- Dose: 400mcg (+/- 50mcg) - ROA: Nasal (via nasal spray bottle) - Set/setting: My home during a weekday, in good spirits. - Tolerance: Dosed 250mcg a week prior. It's 10am on a Monday, I had awoken an hour before with plans to trip today.
25E-NBOMe
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- classified Research-chemical
Aliases: 25e
Summary
A potent psychedelic phenethylamine and derivative of 2C-E, usually sold on blotters. May be mis-sold as LSD. Effects include vivid hallucinations, stimulation, heavy body load and vasoconstriction.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 150-300ug | 300-600ug | 600-1000ug | 1000ug+ |
| Insufflated | 50-200ug | 200-400ug | 400-800ug | 800µg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Sublingual | 15-60 min | 5-10 hrs | 5-10 hrs |
Effect Profile
3 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
2.8
Light+
3/10
Moderate body load with mild visuals, low headspace
Visual Intensity
×3
4
color enhancement
brightened colour
visual distortions
Headspace Depth
×3
2
confusion
time distortion
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
6
nausea
muscle tension
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use; redosing is especially dangerous
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 3 Erowid experience reports
Positive Effects 1
Color Enhancement
100.0%
70%
Adverse Effects 1
Anxiety
100.0%
70%
Combinations
Cross-Check 25E-NBOMe with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 3 reports 3 neutral visit
- Dose: 250mcg - ROA: Nasal (via nasal spray bottle) - Set/Setting: my home in a private bar/barn at the end of our property. My friend brought me the bottle late on this night, we had worked out a trade as we often do. It was my first attempt with an nbome as I'd avoided dosing them up until this point.
This is my account of 25E-NBOMe. I have tried 25E-NBOH (a structurally similar substance) before at dosages ranging from 1.8mg to 3.6mg (I prefer 1.8mg overall) and I generally like that one a lot.
25E-NBOMe's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 25E-NBOMe? Let us know. Reports are reviewed by moderators — this is not posted publicly.