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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MeO-MET

    Psychedelic Research-chemical

    Summary TripSit

    An obscure psychedelic drug similar in structure to 5-MeO-DMT. Possibly first synthesised by Alexander Shulgin. Likely to have similar effects to other tryptamine psychedelics.

    Perspectives

    “This is a boring and uncomfortable drug when taken orally, underwhelming and underperforming in just about every conceivable way. The physical sensations consist primarily of discomfort and unease, with muscle aches, nausea, and excess stimulation. There is nothing remotely pleasant or enjoyable.”

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 13-15mg 15-25mg 25mg 25mg+
    Vapourized 1-5mg 5-8mg 8-12mg 12mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 10-45 min 2-3 hrs 1-2 hrs

    Effect Profile

    3 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 2.8
    Light+ 3/10

    Moderate body load with mild visuals, low headspace

    Visual Intensity ×3
    4
    color enhancement brightened colour visual distortions
    Headspace Depth ×3
    2
    confusion time distortion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    6
    nausea muscle tension increased heart rate
    Based on reports from:
    Effect Index A Cruel Prank Effect Index Surprisingly Nauseous and Disappointing Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 5-MeO-MET
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    30%
    Tryptamines
    Psilocybin
    30%
    Psilocin
    30%
    DMT
    30%
    5-MeO-DMT
    30%
    Phenethylamines
    Mescaline
    30%
    2C-B
    30%
    2C-E
    30%

    Effects Erowid

    Aggregated from 3 Erowid experience reports

    Positive Effects 0

    Adverse Effects 1

    Anxiety 100.0% 70%

    Combinations TripSit

    Trip Reports Effect Index

    A Cruel Prank nervewing Surprisingly Nauseous and Disappointing froggie
    5-MeO-MET's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 Bluelight 📖 PsychonautWiki