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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methylone Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: M1, Mdmc, Ease, Bk-mdma, Explosion

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    3,4-Methylenedioxy-N-methcathinone (also known as M1, MDMC, ฮฒk-MDMA, and Methylone) is a novel stimulant-entactogen substance of the cathinone class. Methylone was first synthesized by chemists Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant. Methylone is sometimes used as a substitute for MDMA due to similarities in their effects.

    Perspectives

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 75-150mg 150-225mg 225-325mg 325mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 15-45 min 60-90 min 60-90 min 6-24 hrs 2-4 hrs

    Effect Profile

    228 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 167 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 9.7
    Extreme 10/10

    Strong empathy, stimulation, sensory enhancement, and euphoria

    Empathy / Social Openness ×3
    10
    empathy enhancement empathy, love, and sociability enhancement sociability enhancement
    Euphoria / Mood Elevation ×2
    9
    cognitive euphoria
    Stimulation ×1
    10
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement spontaneous tactile sensations increased libido
    Stimulant 7.5
    Intense 8/10

    Strong stimulation, anxiety/jitters, and euphoria with moderate focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    8
    cognitive euphoria
    Focus / Productivity ×2
    7
    analysis enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate

    Tolerance

    Build-up develops rapidly, similar to MDMA
    Reset 1โ€“3 months recommended

    Tolerance Decay

    Full tolerance 1h Half tolerance 60d Baseline ~90d

    Cross-Tolerances

    Empathogens
    MDMA
    80%
    MDA
    80%

    Effects Erowid Bluelight

    Aggregated from 167 Erowid and 61 Bluelight experience reports

    Positive Effects 67

    Euphoria 68.2% 91%
    Stimulation 55.3% 81%
    Empathy 52.5% 85%
    Music Enhancement 44.7% 83%
    Sociability Enhancement 30.0% 84%
    Tactile Enhancement 29.5% 86%
    Body High 26.3% 84%
    Sedation 26.2% 78%
    Love 26.0% 86%
    Introspection 24.4% 82%
    Color Enhancement 24.4% 81%
    Contentment 22.0% 84%
    Tingling 20.0% 82%
    Emotional Openness 18.0% 86%
    Focus Enhancement 17.5% 82%
    Thought Acceleration 16.0% 79%
    Joy 14.0% 86%
    Empathogenic Connection 14.0% 85%
    Motor Enhancement 12.0% 78%
    Tactile Intimacy Enhancement 12.0% 82%

    Adverse Effects 58

    Anxiety 36.4% 81%
    Visual Distortions 28.5% 83%
    Jaw Clenching 28.1% 84%
    Insomnia 24.0% 83%
    Dysphoria 22.0% 83%
    Confusion 20.3% 80%
    Nausea 19.8% 77%
    Body Load 16.0% 80%
    Thought Disorganization 14.0% 78%
    Muscle Tension 13.8% 70%
    Auditory Effects 12.5% 84%
    Body Temperature Change 12.0% 81%
    Dry Mouth 10.0% 83%
    Headache 8.3% 80%
    Paranoid Ideation 8.0% 78%
    Dizziness 8.0% 80%
    Tremor 8.0% 79%
    Heart Rate Increase 6.0% 90%
    Muscle Spasm 6.0% 87%
    Fear 6.0% 87%

    Combinations TripSit

    Cross-Check Methylone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Euphoric and Extremely Peaceful positive exp #46340

    This is a report of my first experience with methylone. I had already had numerous experiences with magic mushrooms, pot, and beer, but that was the extent of my drug experiences. I was on a trip with a tour guide and 3 other people. One of them knew the guide, and the other two were a recently married couple.

    open · 170 mg oral
    A Wonderful Evening With Beautiful People positive exp #99233

    Dose: 150mg First, as a little context, my own experience. Over the last year and a half, I've drunk my share of alcohol, inhaled a ton of nitrous, smoked a bit of cannabis, despite the fact that it's never interested me particularly, dosed on acid six or seven times, my favorite thus far, and tried MDMA once.

    anonymous · 150 mg oral / 80 mg oral / 120 mg oral
    Unbelievably, Unexpectedly, Beautiful positive exp #79767

    This was only my second experience with methylone, but it was so personally remarkable that I felt it worth documenting. My first experience had been with a single 200mg dose, oral, a week prior to this one, and had been thoroughly pleasant, but I felt it could have been improved.

    DocApos · 4 glasses oral / 200 mg oral / 150 mg oral
    The Head and the Heart neutral exp #105042

    Previous experience: Ketamine, Cocaine, Benzos, Opiates, Cannabis, MDMA, MDA, DMT, LSD, Psilocybin, Amphetamine salts, Methamphetamine Other participant: TS2 is male, approximately 300lbs, and also an experienced and educated drug user.

    Tryptofan · 130 mg oral / 1 hit smoked / 60 mg insufflated / 1 smoked
    The Feeling Within neutral exp #53665

    Mindset: Very good mood, prepared for the experience Method of dosing: Capsule Dosage: 175mgs Duration: 4-5 hours Medications: None It had been a long time since I had experimented with Methylone, and I was finally graciously given the chance to experience that wonderful beauty in everything again, little did I know, I...

    Sepulfreak · 175 mg oral / smoked / smoked
    A Seeker's Best Friend neutral exp #115572

    I am not an expert on the use of psychoactives. Iย’ve used LSD, psilocybic mushrooms, and Methyloneย’s cousins: MDA, MDMA a handful of times, but Iย’m no frequent flyer.

    Clear Fire · 200 mg oral
    I Didn't Want It To End cautionary exp #93379

    The only drug experience I've had were with cannabis and benzos. I used to smoke weed almost every night with my cousins, but I hated it. I always felt anxious, paranoid, and just terrible. I live with my boyfriend now, and he had recently experimented with MDMA and had a great time.

    karika
    A Valuable, Low Intensity Entheogen cautionary exp #85287

    I discovered this compound while reading a website and decided to give it a try, given its legal status in the USA. I order it online and am surprised when it arrives from China in just over a week. It is shipped discreetly. I plan on giving this a try by myself first to discover dosages and effects.

    Entheonaut · 100 mg oral / 33 mg oral / 45 mg oral / 45 mg oral
    Bluelight 8 threads 7 neutral 1 cautionary visit
    Methylone Experienced Getting To Know Her All Over Again neutral

    June 2002 190 mg methylone It was the first night of camping in our month long tour of the American Southwest. My partner and I were staying at the Homolovi Ruins, a sacred place to the Hopi located just outside of Winslow, Arizona.

    scraped 2026-03-14
    Methylone Experienced The Feeling Within neutral

    ''The Feeling Within'' Monday June 5th 2006 It had been a long time since I had experimented with Methylone, and I was finally graciously given the chance to experience that wonderful beauty in everything again; little did I know, I was about to have one the best experiences of my entire life.

    scraped 2026-03-14
    Methylone Exp The Collective Consciousness Experience neutral

    So I had a TRUE ++++ tonight from methylone. YES, methylone. None of this has any time stamps on it and it is quite long but trust me it is worth the read... Im still in awe of everything I saw and learned and experienced and felt...

    scraped 2026-03-14
    Methylone Retrospective Heart Chakra Express neutral

    Methylone. 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one. MDMCAT. have not written a trip report for awhile, but felt this substance deserves special mention, primarily for its psychotherapeutic value, which is substantial and differs from many other compounds i have sampled, said to be tools tailored for such...

    scraped 2026-03-14
    Methylone Inexp Light At The End Of The Tunnel neutral

    Okay so here's the deal. I've had stuff that was labelled as methylone before but it was nowhere near this potent and it didn't have this much power to it. Therefore, I'm questioning if what I had wasn't really MBDB or some other related substance instead. Here's the set.

    scraped 2026-03-14
    Methylone Methyl 1 Mdmcat First Time Afterglow Tranquillity neutral

    Methyl-1 (MDMCat) --- first time --- Afterglow Tranquillity Methylone (2-methylamino-1-[3,4-methylenedioxyphenyl]propan-1-one) Also known as Methylenedioxy-methcathinone (MDMCat). I call it Methyl-1 for short. Ate 100mg. It had a bitter chemical taste that reminded me a lot of the 2C-I I got from the same source.

    scraped 2026-03-14
    Methylone Semi Experienced Binging And Paying The Price neutral

    Ok, so I decided to try an give an account of what in retrospect I consider to be an extremely stupid and irresponsible indulgence in Methylone and 4-FA combined.... Within 3 days I went through roughly 2 grams of M1 and roughly 1 gram of 4-FA.

    scraped 2026-03-14
    Methylone Experienced Seizure And Near Death Experience cautionary

    Hey everyone, this is my first real attempt at writing one of these reports so be nice I would say that I am fairly experienced with mephedrone/methylone/butylone/mdma having used all of these on numerous occasions in the past (mdma being the compound of choice of course ), in the fortnight leading up to this event I k...

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    [MEGA] Cathinone Subthread - Methylone, ethylone, pentylone... Chemical alphabet soup

    Methylone This thread is mainly for Methylone, AKA BK-MDMA or 3,4-methylenedioxy-N-methylcathinone. It will also cover it's relative analogues, pentylone ethylone, butylone, and several others.

    Read full thread on Bluelight โ†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #110: MDMC

    “A flood of paresthesia at the 30 minute point, and then nothing. There was the development of a plus one-and-a half effect over the next hour with the tendency to drift into a dozing state with hypnogogic imagery. There were colored letters in the periphery of my visual field. There was no appetite loss nor was there any blood pressure rise. And no eye jiggle or teeth clenching. I was out of the experience in 4 to 5 hours. A repeat of this level a few days later gave a bare possible threshold with no other effects.”

    โ€” Alexander Shulgin, PiHKAL (with 150 mg)

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