1D-LSD
Aliases: Syn-l-229
Summary
1D-LSD is a prodrug of LSD with a 1,2-dimethylcyclobutane-1-carbonyl group at the N1 position. User reports suggest it is approximately 15-25% less potent by weight than LSD-25, though this varies between individuals and batches. Some blotters sold as 1D-LSD have been found to contain 1T-LSD (1-thienoyl-LSD) instead; reagent tests confirm lysergamide presence but cannot distinguish between analogues.
Perspectives
“This is by far the most potent 1-substituted LSD analogue I have tried. All the hallmarks of a lysergamide—patterned visuals, characteristic color schemes, extended duration with euphoric afterglow, and an analytical, sentimental, and joyous headspace.”
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 2-5 hrs | 2-4 hrs |
| Sublingual | 20-40 min | 30-60 min | 2-5 hrs | 2-4 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals with moderate body load, mild headspace
Tolerance
Tolerance Decay
Effects
Aggregated from 4 Erowid experience reports