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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MeO-DiPT Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 17 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Foxy, Foxy methoxy, foxy-methoxy, 5meodipt

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    5-Methoxy-N,N-diisopropyltryptamine (also known as 5-MeO-DiPT, Foxy, and Foxy Methoxy) is a novel psychedelic substance of the tryptamine class that produces psychedelic effects when administered. It is related in structure to DiPT and 5-MeO-MiPT. The first human trials of 5-MeO-DiPT were undertaken by Alexander Shulgin in 1975. who would co-author and publish a paper detailing its synthesis and human psychopharmacology in 1981.

    Perspectives

    “Effects were present in twenty minutes, and I took my portable radio into the garden at forty minutes just to pull weeds. Each weed had special significance, and my cat Ms. joined me and agreed with me. This is excessively strange. The radio was discussing a President Ford fund-raiser, and continued with word sequences such as fund, fun, profun, profound, profane, refrain, and on and on. A car drove by with sitar music playing on its radio! Why not. And by my hour number three, I am back where I started. That was quite a morning.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 3-10mg 10-15mg 15-20mg 20mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-40 min 30-60 min 1-2 hrs 2-4 hrs 2-6 hrs 6-12 hrs
    Insufflated 4-19 min 15-30 min 45-90 min 1-3 hrs 2-4 hrs 4-8 hrs
    Smoked 1-4 min 4-10 min 30-90 min 1-2 hrs 2-6 hrs 4-8 hrs

    Effect Profile

    326 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 267 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.4
    Intense 8/10

    Strong visuals, auditory effects, body load, and headspace

    Visual Intensity ×3
    10
    color enhancement tracers drifting pattern recognition enhancement color shifting depth perception distortions +3 more
    Headspace Depth ×3
    9
    conceptual thinking personal bias suppression time distortion confusion
    Auditory Effects ×1
    10
    auditory distortions auditory distortion auditory hallucination
    Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction bodily pressures muscle tension increased heart rate
    Empathogen 8.3
    Intense 8/10

    Strong euphoria, stimulation, and sensory enhancement with moderate empathy

    Empathy / Social Openness ×3
    6
    empathy
    Euphoria / Mood Elevation ×2
    10
    cognitive euphoria euphoria emotional enhancement
    Stimulation ×1
    10
    stimulation restlessness increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement enhanced tactile sensation color enhancement visual acuity enhancement increased libido
    Stimulant 5.9
    Strong 6/10

    Strong anxiety/jitters and euphoria with moderate stimulation, mild focus

    Stimulation / Energy ×3
    7
    stimulation
    Euphoria / Mood Lift ×2
    9
    cognitive euphoria euphoria
    Focus / Productivity ×2
    4
    Anxiety / Jitters ×1
    10
    restlessness increased heart rate vasoconstriction muscle tension

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects Erowid Bluelight

    Aggregated from 267 Erowid and 59 Bluelight experience reports

    Positive Effects 68

    Color Enhancement 47.3% 85%
    Stimulation 44.1% 82%
    Music Enhancement 43.2% 85%
    Euphoria 38.8% 86%
    Tactile Enhancement 36.9% 86%
    Libido Enhancement 28.0% 86%
    Body High 27.4% 86%
    Focus Enhancement 24.9% 80%
    Patterning 24.0% 84%
    Joy 24.0% 86%
    Empathy 23.4% 78%
    Surface Breathing 20.0% 82%
    Visual Trails 20.0% 84%
    Introspection 18.0% 82%
    Closed-Eye Visuals 18.0% 87%
    Awe 16.0% 84%
    Sociability Enhancement 16.0% 84%
    Orgasm Enhancement 14.0% 86%
    Insight 14.0% 76%
    Melting/flowing 14.0% 83%

    Adverse Effects 60

    Body Load 50.0% 86%
    Nausea 37.9% 81%
    Anxiety 36.3% 84%
    Tremor 32.0% 82%
    Muscle Tension 27.8% 88%
    Confusion 25.6% 84%
    Focus Suppression 18.0% 77%
    Depersonalization 16.0% 81%
    Fear 16.0% 86%
    Insomnia 16.0% 77%
    Thought Loops 14.0% 79%
    Restlessness 14.0% 82%
    Thought Disorganization 14.0% 80%
    Heaviness 10.0% 82%
    Stomach Cramps 10.0% 76%
    Thought Acceleration 10.0% 81%
    Vomiting 10.0% 82%
    Vibrating 10.0% 84%
    Jaw Clenching 9.8% 81%
    Headache 8.5% 76%

    Combinations TripSit

    Cross-Check 5-MeO-DiPT with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Very Pleasant, but Extremely Intense positive exp #15177

    Preparation: I read the Tihkal report and several other reports online before trying this drug. I highly recommend doing the same, not just with this drug, but any. The most useful information for this experience was to go in with an empty stomach. The body load with this chemical is unbelieveably high.

    DJM · 12.5 mg oral / 9.4 mg oral
    A Universe I Call the 'FOX' positive exp #3384

    Received 5-MeO-DIPT in mail two days prior, mixed 250 mg. in with 250 ml. of purified water. Empty stomach except for a small salad and a nutrigrain bar at lunch. Open and clear mind. I'm in a good mood. 8:15 PM. Me and good friend J dose 10 ml. each mixed in with fruit juice.

    Q-tip · 10 mg oral
    A Vulpine Adventure positive exp #28543

    This was my first experience with Β‘foxy methoxyΒ’ and certainly will not be my last. My friend Giles had acquired large quantities of pure 5-MeO-DIPT from an online source. Before taking a new drug I would normally research it carefully, working out dosage, the expected effects, duration etc.

    Smoke & Mirrors · 22.5 mg oral
    Challenging Foxy Orthodoxy neutral exp #115045

    The following Greek letters have been changed to protect the innocent. This trip report is written by Theta. This was our second experience with 5-MeO-DiPT, and our first time smoking it.

    Kaleida · 5 mg smoked / repeated smoked
    A World of Difference neutral exp #21989

    BODY WEIGHT: 143bs Note: If you do this chemical and come down... good luck sleeping! I'm still up! and have I got a crazy story to tell... On a bright beautiful saturday afternoon in my college dormroom, I recieved a call (that I was awaiting) from a few friends of mine.

    The Hunted Cat
    Stoned, Ripped, Twisted... Good People neutral exp #15782

    After getting our Jollies by scaring the shit out of a church-going brother and a sister by chasing them around a parking in my mothers car void any headlights, My friends 'Green', 'Brown' and myself returned to our prearranged parking spot and continued waiting for our irresponsible Foxy dealer.

    Murdock
    Psychotic Episode & Temporary Organ Failure cautionary exp #27587

    I recently spent four days in the hospital because of a disastrous 5-meo-dipt trip that included a psychotic episode, temporary failure of my kidneys, and suspicion of heart problems.

    I Am LeBron · 25 mg oral
    Human Conscience and Chemical Intercourse cautionary exp #22261

    It had been a long time since I had touched a hallucinogenic substance. There was a reason I had quit doing them. As I lay in bed almost two years ago, unable to sleep after a horrible experience on a heavy dose of AMT, I knew that something had to change.

    Raoul · 35 mg oral

    Bluelight Reference Guide Bluelight

    Tryptamines The Big & Dandy 5-MeO-DiPT Thread

    Comparisons 5-MeO-MiPT vs 5-MeO-DiPT Combinations 5-MeO-DIPT & MDMA Original Post: Well I've taken 5-MeO-DiPT all ways but snorting now(and of course I've not plugged it thats just gross).....I've come to the conclusion that IV is the best route for 5-MeO-Dipt.

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    TiHKAL #37: 5-MeO-DIPT

    “Effects were present in twenty minutes, and I took my portable radio into the garden at forty minutes just to pull weeds. Each weed had special significance, and my cat Ms. joined me and agreed with me. This is excessively strange. The radio was discussing a President Ford fund-raiser, and continued with word sequences such as fund, fun, profun, profound, profane, refrain, and on and on. A car drove by with sitar music playing on its radio! Why not. And by my hour number three, I am back where I started. That was quite a morning.”

    β€” Alexander Shulgin, TiHKAL (with 6 mg, orally)

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