1D-LSD
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Syn-l-229
Summary
1D-LSD is a prodrug of LSD with a 1,2-dimethylcyclobutane-1-carbonyl group at the N1 position. User reports suggest it is approximately 15-25% less potent by weight than LSD-25, though this varies between individuals and batches. Some blotters sold as 1D-LSD have been found to contain 1T-LSD (1-thienoyl-LSD) instead; reagent tests confirm lysergamide presence but cannot distinguish between analogues.
Perspectives
“This is by far the most potent 1-substituted LSD analogue I have tried. All the hallmarks of a lysergamide—patterned visuals, characteristic color schemes, extended duration with euphoric afterglow, and an analytical, sentimental, and joyous headspace.”
Dose Information
No curated dose ladder is available for this substance. The figures below are drawn from SubstanceIndex (DoseWiki) as a fallback — often a conservative threshold only. Treat them as approximate and cross-reference before use.
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-75µg | 75-150µg | 150µg | 150µg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 30-60 min | 4-6 hrs | 10-14 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals with moderate body load, mild headspace
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 4 Erowid experience reports
Positive Effects 2
Adverse Effects 1
Combinations
Cross-Check 1D-LSD with another substanceHelpful Links
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