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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Alprazolam

    Aliases: Bars, Xans, Xanax, Tafil, Kalma, prazolam, ksalol, niravam

    Categories

    Depressant Benzodiazepine
    Alprazolam structure

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Alprazolam is a prescription triazolobenzodiazepine primarily used for panic disorder and generalized anxiety disorder. It should only be used under medical supervision due to high abuse potential and severe withdrawal syndrome. Never discontinue abruptly after regular use—always taper gradually under medical guidance to prevent potentially fatal seizures. Higher doses significantly increase blackout risk and compulsive redosing. Alprazolam is metabolized by CYP3A4; inhibitors significantly increase blood levels and side effects.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 0.25-0.5mg 0.5-1.5mg 1.5-2mg 2mg+
    Inhaled 0.05-0.25mg 0.25-0.5mg 0.5-1mg 1mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 12-30 min 48-90 min 1-2 hrs 2-4 hrs 6-24 hrs 300-0 min
    Inhaled 0 min 6-12 min 1-2 hrs 2-3 hrs 360-0 min 300-0 min

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended
    Cross-tolerance
    Diazepam Clonazepam Lorazepam Etizolam Bromazolam Clonazolam Flualprazolam Flubromazolam

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Muscle relaxation
    • Anxiolytic
    • Muscle Relaxant
    • Seizure suppression
    Negative
    • Loss of motor skills
    • Respiratory depression
    • Dry mouth
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hiccups
    • Sleepiness
    Positive
    • Anxiety suppression
    • Euphoria
    • Dream potentiation
    Negative
    • Motor control loss
    • Amnesia
    • Cognitive impairment
    • Delusions of sobriety
    • Emotion suppression
    • Analysis suppression
    • Compulsive redosing
    • Dream suppression
    • Loss of time
    • Delusions
    • Dizziness
    • Information processing suppression
    • Thought deceleration
    • Delusion
    • Anxiety
    • Irritability
    • Thought disorganization
    • Memory suppression
    • Confusion
    • Language depression
    • Motivation depression
    Positive
    Negative
    • Disinhibition
    • Visual acuity suppression
    • Decreased Libido
    • Acuity Suppression
    • Appetite suppression
    Neutral
    • Perception of bodily heaviness
    • Appetite intensification
    • Dulled perception
    • Appetite fluctuation
    • Hallucinations

    Combinations TripSit

    Helpful Links

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