5-APB - Substance Search

Summary dose.wiki Erowid TripSit PsychonautWiki

5-(2-Aminopropyl)benzofuran (commonly known as 5-APB) is a lesser-known novel entactogen of the benzofuran class that produces MDA-like entactogenic and stimulating effects when administered. It is structurally related to entactogens like 5-MAPB, 6-APB, and MDA. 5-APB was first synthesized in 1993 by psychedelic chemist and researcher David E.

Dose Information dose.wiki TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	40-60mg	60-80mg	80-100mg	100mg+

Light Common Strong Heavy

Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	19-60 min	45-90 min	2-4 hrs	1.5-3 hrs	6-48 hrs	7-8 hrs
Insufflated	4-15 min	19-40 min	2-4 hrs	1.5-3 hrs	4-24 hrs	7-8 hrs
Rectal	10-30 min	45-90 min	2.5-4 hrs	2-3 hrs	6-24 hrs	7-8 hrs

Effect Profile

16 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 5.5

Strong 6/10

Strong body load, visuals, and auditory effects with mild headspace

Visual Intensity ×3

8

visual geometry color enhancement tracers pattern recognition enhancement

Headspace Depth ×3

4

personal meaning enhancement emotion enhancement time distortion

Auditory Effects ×1

8

auditory distortion auditory hallucination

⚠ Body Load / Somatic Effects ×1

10

nausea temperature regulation suppression vasoconstriction teeth grinding increased heart rate jaw clenching +1 more

Empathogen 9.1

Intense+ 9/10

Strong empathy and euphoria with moderate stimulation and sensory enhancement

Empathy / Social Openness ×3

10

empathy enhancement empathy empathy, affection and sociability enhancement feelings of empathy sociability enhancement affection enhancement +1 more

Euphoria / Mood Elevation ×2

10

physical euphoria euphoria cognitive euphoria emotion enhancement

Stimulation ×1

7

stimulation wakefulness teeth grinding increased heart rate

Sensory Enhancement ×1

7

tactile enhancement color enhancement increased libido

Stimulant 6.9

Strong+ 7/10

Strong euphoria, focus, and anxiety/jitters with mild stimulation

Stimulation / Energy ×3

5

stimulation wakefulness

Euphoria / Mood Lift ×2

10

physical euphoria euphoria cognitive euphoria motivation enhancement

Focus / Productivity ×2

10

focus enhancement analysis enhancement memory enhancement motivation enhancement thought acceleration

⚠ Anxiety / Jitters ×1

10

anxiety paranoia increased heart rate teeth grinding jaw clenching vasoconstriction +1 more

Based on reports from:

Erowid Experience Reports PsychonautWiki 5-APB

Add missing routes to PsychonautWiki Journal

The PsychonautWiki Journal app already has 5-APB, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

⬇ Download import file Import this file as custom substances and you get "5-APB (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Dose & duration (reference)

5-APB: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)

Insufflated dose (mg): threshold 10
Rectal dose (mg): threshold 15-25

Insufflated duration: onset 4-15m · come-up 19-40m · peak 2-4h · offset 1.5-3h · total 7-8h · after-effects 4-24h
Rectal duration: onset 10-30m · come-up 0.75-1.5h · peak 2.5-4h · offset 2-3h · total 7-8h · after-effects 6-24h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 1d Half tolerance 7d Baseline ~14d

Pattern inferred from user reports across benzofurans and MDMA-like agents. Acute tolerance develops within a session; effects are notably blunted by redosing late. Subjective tolerance partially subsides over 1–2 weeks, with baseline often reported after 3–5 weeks. Data quality: anecdotal/community-derived.

Cross-Tolerances

MDMA

60%

MDA

60%

6-APB

70%

5-MAPB

70%

Effects Erowid Bluelight

Aggregated from 10 Erowid and 6 Bluelight experience reports

Positive Effects 16

Euphoria 93.7% 91%

Music Enhancement 75.0% 89%

Body High 50.0% 89%

Tactile Enhancement 50.0% 90%

Closed-Eye Visuals 33.3% 85%

Contentment 33.3% 80%

Sociability Enhancement 33.3% 75%

Focus Enhancement 33.3% 75%

Empathy 31.3% 85%

Visual Distortions 31.2% 75%

Numbness 16.7% 80%

Enhanced Colors 16.7% 80%

Taste Distortion 16.7% 85%

Love 16.7% 80%

Empathogenic Connection 16.7% 85%

Tingling 16.7% 80%

Adverse Effects 9

Anxiety 40.0% 70%

Body Load 33.3% 82%

Nausea 33.3% 82%

Jaw Clenching 31.3% 75%

Confusion 30.0% 70%

Diarrhea 16.7% 70%

Emotional Blunting 16.7% 75%

Sociability Suppression 16.7% 80%

Irritability 16.7% 65%

Combinations TripSit

Cross-Check 5-APB with another substance

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Bluelight 2 threads 2 neutral visit

5 Apb 80 Mg Pill Head Perspective Not What I Was Looking For neutral

This is my first report on bluelight so here goes! For a quick background on me to get where this report is coming from I have been an on off heavy user of mdma + cathonines for a few years.

5 Apb 110mg First Time Amazing Body High neutral

Forewarning: As with my 6-APB report, I'd like to add a word of caution to this. 5-APB is an MDA analogue, and as such it should be treated with the same caution as MDA - using it more than once a month (ideally you should use it less frequently than once a month too) is likely to lead to similar issues of serotonin re...

5-APB's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

📘 Experience Reports 📖 dose.wiki 📖 TripSit 📖 PsychonautWiki

Report an issue or suggest an edit

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5-APB Well-documented Well-documented Multiple authoritative sources agree on dosing and effects. 7 corroborating sources 1 ROA with full dose ladder duration data present 20 combo interactions documented toxicity data (PsychonautWiki) classified Research-chemical