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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-MPMI Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • partial dose data
    • duration data present
    • 18 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: Lucigenol

    Psychedelic Research-chemical

    Summary TripSit

    A rare tryptamine derivative first synthesised by David Nichols. This drug, also known as lucigenol, has rarely been documented outside the lab. It is known to be a psychedelic similar to other psychoactive tryptamines, with a potency similar to DOI, but little else is known.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 750ug-1mg 1-2mg - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak Total
    Oral 15-60 min 6-8 hrs 6-8 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 3.1
    Light+ 3/10

    Mild visuals with low body load and headspace

    Visual Intensity ×3
    4
    color enhancement brightened colour visual distortions
    Headspace Depth ×3
    2
    confusion time distortion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    3
    muscle tension increased heart rate
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 4-HO-MPMI
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    30%
    Tryptamines
    Psilocybin
    30%
    Psilocin
    30%
    DMT
    30%
    5-MeO-DMT
    30%
    Phenethylamines
    Mescaline
    30%
    2C-B
    30%
    2C-E
    30%

    Effects TripSit

    Positive
    • Mental/physical stimulation
    • Stimulation
    Negative
    • Pupil dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    • Increased heart rate
    Neutral
    • Decreased appetite
    • Sedation
    Positive
    • Euphoria
    • Empathy
    • Insight
    • Cognitive euphoria
    • Wakefulness
    Negative
    • Confusion
    • Anxiety
    Neutral
    • Change in perception
    • Ego softening
    • Time distortion
    Positive
    • Brightened colour
    • Enhanced tactile sensation
    • Color enhancement
    • Increased music appreciation
    Negative
    • Light sensitivity
    • Appetite suppression
    • Disinhibition
    Neutral
    • Closed/Open eye visuals
    • Visual distortions
    • Dulled perception

    Combinations TripSit

    Cross-Check 4-HO-MPMI with another substance

    4-HO-MPMI's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki