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    Disclaimer
    โ˜  NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25B-NBOMe Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: 25b

    Summary PsychonautWiki

    25B-NBOMe (also known as Cimbi-36, NBOMe-2C-B and 2C-B-NBOMe) is novel psychedelic substance of the phenethylamine class. It is a member of the 25x-NBOMe series, a recently discovered group of potent psychedelic compounds derived from the 2C-x family. The name 25B-NBOMe, which is short-hand for 2C-B-NBOMe, indicates it is a derivative of the phenethylamine psychedelic 2C-B.

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Insufflated 50-200ยตg 200-350ยตg 350-500ยตg 500ยตg+
    Sublingual 100-300ยตg 300-500ยตg 500-700ยตg 700ug+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Insufflated 1-4 min - 8-12 hrs - 2-6 hrs 8-12 hrs
    Sublingual 18-42 min 30-90 min 4-6 hrs 2-4 hrs 2-6 hrs 8-12 hrs

    Effect Profile

    40 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 33 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations autonomous entities colour enhancement drifting tracers colour shifting +6 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression confusion +1 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination
    Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction muscle tension increased heart rate

    Tolerance

    Build-up develops rapidly after a single use; redosing is especially dangerous
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    60%
    Tryptamines
    Psilocin
    65%
    DMT
    65%
    5-MeO-DMT
    65%
    Phenethylamines
    Mescaline
    85%
    2C-B
    85%
    2C-E
    85%

    Effects Erowid Bluelight

    Aggregated from 33 Erowid and 7 Bluelight experience reports

    Positive Effects 30

    Color Enhancement 55.0% 85%
    Stimulation 47.5% 80%
    Music Enhancement 47.5% 90%
    Entity Imagery 42.9% 77%
    Joy 42.9% 83%
    Euphoria 42.5% 90%
    Tactile Enhancement 39.4% 70%
    Empathy 32.5% 75%
    Focus Enhancement 32.5% 70%
    Introspection 30.0% 80%
    Geometric Imagery 28.6% 85%
    Pattern Recognition Enhancement 28.6% 75%
    Open-Eye Visuals 28.6% 85%
    Visual Trails 14.3% 70%
    Gratitude 14.3% 85%
    Contentment 14.3% 80%
    Drowsiness 14.3% 80%
    Insight 14.3% 80%
    Sociability Enhancement 14.3% 75%
    Brightness Enhancement 14.3% 80%

    Adverse Effects 31

    Visual Distortions 80.0% 82%
    Anxiety 62.5% 88%
    Confusion 45.0% 85%
    Nausea 30.3% 70%
    Muscle Tension 30.0% 75%
    Dizziness 28.6% 85%
    Panic 28.6% 88%
    Fear 28.6% 90%
    Body Temperature Change 28.6% 78%
    Auditory Effects 27.5% 80%
    Sedation 27.5% 85%
    Thought Loops 25.0% 88%
    Stomach Cramps 14.3% 75%
    Pressure 14.3% 80%
    Morphing 14.3% 85%
    Motor Suppression 14.3% 75%
    Field Narrowing 14.3% 75%
    Auditory Delay 14.3% 70%
    Body Distortion 14.3% 80%
    Communication Suppression 14.3% 80%

    Combinations TripSit

    Cross-Check 25B-NBOMe with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 2 positive 4 neutral 2 cautionary visit
    Psychedelic Bubbles positive exp #98812

    Prequel: I wanted to specifically enter this story, as it is the most recent enjoyable trip I have had with the nBomes and since that there is barely anything on 25B, which I have nicknamed her Beautrice-25 for her incredible beauty, the gemstone of all nBomes that are more of a true psychedelic than just a common good...

    Ramnement · 600 ug sublingual
    Strong Euphoria Love and Smiles positive exp #97629

    I've tried 25i-NBOMe and 25c-NBOMe prior to this. I knew 25b would be amazing as well. The setting was in my room with easy access to music, drawing, and my computer. It was mainly a test to experiment this compound before doing it at another setting.

    25Bliss · 0.5 hits buccal / inhaled / smoked
    Another NBOMe Tragedy. Two Tabs of 25B-NBOMe Killed My Brother. neutral exp #103021

    [Erowid Note: A first hand report of an experience and report of a fatality. From Reddit/r/Drugs . Reposted with permission. We have not yet received independent confirmation of this fatality, but believe it is factual.] This past Friday, I came home from classes around 2:30 PM and found my younger, 18-year-old brother...

    PainfulRegret · 2 hits buccal / smoked / smoked
    Euphoria and Paranoia Intertwined neutral exp #102233

    Throughout the past 2 years, I've been a semi-regular user of numerous substances, to keep the list short I'll only mention the ones I've done more than 15-20 times, they include Ketamine, LSD, 4-MEC, 4-FA , shrooms, MDMA, cannabis of course, and a few other 'designer' amphetamines, so I'm not an expert by any means on...

    vi11a · smoked / 1 tablet oral
    First Time Trip on 25B NBOMe neutral exp #99650

    To start, a bit about myself. I live in the UK, and got hold of some NBOMe series chemicals from what appeared to be a reputable website after having an interest in taking hallucinogens for a few years and doing a lot of research. In the end I ended up buying on a whim and, frankly, I wish I'd tried them earlier.

    OeasterPoeastman · 75 mg oral / repeated smoked / 1 hit sublingual
    Oh Beautiful Bromine neutral exp #98515

    Set: Just woke up from 6 hours of sleep. Setting: Friday Afternoon, around my college town. Previous Experiences: Cannabis, 6-APB, MDMA, 4-AcO-DMT, 2C-E, 2C-T-2, 25C-NBOMe, 25I-NBOMe, Mushrooms, DMT, Amphetamine, 2C-I, 5-MeO-MiPT.

    MrMoran · 500 ug buccal / repeated smoked
    Tears for the Lost Souls cautionary exp #100475

    Background: For longer than I can remember I was on anti-depressants and high blood pressure medication. The combination literally drove me crazy. My speech became broken and fragmented and my life was dominated by lustful impassivity.

    Casandra · 330 ug insufflated
    Proceed With Caution cautionary exp #99147

    Desired effects: To go deeper than ever before Intensity: Overwhelming Source: RC vendor Iย’ve been experimenting with the NBOMe class of phenethylamines the past few months, mostly with 25C-NBOMe but also with 25I and 25B laid out as bottlers.

    Antibody2 · 1 hit vaporized / 200 mg oral / 1 cig. smoked / 200 mg oral
    Bluelight 2 threads 1 positive 1 neutral visit
    25b Nbome 1mg First Time Quite Enjoyable positive

    I have a few mgs of this wonderful chem dissolved into a few ml of water. I decided I would put up this report as there appears to be literally no other accounts of it. The location I acquired it from suggested taking 2mg but I only took 1mg to be on the safe side.

    scraped 2026-03-14
    25b Nbome 400ug An Unintended Physical Reaction neutral

    Physical Background: I am overall physically healthy. -I have an ideal B.M.I. -I have stress related borderline hypertension. 130/80 mm/hg - 145/95 mm/hg -I am moderately physically active. I cycle one hour a day, walk one mile a day, and do very light strength training. -I have a balanced grain based diet.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Phenethylamines The Big & Dandy 25B-NBOMe (NBOMe-2C-B) Thread

    Welcome to The Big & Dandy 25B-NBOMe Thread 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine Reagent drug test info for NBOMe compounds External Links: Wikipedia Entry Isomer Design Entry 25X-NBOMe, 25X-NBOH SAFETY MESSAGE This is a newly discovered group of chemicals, with little history of human...

    Read full thread on Bluelight โ†’

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