T0:00 - Cut the tan powder into a line and snort it. I was expecting the nightmares of the other members of this family I had the displeasure of consuming (DPT and 4-HO-DPT), where large piles of the chalky and retchingly bitter stinging powder had to be sucked down. Those ones dosed in the 70-100 mg range.
4-AcO-DPT
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Depracetin, 4acodpt
Summary
4-AcO-DPT is a research chemical tryptamine first reported around 2012 that acts as a prodrug to 4-HO-DPT through rapid de-acetylation. User reports indicate relatively poor oral bioavailability; intranasal or rectal routes produce shorter but more efficient experiences at roughly half oral doses, though insufflation can cause sharp stinging. The compound produces colorful, fast-moving visuals with pronounced physical stimulation including tremor, jaw tension, and visceral body load, yet comparatively less mystical depth than classic psychedelics.
Perspectives
“This substance is miraculously mentally stimulating. It feels as though it has boundless potential for introspection, therapy, learning, and analytical thinking. Rational, logical and completely anchored.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-15mg | 15-25mg | 25-35mg | 35mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 30-60 min | 30-60 min | 1-2 hrs | 1-2 hrs |
| Insufflated | 5-10 min | 10-25 min | 30-60 min | 1-2 hrs |
| Rectal | 10-25 min | 20-40 min | 45-90 min | 1-2 hrs |
Effect Profile
5 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
4.4
Moderate
4/10
Moderate visuals with mild body load and headspace
Visual Intensity
×3
6
color enhancement
drifting
tracers
Headspace Depth
×3
4
introspection
time distortion
confusion
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
5
nausea
teeth grinding
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 5 Erowid experience reports
Positive Effects 7
Color Enhancement
100.0%
70%
Stimulation
100.0%
70%
Euphoria
60.0%
70%
Introspection
60.0%
70%
Empathy
60.0%
70%
Focus Enhancement
60.0%
70%
Tactile Enhancement
60.0%
70%
Adverse Effects 1
Anxiety
80.0%
70%
Combinations
Cross-Check 4-AcO-DPT with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 2 reports 2 neutral visit
Setting: a wilderness trail in the Southwestern U.S., on a gorgeous January afternoon. 20 milligrams 4-AcO-DPT fumarate is insufflated. Within minutes, I can feel an indescribable, perhaps slightly dissociative sensation creeping through my body, and I'm beginning to clearly disconnect from sobriety in a somewhat famil...
4-AcO-DPT's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 4-AcO-DPT? Let us know. Reports are reviewed by moderators — this is not posted publicly.