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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-MPT Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 4 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Tentative
    • classified Research-chemical

    Aliases: 4hompt

    Summary PsychonautWiki

    4-Hydroxy-N-methyl-N-propyltryptamine (also known as 4-HO-MPT or Meprocin) is a novel synthetic psychedelic substance of the tryptamine chemical class that produces psychedelic effects when administered. It is a closely related structural analog of 4-HO-DMT (Psilocin) and other hallucinogenic tryptamines with powerful psychedelic effects.

    Perspectives

    “There was a very mild visual distortion, and a prominent vertigo without nausea. In the second hour there is still some enhancement of visual detail, but I am not endowed with the flight of ideas of philosophical concepts as with psilocin. I am rapidly subsiding and I am able to eat normally. Residual insomnia lasted eight hours.”

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-20mg 20-30mg 30-50mg 50mg+
    Vapourized 3-5mg 5-10mg 10-15mg 15mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 18-60 min 1-2 hrs 2-3 hrs 1-2 hrs 2-12 hrs
    Vapourized 1 min - 45-90 hrs - 1-6 hrs

    Effect Profile

    6 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 7.0
    Strong+ 7/10

    Strong visuals and auditory effects with mild headspace and body load

    Visual Intensity ×3
    10
    color enhancement tracers drifting pattern recognition enhancement color shifting depth perception distortions +2 more
    Headspace Depth ×3
    4
    conceptual thinking personal bias suppression time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    Body Load / Somatic Effects ×1
    4
    nausea increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    30%
    Tryptamines
    Psilocin
    30%
    DMT
    30%
    5-MeO-DMT
    30%
    Phenethylamines
    Mescaline
    30%
    2C-B
    30%
    2C-E
    30%

    Effects Erowid

    Aggregated from 6 Erowid experience reports

    Positive Effects 6

    Euphoria 83.3% 70%
    Music Enhancement 66.7% 70%
    Color Enhancement 50.0% 70%
    Empathy 50.0% 70%
    Stimulation 50.0% 70%
    Tactile Enhancement 50.0% 70%

    Adverse Effects 2

    Anxiety 50.0% 70%
    Confusion 50.0% 70%

    Combinations TripSit

    Cross-Check 4-HO-MPT with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 4 reports 1 positive 3 neutral visit
    Vaporization positive exp #90809

    15mg vaporization 4-HO-MPT (freebase) T 0:00:00 Substance vaporized in glass over steel wool. T 0:00:05 Initial effects noted, coming strongly T 0:00:10 Becoming saturated in the material, closing eyes and anticipating what more is to come T 0:00:20 Feeling a dissolving, breakthrough experience.

    839823
    It Is Because It Is neutral exp #107131

    Well, I had hoped to keep some time log during this experience as I did my last one, but the nature of the trip prevented that sort of basic functioning from really being workable. Instead, I will just have to recall the events from memory as best I can.

    Kaleida · 25 mg oral / 2 bowls smoked
    Visuals But Not Much Else neutral exp #89739

    T+0.00: 16 mg 4-HO-MPT Freebase Age: 18 Weight: 128 lbs Gender: Male Prior substance use: Started doing drugs 8 months ago. Marijuana, Alcohol, Kratom, Nitrous, Shrooms, DMT, Salvia, Vicodin, Acid (likely not LSD), 4-Aco-DMT, Ketamine. I had smoked marijuana last night.

    jaggerjack · 16 mg oral
    Three Minutes Then My Mind Was Blown Apart neutral exp #90564

    Prior drug experiences: DMT, DPT, 4-HO-DiPT, MET, 4-AcO-DMT, LSD, 2C-B, 2C-D, psilocybin mushrooms, salvia divinorum, methamphetamine, amphetamine, 4-FA, methylone, MDMA, cocaine, cannabis, opium, opiates, etc.

    IpsoFacto · 8 mg smoked / smoked / oral

    Bluelight Reference Guide Bluelight

    Tryptamines The Big & Dandy 4-HO-MPT Thread

    Anyone have any experience at all with this material? TIHKAL notes of only one experience at 8mg in which There was a very mild visual distortion, and a prominent vertigo without nausea.

    Read full thread on Bluelight โ†’

    PiHKAL / TiHKAL Shulgin

    TiHKAL #23: 4-HO-MPT

    “There was a very mild visual distortion, and a prominent vertigo without nausea. In the second hour there is still some enhancement of visual detail, but I am not endowed with the flight of ideas of philosophical concepts as with psilocin. I am rapidly subsiding and I am able to eat normally. Residual insomnia lasted eight hours.”

    โ€” Alexander Shulgin, TiHKAL (with 8 mg, orally)

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