Noopept
Aliases: gvs-111, omberacetam, sgs-111
Summary
Noopept is a synthetic peptide nootropic, significantly more potent by weight than piracetam. It functions as a prodrug of cycloprolylglycine and modulates AMPA receptors. Often used for cognitive enhancement with purported benefits for memory, focus, and neuroprotection.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5mg | 10mg | 10-20mg | 20mg+ |
| Sublingual | 2-5mg | 5-10mg | 10mg | 10mg+ |
| Insufflated | 2-5mg | 5-10mg | 10mg | 10mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-45 min | 1-3 hrs | 1-2 hrs | 2.8-6.2 hrs |
| Sublingual | 0-5 min | 10-20 min | 1-3 hrs | 1-2 hrs | 2.2-5.4 hrs |
| Insufflated | 0-5 min | - | 3-6 hrs | - | 3-6.1 hrs |
Tolerance
Tolerance Decay
Full tolerance
0h
Half tolerance
7d
Baseline
~14d
Many report subtle tolerance after continuous daily use for weeks; limited to anecdotal evidence. Spacing doses (e.g., 2–3 days/week) or cycling may help maintain effect. Cross-tolerance within racetams is plausible but not quantified.
Cross-Tolerances
Piracetam
20%
Aniracetam
20%
Effects
Aggregated from 13 Erowid experience reports
Positive Effects 7
Stimulation
53.8%
70%
Focus Enhancement
38.5%
70%
Empathy
30.8%
70%
Music Enhancement
23.1%
70%
Color Enhancement
23.1%
70%
Euphoria
23.1%
70%
Introspection
23.1%
70%
Adverse Effects 3
Anxiety
69.2%
70%
Confusion
23.1%
70%
Memory Suppression
23.1%
70%
Noopept's nerd page
Pharmacology, chemical data, effect profiles, and more
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