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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Oxazepam Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 3 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 17 combo interactions documented
    • PubChem toxicity data

    Aliases: Serax, Sobril, Alepam, Serepax, Seresta

    Depressant Benzodiazepine

    Summary dose.wiki TripSit

    Oxazepam is an intermediate-acting benzodiazepine with slow onset used for anxiety, alcohol withdrawal, and insomnia. It is the active metabolite of diazepam, prazepam, and temazepam. Oxazepam has a slower onset than most benzodiazepines and is considered less sedating than alprazolam or lorazepam at therapeutic doses.

    Dose Information dose.wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-30mg 30-45mg 45mg+
    Light Common Strong Heavy

    Benzo Equivalence Calculator

    mg
    20.0 mg Oxazepam
    =
    — mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 0.5-2 hrs 30-60 min 2-4 hrs 4-8 hrs 1-3 hrs 7-8 hrs

    Effect Profile

    5 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.3
    Strong+ 7/10

    Strong anxiolysis and cognitive impairment with moderate sedation and euphoria

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant
    Sedation / Relaxation ×2
    7
    sedation drowsiness muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    9
    motor control loss cognitive impairment memory suppression double vision
    Euphoria / Mood Lift ×1
    6
    physical euphoria disinhibition
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Oxazepam
    View methodology →

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Oxazepam, but its built-in data can be thinner than ours. Importing this file adds a separate "Oxazepam (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "Oxazepam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended

    Tolerance Decay

    Full tolerance 14d Half tolerance 14d Baseline ~60d

    Dependence and tolerance can emerge within weeks with daily or near‑daily use; cross‑tolerance extends across GABA-A positive allosteric modulators. Data are mixed and largely based on class-level evidence and clinical practice rather than oxazepam-specific prospective trials.

    Cross-Tolerances

    Other benzodiazepines
    100%
    Z-drugs
    70%
    Alcohol (GABAergic)
    50%
    Barbiturates
    70%

    Effects Erowid

    Aggregated from 5 Erowid experience reports

    Positive Effects 1

    Anxiety Suppression 80.0% 70%

    Adverse Effects 0

    Combinations

    Cross-Check Oxazepam with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 1 report 1 neutral visit
    No Permanent Fix--Except for Muscle Tension neutral exp #114783

    Used as prescribed for muscle tension I had been bothered with for years. Dissolved and I felt more centered, clear, and slightly sluggish while using. It's great for flights, and for sleeping on friends' couches and other less physically comfortable situations.

    supermegafon · 75 - 100 mg oral

    Pill Identifiers

    6 known pill identifiers on record — view imprints, colors, shapes, and images
    →
    Oxazepam's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki