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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methylone

    Aliases: M1, Mdmc, Ease, Bk-mdma, Explosion

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    3,4-Methylenedioxy-N-methcathinone (also known as M1, MDMC, ฮฒk-MDMA, and Methylone) is a novel stimulant-entactogen substance of the cathinone class. Methylone was first synthesized by chemists Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant. Methylone is sometimes used as a substitute for MDMA due to similarities in their effects.

    Perspectives

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 75-150mg 150-225mg 225-325mg 325mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 15-45 min 60-90 min 60-90 min 6-24 hrs 2-4 hrs

    Effect Profile

    228 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 167 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 9.7
    Extreme 10/10

    Strong empathy, stimulation, sensory enhancement, and euphoria

    Empathy / Social Openness ×3
    10
    empathy enhancement empathy, love, and sociability enhancement sociability enhancement
    Euphoria / Mood Elevation ×2
    9
    cognitive euphoria
    Stimulation ×1
    10
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement spontaneous tactile sensations increased libido
    Stimulant 7.5
    Intense 8/10

    Strong stimulation, anxiety/jitters, and euphoria with moderate focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    8
    cognitive euphoria
    Focus / Productivity ×2
    7
    analysis enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate

    Tolerance

    Build-up develops rapidly, similar to MDMA
    Reset 1โ€“3 months recommended

    Tolerance Decay

    Full tolerance 1h Half tolerance 60d Baseline ~90d

    Cross-Tolerances

    Empathogens
    MDMA
    80%
    MDA
    80%

    Effects Erowid Bluelight

    Aggregated from 167 Erowid and 61 Bluelight experience reports

    Positive Effects 67

    Euphoria 68.2% 91%
    Stimulation 55.3% 81%
    Empathy 52.5% 85%
    Music Enhancement 44.7% 83%
    Sociability Enhancement 30.0% 84%
    Tactile Enhancement 29.5% 86%
    Body High 26.3% 84%
    Sedation 26.2% 78%
    Love 26.0% 86%
    Introspection 24.4% 82%
    Color Enhancement 24.4% 81%
    Contentment 22.0% 84%
    Tingling 20.0% 82%
    Emotional Openness 18.0% 86%
    Focus Enhancement 17.5% 82%
    Thought Acceleration 16.0% 79%
    Joy 14.0% 86%
    Empathogenic Connection 14.0% 85%
    Motor Enhancement 12.0% 78%
    Tactile Intimacy Enhancement 12.0% 82%

    Adverse Effects 58

    Anxiety 36.4% 81%
    Visual Distortions 28.5% 83%
    Jaw Clenching 28.1% 84%
    Insomnia 24.0% 83%
    Dysphoria 22.0% 83%
    Confusion 20.3% 80%
    Nausea 19.8% 77%
    Body Load 16.0% 80%
    Thought Disorganization 14.0% 78%
    Muscle Tension 13.8% 70%
    Auditory Effects 12.5% 84%
    Body Temperature Change 12.0% 81%
    Dry Mouth 10.0% 83%
    Headache 8.3% 80%
    Paranoid Ideation 8.0% 78%
    Dizziness 8.0% 80%
    Tremor 8.0% 79%
    Heart Rate Increase 6.0% 90%
    Muscle Spasm 6.0% 87%
    Fear 6.0% 87%

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #110: MDMC

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    โ€” Alexander Shulgin, PiHKAL (with 150 mg)

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