Home
    Disclaimer
    Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Hydrocodone Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data

    Aliases: Vike, Vics, Norco, Hydro, Lortab, vicodin

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Hydrocodone is most commonly prescribed in combination with acetaminophen (Vicodin, Norco, Lortab). When used recreationally or in high doses, the acetaminophen component poses serious risk of liver damage or failure. Respiratory depression is the primary cause of fatal overdose, particularly when combined with other CNS depressants.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-25mg 25-40mg 40mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-30 min 30-60 min 1-2 hrs 2-4 hrs 12 hrs 4-8 hrs

    Opioid MME Calculator

    ⚠ Citation & Disclaimer: Conversion factors sourced from the NIH HEAL Initiative MME Calculator (Adams et al., PAIN 2025), the CDC 2022 Clinical Practice Guideline for Prescribing Opioids for Pain, and the MDCalc MME Calculator. These are approximate equianalgesic ratios for educational reference only. Individual responses vary significantly based on genetics, tolerance, cross-tolerance, and route of administration. This is not medical advice. Do not use these conversions to adjust opioid dosing without professional medical guidance.
    mg
    10 mg Hydrocodone
    mg Morphine

    ⚠ Equianalgesic dose ratios are approximations and do not account for genetic factors, tolerance, incomplete cross-tolerance, or pharmacokinetic variations. Methadone conversion is especially variable at higher doses. Always consult a healthcare provider before making any changes to opioid therapy.

    Effect Profile

    307 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 266 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 8.0
    Intense 8/10

    Strong euphoria, itching/nausea, pain relief, and sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria mood lift
    Analgesia ×2
    9
    pain relief analgesia
    Sedation / Relaxation ×1
    8
    sedation dream potentiation
    Itching / Nausea ×1
    10
    nausea constipation dry mouth

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Tolerance builds with repeated dosing over days to weeks and decays over 1–3+ weeks of abstinence; loss of tolerance markedly increases overdose risk after a break. Cross‑tolerance exists across mu‑opioid agonists.

    Effects Erowid Bluelight

    Aggregated from 266 Erowid and 41 Bluelight experience reports

    Positive Effects 43

    Euphoria 47.2% 89%
    Contentment 41.5% 84%
    Sedation 35.2% 86%
    Anxiety Suppression 27.7% 82%
    Stimulation 25.9% 70%
    Sociability Enhancement 24.4% 84%
    Thought Deceleration 22.0% 78%
    Music Enhancement 21.2% 85%
    Empathy 21.2% 80%
    Hot Flashes 19.5% 82%
    Drowsiness 19.5% 90%
    Tingling 17.1% 85%
    Body High 16.0% 88%
    Vivid Dreams 14.6% 82%
    Tactile Enhancement 13.1% 85%
    Focus Enhancement 12.4% 80%
    Color Enhancement 10.5% 70%
    Numbness 9.8% 85%
    Heaviness 9.8% 81%
    Lightness 7.3% 77%

    Adverse Effects 32

    Nausea 29.0% 83%
    Dizziness 22.0% 84%
    Vomiting 19.5% 90%
    Itching 19.5% 84%
    Confusion 12.7% 85%
    Stomach Cramps 12.2% 77%
    Headache 11.4% 75%
    Thought Disorganization 9.8% 76%
    Blurred Vision 7.3% 83%
    Irritability 7.3% 73%
    Sweating 5.6% 80%
    Memory Suppression 5.2% 75%
    Amnesia 4.9% 95%
    Muscle Tension 3.4% 70%
    Increased Heart Rate 3.0% 70%
    Seizure 2.6% 70%
    Lightheadedness 2.4% 80%
    Panic 2.4% 80%
    Dysphoria 2.4% 85%
    Sadness 2.4% 90%

    Combinations TripSit

    Cross-Check Hydrocodone with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Warmth Bliss Glow positive exp #93090

    There is nothing sweeter than the incredible glow and high of opiates. I have experimented with a few different drugs. Salvia Divinorum is my second favorite, but solely due to the enlightenment properties and nothing else. Alcohol has negative side-effects; I'm a light-weight and don't eat too much...

    Enthusiast · 7.5 mg oral / 750 mg oral
    Coming Down Is the Hardest Thing positive exp #86470

    It’s hard to say when I began using opiates. All I know is that a few years back, when I was maybe 15-ish, I was in high school, living with my dad, and I realized that certain prescription pills would get me high. I found some hydrocodone (vicodin) in my stepmom’s drawer and took a couple. Then we went shopping.

    chicacodone · repeated
    Stronger, Wiser, and A Little Colder positive exp #27114

    I hope and wish that everyone reading this take this seriously. First I will give a short background of my self. I am 18 years old, male, and started off just smoking pot, mixing that with a few beers and shots. It was about a year ago that a friend offered me vicodin.

    SCIPHAN123 · repeated oral / repeated oral / repeated smoked
    Worthy Solitary Experience neutral exp #8072

    My mother had had back surgery over a year ago, for which she was prescribed a bottle of 60 hydrocodone tablets. I watched the bottle carefully every time I visited, and noticed that it seemed to remain steadily at the same level.

    Jesse · oral
    A Mildly Euphoric Bliss neutral exp #68881

    I'll start by saying that I'm a pretty experienced drug user. I've experimented with MDMA (ecstasy), MDA (similar to MDMA), cocaine, alcohol, morphine, 2c-i, 2c-b, psilocybin mushrooms, LSD (acid), marijuana (daily), Cyclobenzaprine (muscle/skeletal relaxant), Ambien (sleep medication), and amphetamine.

    wonka88 · 20 mg oral / 2 g oral / 10 mg oral
    A First Timer's Low Dose neutral exp #80481

    Introduction: (Please excuse the extended introduction. This is my first report and I feel as though it is necessary.) I will start with some background information. I am 16 years old and, prior to this experience, I had never taken any drug recreationally.

    Michael · 10 mg oral / 1000 mg oral
    Nightmare? cautionary exp #13202

    Some background: I've done my share of drugs, but tend to stay away from pharmaceuticals, simply because I can usually find better drugs. However, I just had my wisdom teeth out a few days ago, and was looking for something to stop the pain I was experiencing and help me sleep, because I'd already finished off my 'scri...

    ms. vinegar · Hydrocodone (with Acetaminophen) · 10 mg oral / oral
    Norco Withdrawal Worse Than Expected cautionary exp #70150

    I’m older than a lot of the readers here and you would think that I would know better, but yes, I admit now that I am addicted to Hydrocodone. I’ve had a long and semi-successful life of drug use over the years.

    ExPothead · 60 mg oral
    Bluelight 7 threads 6 neutral 1 cautionary visit
    Hydrocodone 2nd Time 5 7 5 Vics neutral

    5 7.5 Vics I don't know if this counts as a true "trip." I always thought a trip can only be brought upon by my Acid and such. Well, it was my second time on Vicodien and my most enjoyable high. I popped 3 pills at lunch time. I didn’t feel much until I got to my 5th period class.

    scraped 2026-03-14
    Hydrocodone 15 Mg neutral

    well this was my third time using this. first time was like a month ago with 15mg and it was alright. made me really sleepy and relaxed, didnt get all the hype. next was last week where i only took 7.5mg. it was a little more euphoric and more talkative.

    scraped 2026-03-14
    Hydrocodone 85mg Potentiation Experienced Hydro neutral

    Tonight’s drug totals: 85 mg Hydrocodone 1 mg Alprazolam 50 mg diphenhydramine HCL Large bowl of top grade medical Marijuana 12.5 mg Zolpidem (separate) So tonight will be a large combination of my beloved Marijuana and Hydrocodone, mostly Hydrocodone .

    scraped 2026-03-14
    Hydrocodone 30mg Cwe Semi Experienced neutral

    so i had a large stash of painkillers consisting of hydros,oxys,and tylonol 4's. i went trough and distributed most of these during grad nite. in which graduating seniors get taken to a yaht club for an alcohol and drug free and safe night haha right. i smuggled them in and did not incriminate myself .

    scraped 2026-03-14
    Hydrocodone Semi Exp Everything And Nothing neutral

    I just finished typing this in the Erowid submissions box, just proofreading mostly and having a backup here Sorry it's so long. Substances taken earlier: One-a-day multivitamin and Magnesium supplement Drug experience: Marijuana, alcohol, tobacco, hydrocodone, amphetamines and methamphetamines, cocaine, various pills...

    scraped 2026-03-14
    Hydrocodone 35mg Very Experienced Or So I Thought neutral

    First my drug history. I started taking hydrocodone recreationally when i was 16. At my peak (appx. age 20) i was taking 90-150mg hyrocodone a day and 40-50mg percocet a day or if i was lucky a couple 20mg oxycontin a day. As of 2011 i was drug free for a year excluding alcohol.

    scraped 2026-03-14
    My Vicodin Experience 3x 5mg Hydrocodone cautionary

    Gender: Male Weight: 145lbs Age: 20 hey there, i just want to start off by saying i used to be addicted to vicodin in the past as a substitute for my addiction to harder drugs.

    scraped 2026-03-14

    Pill Identifiers

    Helpful Links