Home
    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Summary TheDrug.Wiki TripSit PsychonautWiki

    DOI is an extremely potent and long-lasting psychedelic with a very sensitive dose-response curve. It is sometimes sold falsely as LSD, which can be dangerous due to differing safety profiles and dosage ranges. Use a precise milligram scale for accurate dosing.

    Perspectives

    “There was a nice spacey light-headedness for a few hours, and time seemed to move quite slowly. Then a generic sadness came over me, as I reminisced about earlier days (recalling pleasures now gone) and wondered if I would be allowed to be here on the Farm when I am old and not important. There is so much to be done, and I cannot do it all, and no one else cares. My mood became present-day and healthy by about the seventh hour.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-2mg 2-3mg 3mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 1-2 hrs 1.5-3 hrs 3-6 hrs 6-12 hrs 24-48 hrs 16-30 hrs

    Effect Profile

    59 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 42 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.5
    Intense 8/10

    Strong visuals, headspace, body load, and auditory effects

    Visual Intensity ×3
    10
    visual geometry colour enhancement drifting tracers pattern recognition enhancement brightened colour
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement time distortion confusion
    Auditory Effects ×1
    8
    Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction muscle tension
    Stimulant 7.2
    Strong+ 7/10

    Strong stimulation, anxiety/jitters, and euphoria with mild focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    9
    cognitive euphoria euphoria
    Focus / Productivity ×2
    5
    thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety restlessness vasoconstriction muscle tension

    Tolerance

    Build-up develops rapidly; very long duration provides natural spacing
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    60%
    Tryptamines
    Psilocin
    65%
    DMT
    65%
    5-MeO-DMT
    65%
    Phenethylamines
    Mescaline
    85%
    2C-B
    85%
    2C-E
    85%

    Effects Erowid Bluelight

    Aggregated from 42 Erowid and 17 Bluelight experience reports

    Positive Effects 44

    Visual Distortions 55.9% 80%
    Stimulation 54.2% 82%
    Color Enhancement 35.6% 86%
    Euphoria 33.9% 86%
    Closed-Eye Visuals 28.8% 92%
    Music Enhancement 27.1% 80%
    Empathy 26.2% 70%
    Focus Enhancement 25.4% 85%
    Patterning 23.5% 90%
    Brightness Enhancement 23.5% 82%
    Entity Imagery 23.5% 85%
    Open-Eye Visuals 20.4% 88%
    Pareidolia 17.6% 82%
    Thought Acceleration 17.6% 83%
    Geometric Imagery 17.6% 88%
    Contentment 17.6% 82%
    Body High 17.0% 79%
    Introspection 16.9% 85%
    Ego Dissolution 13.6% 85%
    Tactile Enhancement 11.9% 85%

    Adverse Effects 41

    Anxiety 32.2% 88%
    Body Load 29.4% 86%
    Nausea 25.4% 85%
    Restlessness 23.5% 78%
    Muscle Tension 21.4% 70%
    Dry Mouth 17.6% 87%
    Jaw Clenching 11.9% 80%
    Paranoid Ideation 11.8% 85%
    Visual Trails 11.8% 90%
    Visual Vibration 11.8% 85%
    Thought Disorganization 11.8% 88%
    Fear 11.8% 88%
    Insomnia 11.8% 88%
    Time Dilation 11.8% 75%
    Ataxia 11.8% 78%
    Irritability 11.8% 82%
    Vomiting 11.8% 85%
    Tremor 11.8% 82%
    Emotional Lability 11.8% 80%
    Memory Suppression 9.5% 70%

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #67: DOI

    “There was a nice spacey light-headedness for a few hours, and time seemed to move quite slowly. Then a generic sadness came over me, as I reminisced about earlier days (recalling pleasures now gone) and wondered if I would be allowed to be here on the Farm when I am old and not important. There is so much to be done, and I cannot do it all, and no one else cares. My mood became present-day and healthy by about the seventh hour.”

    β€” Alexander Shulgin, PiHKAL (with 0.6 mg)

    Helpful Links