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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2-FMA

    Aliases: 2-fluoro-methamphetamine, 2fma

    Stimulant Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    2-Fluoromethamphetamine (also known as 2-FMA) is a novel stimulant substance of the amphetamine class. It is a structural analog of methamphetamine and is related to 2-FA, 3-FA, and 4-FMA. 2-FMA produces its stimulant effects through action at dopamine and norepinephrine receptors in the brain.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 5-15mg 15-30mg 30-50mg 50mg+
    Insufflated 5-15mg 15-30mg 30-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 15-40 min 2.5-4 hrs 2-3 hrs 4-12 hrs 5.2-8.7 hrs
    Insufflated 20-40 min 10-20 min 1-3 hrs 1.5-3 hrs 2-4 hrs 3-7 hrs
    Rectal 15-30 min 20-30 min 2-3 hrs 2-3 hrs 4-12 hrs 4.6-7 hrs
    Intravenous 0-1 min 1-5 min 1.5-3 hrs 1.5-2 hrs 4-12 hrs 3-5.1 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.6
    Strong+ 7/10

    Strong euphoria, anxiety/jitters, and focus with mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding bruxism vasoconstriction +1 more
    Based on reports from:
    Effect Index Productive Stimulation without Euphoria Erowid Experience Reports PsychonautWiki 2-FMA
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Cross-Tolerances

    Stimulants
    Amphetamine
    75%
    Methamphetamine
    75%
    Lisdexamfetamine
    75%
    2-FA
    75%
    3-FA
    75%
    4-FMA
    75%
    Methylphenidate
    75%
    Empathogens
    4-FA
    40%

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Increased energy/alertness
    • Physical euphoria
    • Bronchodilation
    Negative
    • Dry mouth
    • Increased perspiration
    • Pupil dilation
    • Increased heart rate
    • Increased blood pressure
    • Vasoconstriction
    • Teeth grinding
    • Weight loss
    • Sweating
    • Bruxism
    • Nausea
    • Headache
    • Temporary erectile dysfunction
    • Abnormal heartbeat
    Neutral
    • Restless legs
    • Decreased need for sleep
    • Decreased appetite
    • Disturbed sleep patterns
    • Itchiness
    • Frequent urination
    • Increased bodily temperature
    • Brightness alteration
    • Stamina intensification
    Positive
    • Focus enhancement
    • Motivation enhancement
    • Analysis enhancement
    • Wakefulness
    • Cognitive euphoria
    • Euphoria
    • Increased sociability
    • Mood lift
    • Anxiety suppression
    Negative
    • Anxiety
    • Compulsive redosing
    • Aggressiveness
    • Cognitive fatigue
    • Depression
    • Irritability
    • Thought deceleration
    • Emotion suppression
    • Delusion
    • Paranoia
    • Memory suppression
    • Depersonalization
    • Psychosis
    • Motivation depression
    Neutral
    • Thought organization
    • Time distortion
    • Excessive talking
    • Moodiness
    • Thought acceleration
    • Ego inflation
    • Focus intensification
    Positive
    • Bodily control enhancement
    • Increased libido
    • Tactile enhancement
    • Increased music appreciation
    Negative
    • Appetite suppression
    • Dehydration
    • Disinhibition
    Neutral
    • Increased sexuality
    • Visual and auditory hallucinations
    • Drifting
    • Tactile intensification

    Combinations TripSit

    Trip Reports Effect Index

    Productive Stimulation without Euphoria froggie
    2-FMA's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki 📖 TripSit