Summary
1D-LSD is a prodrug of LSD with a 1,2-dimethylcyclobutane-1-carbonyl group at the N1 position. User reports suggest it is approximately 15-25% less potent by weight than LSD-25, though this varies between individuals and batches. Some blotters sold as 1D-LSD have been found to contain 1T-LSD (1-thienoyl-LSD) instead; reagent tests confirm lysergamide presence but cannot distinguish between analogues. Users report a slightly faster onset (20-30 minutes) and somewhat shorter duration compared to LSD-25. Volumetric dosing is recommended for microdosing.
Perspectives
“This is by far the most potent 1-substituted LSD analogue I have tried. All the hallmarks of a lysergamide—patterned visuals, characteristic color schemes, extended duration with euphoric afterglow, and an analytical, sentimental, and joyous headspace.”
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 2-5 hrs | 2-4 hrs | 2-8 hrs |
| Sublingual | 20-40 min | 30-60 min | 2-5 hrs | 2-4 hrs | 2-8 hrs |
Tolerance
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Nausea
- Insomnia
- Vasoconstriction
- Pupil dilation
- Dilated pupils
- Sedation
- Decreased appetite
- Thought connectivity
- Conceptual thinking
- Euphoria
- Empathy enhancement
- Unity and interconnectedness
- Wakefulness
- Cognitive euphoria
- Anxiety
- Time distortion
- Ego dissolution
- Color enhancement
- Pattern recognition enhancement
- Visual geometry
- Tracers
- Increased music appreciation
- Tactile enhancement
- Light sensitivity
- Appetite suppression
- Dehydration
- Dulled perception