25B-NBOMe - Substance Search

Summary PsychonautWiki

25B-NBOMe (also known as Cimbi-36, NBOMe-2C-B and 2C-B-NBOMe) is novel psychedelic substance of the phenethylamine class. It is a member of the 25x-NBOMe series, a recently discovered group of potent psychedelic compounds derived from the 2C-x family. The name 25B-NBOMe, which is short-hand for 2C-B-NBOMe, indicates it is a derivative of the phenethylamine psychedelic 2C-B.

Dose Information TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Insufflated	50-200µg	200-350µg	350-500µg	500µg+
Sublingual	100-300µg	300-500µg	500-700µg	700ug+

Light Common Strong Heavy

Onset, Duration & After-effects TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Insufflated	1-4 min	-	8-12 hrs	-	2-6 hrs	8-12 hrs
Sublingual	18-42 min	30-90 min	4-6 hrs	2-4 hrs	2-6 hrs	8-12 hrs

Effect Profile

40 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Validated against 33 Erowid trip reports
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 8.8

Intense+ 9/10

Strong visuals, headspace, auditory effects, and body load

Visual Intensity ×3

10

internal hallucinations autonomous entities colour enhancement drifting tracers colour shifting +6 more

Headspace Depth ×3

10

conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression confusion +1 more

Auditory Effects ×1

10

auditory distortion auditory enhancement auditory hallucinations auditory hallucination

⚠ Body Load / Somatic Effects ×1

10

nausea vasoconstriction muscle tension increased heart rate

Based on reports from:

Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 25B-NBOMe

Tolerance

Build-up develops rapidly after a single use; redosing is especially dangerous

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 1h Half tolerance 10d Baseline ~14d

Cross-Tolerances

Lysergamides

LSD

60%

Tryptamines

Psilocybin

65%

Psilocin

65%

DMT

65%

5-MeO-DMT

65%

Phenethylamines

Mescaline

85%

2C-B

85%

2C-E

85%

Effects Erowid Bluelight

Aggregated from 33 Erowid and 7 Bluelight experience reports

Positive Effects 30

Color Enhancement 55.0% 85%

Stimulation 47.5% 80%

Music Enhancement 47.5% 90%

Entity Imagery 42.9% 77%

Joy 42.9% 83%

Euphoria 42.5% 90%

Tactile Enhancement 39.4% 70%

Empathy 32.5% 75%

Focus Enhancement 32.5% 70%

Introspection 30.0% 80%

Geometric Imagery 28.6% 85%

Pattern Recognition Enhancement 28.6% 75%

Open-Eye Visuals 28.6% 85%

Visual Trails 14.3% 70%

Gratitude 14.3% 85%

Contentment 14.3% 80%

Drowsiness 14.3% 80%

Insight 14.3% 80%

Sociability Enhancement 14.3% 75%

Brightness Enhancement 14.3% 80%

Adverse Effects 31

Visual Distortions 80.0% 82%

Anxiety 62.5% 88%

Confusion 45.0% 85%

Nausea 30.3% 70%

Muscle Tension 30.0% 75%

Dizziness 28.6% 85%

Panic 28.6% 88%

Fear 28.6% 90%

Body Temperature Change 28.6% 78%

Auditory Effects 27.5% 80%

Sedation 27.5% 85%

Thought Loops 25.0% 88%

Stomach Cramps 14.3% 75%

Pressure 14.3% 80%

Morphing 14.3% 85%

Motor Suppression 14.3% 75%

Field Narrowing 14.3% 75%

Auditory Delay 14.3% 70%

Body Distortion 14.3% 80%

Communication Suppression 14.3% 80%

Combinations TripSit

25B-NBOMe's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

📘 Experience Reports 📖 TripSit 📖 PsychonautWiki 📖 Bluelight