Anadenanthera (Yopo/Cebil) seeds and in the parotoid glands of certain Bufo and Incilius toads. The Colorado River toad (Incilius alvarius) contains primarily 5-MeO-DMT, not bufotenin, and 'toad-licking' is extremely dangerous due to cardiotoxic bufadienolides in the venom. Pure bufotenin freebase vaporizes at approximately 160°C; use low-temperature glass pipes or e-mesh devices to minimize harshness. The substance produces marked peripheral vasoconstriction, flushing, tachycardia, and has been associated with bronchospasm, especially at doses above 40 mg or when administered intravenously. Individuals with asthma, hypertension, or cardiovascular conditions should avoid use.
Perspectives
“Within a minute (from the start of the injection) I had a tight feeling in my chest and my face felt as if it had been jabbed by nettles and this lasted for about 6 minutes. I had fleeting nausea.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Smoked | 5-20mg | 20-40mg | 40-60mg | 60mg+ |
| Insufflated | ~50-100mg(seeds,pulverized) | - | - | - |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Smoked | 0-1 min | 0-1 min | 1-5 min | 5-10 min | 10-60 min |
| Insufflated | 2-10 min | 5-15 min | 20-40 min | 30-60 min | 30-90 min |
| Sublingual | 5 min | 10-20 min | 35-40 min | 30-60 min | 30-90 min |
| Oral | 30-60 min | 30-60 min | 1-2 hrs | 1-2 hrs | 2-6 hrs |
Tolerance
Effects
- Physical euphoria
- Spontaneous tactile sensations
- Creativity enhancement
- Bodily pressures
- Skin flushing
- Vasoconstriction
- Temperature regulation suppression
- Pupil dilation
- Nausea
- Stomach discomfort
- Feelings of unity and interconnectedness
- Emotion enhancement
- Conceptual thinking
- Motor control loss
- Thought loops
- Anxiety
- Memory suppression
- Recursion
- Time distortion
- Consciousness disconnection
- Tactile enhancement
- Bodily control enhancement
- Visual acuity enhancement
- Color enhancement
- Color shifting
- Visual acuity suppression
- Perception of bodily heaviness
- Drifting
- Environmental orbism
- Auditory distortion
- Visual hallucinations
- Morphing
- Auditory distortions
Combinations
PiHKAL / TiHKAL
“Within a minute (from the start of the injection) I had a tight feeling in my chest and my face felt as if it had been jabbed by nettles and this lasted for about 6 minutes. I had fleeting nausea.”