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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Summary TheDrug.Wiki TripSit PsychonautWiki

    DOI is an extremely potent and long-lasting psychedelic with a very sensitive dose-response curve. It is sometimes sold falsely as LSD, which can be dangerous due to differing safety profiles and dosage ranges. Use a precise milligram scale for accurate dosing. The exceptionally long duration of 16-24 hours with residual stimulation lasting up to 48 hours requires adequate time preparation. Individuals with personal or family history of psychotic disorders should avoid use.

    Perspectives

    “There was a nice spacey light-headedness for a few hours, and time seemed to move quite slowly. Then a generic sadness came over me, as I reminisced about earlier days (recalling pleasures now gone) and wondered if I would be allowed to be here on the Farm when I am old and not important. There is so much to be done, and I cannot do it all, and no one else cares. My mood became present-day and healthy by about the seventh hour.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-2mg 2-3mg 3mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 1.0-2.0 hrs 1.5-3.0 hrs 3.0-6.0 hrs 6.0-12.0 hrs 24.0-48.0 hrs 16.0-30.0 hrs

    Tolerance

    Build-up develops rapidly; very long duration provides natural spacing
    Reset 7–14 days for baseline

    Effects TheDrug.Wiki TripSit

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Nausea
    • Vasoconstriction
    • Pupil Dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    Neutral
    • Muscle Contractions
    • Decreased appetite
    Positive
    • Thought Connectivity
    • Conceptual Thinking
    • Empathy Enhancement
    • Cognitive Euphoria
    • Emotion Enhancement
    • Wakefulness
    • Euphoria
    • Empathy
    • Insight
    Negative
    • Anxiety
    • Confusion
    Neutral
    • Thought Acceleration
    • Time Distortion
    • Change in perception
    • Ego softening
    Positive
    • Bodily Control Enhancement
    • Tactile Enhancement
    • Colour Enhancement
    • Pattern Recognition Enhancement
    • Visual Geometry
    • Tracers
    • Increased Music Appreciation
    • Brightened colour
    • Enhanced tactile sensation
    Negative
    Neutral
    • Spontaneous Physical Sensations
    • Drifting
    • Internal Hallucination
    • External Hallucination
    • Closed/Open eye visuals

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #67: DOI

    “There was a nice spacey light-headedness for a few hours, and time seemed to move quite slowly. Then a generic sadness came over me, as I reminisced about earlier days (recalling pleasures now gone) and wondered if I would be allowed to be here on the Farm when I am old and not important. There is so much to be done, and I cannot do it all, and no one else cares. My mood became present-day and healthy by about the seventh hour.”

    β€” Alexander Shulgin, PiHKAL (with 0.6 mg)

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