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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methylone Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 29 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: M1, Mdmc, Ease, Bk-mdma, Explosion

    Summary dose.wiki Erowid TripSit PsychonautWiki

    3,4-Methylenedioxy-N-methcathinone (also known as M1, MDMC, ฮฒk-MDMA, and Methylone) is a novel stimulant-entactogen substance of the cathinone class. Methylone was first synthesized by chemists Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant. Methylone is sometimes used as a substitute for MDMA due to similarities in their effects.

    Perspectives

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 75-150mg 150-225mg 225-325mg 325mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 15-45 min 60-90 min 60-90 min 6-24 hrs 2-4 hrs

    Effect Profile

    137 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 76 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 9.7
    Extreme 10/10

    Strong empathy, stimulation, sensory enhancement, and euphoria

    Empathy / Social Openness ×3
    10
    empathy enhancement empathy, love, and sociability enhancement sociability enhancement
    Euphoria / Mood Elevation ×2
    9
    cognitive euphoria
    Stimulation ×1
    10
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement spontaneous tactile sensations increased libido
    Stimulant 7.1
    Strong+ 7/10

    Strong stimulation and euphoria with strong anxiety/jitters, moderate focus

    Stimulation / Energy ×3
    9
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    9
    cognitive euphoria
    Focus / Productivity ×2
    6
    analysis enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate

    Tolerance

    No tolerance chart. No study has measured how long tolerance to it lasts, so this page shows what is known instead of a curve.

    No study has measured tolerance to methylone in people. PsychonautWiki estimates that tolerance halves in 1-3 weeks and is gone in 3-6 weeks, without citing a source.

    Sources: PsychonautWiki: methylone

    Cross-Tolerances

    Empathogens

    Effects Erowid Bluelight

    Aggregated from 76 single-substance Erowid and 61 Bluelight experience reports (the Bluelight figures come from the 50 of them read for effects); 91 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 66

    71.4% (95% interval 63 to 79 percent) 91%
    54.0% (95% interval 45 to 62 percent) 81%
    47.6% (95% interval 39 to 56 percent) 85%
    34.9% (95% interval 27 to 44 percent) 83%
    30.0% (95% interval 19 to 44 percent) 84%
    27.8% (95% interval 21 to 36 percent) 84%
    26.0% (95% interval 16 to 40 percent) 86%
    23.0% (95% interval 16 to 31 percent) 82%
    22.0% (95% interval 13 to 35 percent) 84%
    21.5% (95% interval 15 to 29 percent) 78%
    20.0% (95% interval 11 to 33 percent) 82%
    18.0% (95% interval 10 to 31 percent) 86%
    16.7% (95% interval 11 to 24 percent) 86%
    16.6% (95% interval 11 to 24 percent) 81%
    16.0% (95% interval 8 to 28 percent) 79%
    14.0% (95% interval 7 to 26 percent) 86%
    14.0% (95% interval 7 to 26 percent) 82%
    14.0% (95% interval 7 to 26 percent) 85%
    12.0% (95% interval 6 to 24 percent) 78%
    12.0% (95% interval 6 to 24 percent) 82%
    Show 46 more positive effects
    12.0% (95% interval 6 to 24 percent) 79%
    10.0% (95% interval 4 to 21 percent) 83%
    10.0% (95% interval 4 to 21 percent) 82%
    10.0% (95% interval 4 to 21 percent) 83%
    10.0% (95% interval 4 to 21 percent) 87%
    10.0% (95% interval 4 to 21 percent) 83%
    8.7% (95% interval 5 to 15 percent) 75%
    8.7% (95% interval 5 to 15 percent) 82%
    8.0% (95% interval 3 to 19 percent) 88%
    8.0% (95% interval 3 to 19 percent) 81%
    8.0% (95% interval 3 to 19 percent) 81%
    8.0% (95% interval 3 to 19 percent) 81%
    7.1% (95% interval 4 to 13 percent) 85%
    6.0% (95% interval 2 to 16 percent) 85%
    6.0% (95% interval 2 to 16 percent) 70%
    6.0% (95% interval 2 to 16 percent) 87%
    6.0% (95% interval 2 to 16 percent) 75%
    6.0% (95% interval 2 to 16 percent) 80%
    4.0% (95% interval 1 to 14 percent) 88%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 90%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 78%
    3.9% (95% interval 2 to 9 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 95%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%

    Adverse Effects 56

    28.5% (95% interval 21 to 37 percent) 81%
    27.0% (95% interval 20 to 35 percent) 84%
    24.0% (95% interval 14 to 37 percent) 83%
    22.0% (95% interval 13 to 35 percent) 83%
    18.2% (95% interval 12 to 26 percent) 77%
    16.0% (95% interval 8 to 28 percent) 80%
    14.0% (95% interval 7 to 26 percent) 78%
    13.5% (95% interval 9 to 20 percent) 80%
    13.5% (95% interval 9 to 20 percent) 83%
    13.2% (95% interval 7 to 23 percent) –
    12.0% (95% interval 6 to 24 percent) 81%
    Auditory Effects 10.3% (95% interval 6 to 17 percent) 84%
    10.0% (95% interval 4 to 21 percent) 83%
    8.0% (95% interval 3 to 19 percent) 78%
    8.0% (95% interval 3 to 19 percent) 80%
    8.0% (95% interval 3 to 19 percent) 79%
    6.4% (95% interval 3 to 12 percent) 80%
    6.0% (95% interval 2 to 16 percent) 90%
    6.0% (95% interval 2 to 16 percent) 87%
    6.0% (95% interval 2 to 16 percent) 87%
    Show 36 more adverse effects
    6.0% (95% interval 2 to 16 percent) 75%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 92%
    4.0% (95% interval 1 to 14 percent) 90%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 75%
    4.0% (95% interval 1 to 14 percent) 70%
    4.0% (95% interval 1 to 14 percent) 75%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 80%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 95%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 95%
    2.0% (95% interval 0 to 10 percent) 65%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) –
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 70%
    2.0% (95% interval 0 to 10 percent) 65%

    Also reported in combinations. In the 91 Methylone reports where another drug was taken too, 6 (6.6%) mention hospital, emergency services or an overdose, 3 (3.3%) a seizure and 4 (4.4%) psychosis. In the 76 single-substance reports: 7.9%, 1.3% and 2.6%. These are not in the figures above: they cannot be put down to Methylone alone, and a mention is not always something that happened to the writer.

    Combinations

    Cross-Check Methylone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 6 positive 2 neutral visit
    Euphoric and Extremely Peaceful positive exp #46340

    This is a report of my first experience with methylone. I had already had numerous experiences with magic mushrooms, pot, and beer, but that was the extent of my drug experiences. I was on a trip with a tour guide and 3 other people. One of them knew the guide, and the other two were a recently married couple.

    open · 170 mg oral
    A Wonderful Evening With Beautiful People positive exp #99233

    Dose: 150mg First, as a little context, my own experience. Over the last year and a half, I've drunk my share of alcohol, inhaled a ton of nitrous, smoked a bit of cannabis, despite the fact that it's never interested me particularly, dosed on acid six or seven times, my favorite thus far, and tried MDMA once.

    anonymous · 150 mg oral / 80 mg oral / 120 mg oral
    Unbelievably, Unexpectedly, Beautiful positive exp #79767

    This was only my second experience with methylone, but it was so personally remarkable that I felt it worth documenting. My first experience had been with a single 200mg dose, oral, a week prior to this one, and had been thoroughly pleasant, but I felt it could have been improved.

    DocApos · 4 glasses oral / 200 mg oral / 150 mg oral
    The Head and the Heart neutral exp #105042

    Previous experience: Ketamine, Cocaine, Benzos, Opiates, Cannabis, MDMA, MDA, DMT, LSD, Psilocybin, Amphetamine salts, Methamphetamine Other participant: TS2 is male, approximately 300lbs, and also an experienced and educated drug user.

    Tryptofan · 130 mg oral / 1 hit smoked / 60 mg insufflated / smoked
    The Feeling Within positive exp #53665

    Mindset: Very good mood, prepared for the experience Method of dosing: Capsule Dosage: 175mgs Duration: 4-5 hours Medications: None It had been a long time since I had experimented with Methylone, and I was finally graciously given the chance to experience that wonderful beauty in everything again, little did I know, I...

    Sepulfreak · 175 mg oral / smoked / smoked
    A Seeker's Best Friend positive exp #115572

    I am not an expert on the use of psychoactives. Iย’ve used LSD, psilocybic mushrooms, and Methyloneย’s cousins: MDA, MDMA a handful of times, but Iย’m no frequent flyer.

    Clear Fire · 200 mg oral
    I Didn't Want It To End positive exp #93379

    The only drug experience I've had were with cannabis and benzos. I used to smoke weed almost every night with my cousins, but I hated it. I always felt anxious, paranoid, and just terrible. I live with my boyfriend now, and he had recently experimented with MDMA and had a great time.

    karika
    A Valuable, Low Intensity Entheogen neutral exp #85287

    I discovered this compound while reading a website and decided to give it a try, given its legal status in the USA. I order it online and am surprised when it arrives from China in just over a week. It is shipped discreetly. I plan on giving this a try by myself first to discover dosages and effects.

    Entheonaut · 100 mg oral / 33 mg oral / 45 mg oral / 45 mg oral
    Bluelight 8 threads 4 positive 3 neutral 1 cautionary visit
    Methylone Experienced Getting To Know Her All Over Again positive

    June 2002 190 mg methylone It was the first night of camping in our month long tour of the American Southwest. My partner and I were staying at the Homolovi Ruins, a sacred place to the Hopi located just outside of Winslow, Arizona.

    Methylone Experienced The Feeling Within positive

    ''The Feeling Within'' Monday June 5th 2006 It had been a long time since I had experimented with Methylone, and I was finally graciously given the chance to experience that wonderful beauty in everything again; little did I know, I was about to have one the best experiences of my entire life.

    Methylone Exp The Collective Consciousness Experience neutral

    So I had a TRUE ++++ tonight from methylone. YES, methylone. None of this has any time stamps on it and it is quite long but trust me it is worth the read... Im still in awe of everything I saw and learned and experienced and felt...

    Methylone Retrospective Heart Chakra Express neutral

    Methylone. 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one. MDMCAT. have not written a trip report for awhile, but felt this substance deserves special mention, primarily for its psychotherapeutic value, which is substantial and differs from many other compounds i have sampled, said to be tools tailored for such...

    Methylone Inexp Light At The End Of The Tunnel positive

    Okay so here's the deal. I've had stuff that was labelled as methylone before but it was nowhere near this potent and it didn't have this much power to it. Therefore, I'm questioning if what I had wasn't really MBDB or some other related substance instead. Here's the set.

    Methylone Methyl 1 Mdmcat First Time Afterglow Tranquillity positive

    Methyl-1 (MDMCat) --- first time --- Afterglow Tranquillity Methylone (2-methylamino-1-[3,4-methylenedioxyphenyl]propan-1-one) Also known as Methylenedioxy-methcathinone (MDMCat). I call it Methyl-1 for short. Ate 100mg. It had a bitter chemical taste that reminded me a lot of the 2C-I I got from the same source.

    Methylone Semi Experienced Binging And Paying The Price neutral

    Ok, so I decided to try an give an account of what in retrospect I consider to be an extremely stupid and irresponsible indulgence in Methylone and 4-FA combined.... Within 3 days I went through roughly 2 grams of M1 and roughly 1 gram of 4-FA.

    Methylone Experienced Seizure And Near Death Experience cautionary

    Hey everyone, this is my first real attempt at writing one of these reports so be nice I would say that I am fairly experienced with mephedrone/methylone/butylone/mdma having used all of these on numerous occasions in the past (mdma being the compound of choice of course ), in the fortnight leading up to this event I k...

    300 mg mentioned in the thread; auto-extracted, unverified

    Bluelight Reference Guide Bluelight

    [MEGA] Cathinone Subthread - Methylone, ethylone, pentylone... Chemical alphabet soup

    Methylone This thread is mainly for Methylone, AKA BK-MDMA or 3,4-methylenedioxy-N-methylcathinone. It will also cover it's relative analogues, pentylone ethylone, butylone, and several others.

    Read full thread on Bluelight โ†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #110: MDMC

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    โ€” Alexander Shulgin, PiHKAL (with 150 mg)
    →

    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Methylone, but its built-in data can be thinner than ours. Importing this file adds a separate "Methylone (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.

    ⬇ Download import file Import this file as custom substances and you get "Methylone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.