The reason I'm posting this for the purpose of hopefully helping others should they be in the same position I was in. It was about five years ago at my friend's proposal party, that I suffered a pretty severe concussion.
Noopept
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- toxicity data (PsychonautWiki)
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- toxicity data (PsychonautWiki)
- classified Research-chemical
Aliases: gvs-111, omberacetam, sgs-111
Summary
Noopept is a synthetic peptide nootropic, significantly more potent by weight than piracetam. It functions as a prodrug of cycloprolylglycine and modulates AMPA receptors. Often used for cognitive enhancement with purported benefits for memory, focus, and neuroprotection.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5mg | 10mg | 10-20mg | 20mg+ |
| Sublingual | 2-5mg | 5-10mg | 10mg+ | - |
| Insufflated | 2-5mg | 5-10mg | 10mg+ | - |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-45 min | 1-3 hrs | 1-2 hrs | 3-5 hrs |
| Sublingual | 0-5 min | 10-20 min | 1-3 hrs | 1-2 hrs | 3-6 hrs |
| Insufflated | 0-5 min | - | 3-6 hrs | - | 3-6 hrs |
Tolerance
Build-up
develops over several weeks of prolonged and repeated use
Reset
1 - 2 weeks
Tolerance Decay
Half tolerance
7d
Baseline
~14d
Many report subtle tolerance after continuous daily use for weeks; limited to anecdotal evidence. Spacing doses (e.g., 2–3 days/week) or cycling may help maintain effect. Cross-tolerance within racetams is plausible but not quantified.
Cross-Tolerances
Effects
Aggregated from 4 single-substance Erowid experience reports; 9 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 4 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 0
Adverse Effects 1
3 of 4
–
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Reddit 8 reports 5 neutral 3 cautionary visit
Its not a placebo. You are simply just unresponsive. I'd say noopept is on the same level as phenibut when it comes to raw effects. Here are some of my effects when it came to noopept when i was on it. 1. Motivation without trying or thinking.
Ok this might get taken down, I've tried posting on several places regarding noopept so lets hope this one works. And honestly your guys' specialty is noopept so should've went here first.
thought it was bunk. tried nasal, oral, sublingual for a month. mainly sublingual, doses of 5-30mg i didn’t notice much consciously. felt the exact same. my french improved drastically, and my verbal fluency as well, but i didn’t notice this until after i ran out.
A wild experience. I was recently told I should ask my doctor about ADHD. Supposedly, I have the symptoms and based on my ever increasing mental health problems, I probably have it.
Noopept, got a call from my local police station, lady explained that customs had confiscated my parcel containing prescription drug phentinol (painkiller) but since it was my first offence they were willing to have an informal chat and discuss possible community service! I said...
I bought a bottle of noopept capsules about 4 weeks ago. I had been using Mindlab pro capsules for about a week before the noopept came. Mindlab pro didn't seem to give me any visible effects, but when I took the mindlab pro capsules along with the noopept (2 mindlab pro capsules...
I’ll keep it short. Supplements are too good to be true. First day I took 150mg alpha gpc, second day 300mg alpha gpc with 150mg noopept. Third day, didn’t take any as I’m still feeling the effects and I don’t want to increase my tolerance.
Erowid 3 reports 1 positive 1 neutral 1 cautionary visit
I felt compelled to wright a report about my experience with this drug mainly due to my unexpected results as well as the fact that I have been able to find few to no reports on this Chemical. Background Drug Experience: I've used more than 30 hard drugs so its not worth me listing them all.
I have experimented with noopept in the past, but often neglected the importance of having a high-choline diet while using it. It still gave me effects, but now that I have been consuming more choline, the effects are much more pronounced. Some background about myself, including the "standard" list of drugs.
Background: 32 year old male PhD student. Into psychedelics & meditation. Why this drug: I read some trip reports about Noopept that really sparked my interest. Someone called it "a great alternative to LSD". Experiment: I took 20 mg every morning for two consecutive days.
Noopept's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has Noopept, but its built-in entry only covers Insufflated, Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "Noopept (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Custom Unit doses
- Sublingualcommon ~ 7.5 mg
Dose & duration (reference)
Noopept: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Sublingual dose (mg): light 2-5 · common 5-10 · strong 10+ Sublingual duration: onset 0-5m · come-up 10-20m · peak 1-3h · offset 1-2h · total 3-6h · after-effects 24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Noopept? Let us know. Reports are reviewed by moderators — this is not posted publicly.