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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-MiPT

    Aliases: 4-ho, Ho-mipt, Miprocin, 4homipt, homipt

    Psychedelic Research-chemical

    Summary PsychonautWiki

    4-Hydroxy-N-methyl-N-isopropyltryptamine (also known as 4-HO-MiPT, and Miprocin) is a novel psychedelic substance of the tryptamine class that produces psilocybin-like psychedelic effects when administered. It is part of a series of psychedelic substituted tryptamines such as 4-AcO-DMT, 4-HO-MET, 4-HO-DiPT that are considered to produce variations of the core psychedelic effects typified by psilocin.

    Perspectives

    “4-HO-MiPT carries a gripping bodyload on the comeup, a turbulent ascent, but it quickly levels off in a delightful cognitive thunderstorm. This chemical has an essence of fire and life in it, it excites instinct and taps into something primal within the mind.”

    “I am stuck just part way on. There is some retinal activity with my eyes closed. Maybe I am a little light-headed, a little starry. Nothing much.”

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-15mg 15-25mg 25-35mg 35mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 12-48 min 18-60 min 1.5-2.5 hrs 1-2 hrs 2-12 hrs 3-6.3 hrs

    Effect Profile

    118 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 81 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations autonomous entities colour enhancement drifting synaesthesia tracers +9 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity feelings of interdependent opposites subconscious communication emotion enhancement perspective alterations +5 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination synaesthesia
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression teeth grinding
    Based on reports from:
    Effect Index The Essence of Bugs Effect Index A Delightfully Fun and Clear-Headed Psychedelic TiHKAL TiHKAL #22: 4-HO-MIPT Bluelight Big & Dandy Thread Erowid Experience Reports
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocybin
    85%
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects Erowid Bluelight

    Aggregated from 81 Erowid and 37 Bluelight experience reports

    Positive Effects 76

    Visual Distortions 67.8% 78%
    Music Enhancement 56.7% 88%
    Color Enhancement 50.0% 88%
    Closed-Eye Visuals 41.5% 90%
    Visual Trails 37.8% 89%
    Euphoria 36.4% 93%
    Empathy 33.1% 84%
    Introspection 27.1% 80%
    Tactile Enhancement 27.1% 83%
    Surface Breathing 27.0% 84%
    Joy 27.0% 88%
    Focus Enhancement 26.2% 80%
    Body High 22.9% 86%
    Open-Eye Visuals 22.9% 83%
    Contentment 21.6% 85%
    Awe 21.6% 79%
    Geometric Imagery 21.6% 86%
    Libido Enhancement 21.6% 84%
    Patterning 18.9% 86%
    Melting/flowing 16.2% 85%

    Adverse Effects 55

    Anxiety 45.7% 81%
    Body Load 40.5% 77%
    Auditory Effects 37.3% 82%
    Nausea 33.0% 79%
    Muscle Tension 32.2% 78%
    Confusion 25.4% 82%
    Sedation 22.0% 78%
    Dissociation 18.6% 82%
    Tremor 16.2% 81%
    Paranoia 16.2% 85%
    Thought Disorganization 16.2% 82%
    Jaw Clenching 14.4% 80%
    Motor Impairment 12.7% 77%
    Ego Dissolution 11.9% 85%
    Memory Suppression 11.9% 85%
    Headache 11.0% 80%
    Temporal Disorientation 10.8% 84%
    Depersonalization 10.8% 80%
    Fear 10.8% 85%
    Increased Heart Rate 9.9% 70%

    Combinations TripSit

    Trip Reports Effect Index

    The Essence of Bugs nervewing A Delightfully Fun and Clear-Headed Psychedelic froggie

    PiHKAL / TiHKAL Shulgin

    TiHKAL #22: 4-HO-MIPT

    “I am stuck just part way on. There is some retinal activity with my eyes closed. Maybe I am a little light-headed, a little starry. Nothing much.”

    — Alexander Shulgin, TiHKAL (with 9 mg, orally)
    4-HO-MiPT's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki 📖 Bluelight