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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MeO-DET Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 17 combo interactions documented
    • classified Research-chemical

    Perspectives

    “It hit in a half hour, and the thought that came to mind was the phrase from my days at college, β€œBoy, I really felt that drink!”

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects

    Combinations

    Cross-Check 5-MeO-DET with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 1 report 1 neutral visit
    Potently Divine.... neutral exp #43242

    It was a planned assembly of friends, a gathering of 7 people. I had invited two of them to be introduced to Foxy (5-meo-dipt) by my friend (we'll call him steve). So they dosed as well as me with 20mg each.

    neon green snake · 20 mg / 50 mg insufflated

    PiHKAL / TiHKAL Shulgin

    TiHKAL #36: 5-MeO-DET

    “It hit in a half hour, and the thought that came to mind was the phrase from my days at college, β€œBoy, I really felt that drink!”

    β€” Alexander Shulgin, TiHKAL (with 2 mg, orally)

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