Summary
2'-Oxo-PCM (also known as deschloroketamine, O-PCM, DXE, and DCK) is a lesser-known novel dissociative substance of the arylcyclohexylamine class that produces dissociative, anesthetic and hallucinogenic effects when administered.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated BA ~50% | 10-15mg | 15-25mg | 25-40mg | 40mg+ |
| Oral BA ~40% | 10-20mg | 20-30mg | 30-50mg | 50mg+ |
| Smoked | 5-10mg | 10-20mg | 20-40mg | 40mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Insufflated | 6-12 min | 30-60 min | 1.5-2.5 hrs | 1.0-2.0 hrs | 3.0-24.0 hrs | 3.0-6.0 hrs |
| Oral | 12-30 min | 30-60 min | 1.5-2.5 hrs | 1.0-2.0 hrs | 3.0-24.0 hrs | 3.0-6.0 hrs |
| Smoked | - | - | - | - | 1.0-8.0 hrs | 3.0-6.0 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Effects
Positive
- Stimulation
- Physical euphoria
- Pain relief
- Analgesia
Negative
- Numbness
- Loss of balance
- Nausea
- Increased heart rate
- Physical disconnection
- Sedation
Positive
- Cognitive euphoria
- Conceptual thinking
Negative
- Depersonalization
- Derealization
- Motor control loss
- Amnesia
- Memory suppression
- Cognitive disconnection
- Disconnection
- Time distortion
Positive
- Increased music appreciation
- Tactile enhancement
Negative
- Derealization
- Disinhibition
- Tactile suppression
- Spatial disorientation
- Double vision
- Pattern recognition suppression
- Visual disconnection
- Auditory distortion