Home
    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2-FDCK

    Aliases: 2-fk, 2f-ket, 2f-ketamine, Fluoroketamine, 2-fl-2'-oxo-pcm, 2-fluorodeschloroketamine, 2f-dck, 2fket, 2fdck

    Dissociative Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    2-Fl-2'-Oxo-PCM (also known as 2-Fluorodeschloroketamine, 2-FDCK, and inaccurately as 2-Fluroketamine, Fluoroketamine, and 2-FK and known as CAS number: 111982-50-4) is a lesser-known novel dissociative substance of the arylcyclohexylamine class. It is chemically similar to ketamine and deschloroketamine (DCK). It is thought to act as an NMDA receptor antagonist, although research is currently limited.

    Perspectives

    “It’s amazing just how much changing the ROA can change a drug. This frankly felt like a totally different substance than when it is dosed intranasally. There was absolutely zero rush with the oral ROA, it was a steady and certain immersion into the experience.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Insufflated BA ~50% 10-45mg 45-100mg 100-175mg 175mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral / Sublingual 15-60 min 45-90 min 1-2 hrs 1-2 hrs 1-6 hrs 3-5 hrs
    Insufflated 4-19 min 15-45 min 1-2 hrs 1-2 hrs 1-6 hrs 2-4 hrs
    Intramuscular 4-10 min 10-19 min 1-2 hrs 1-2 hrs 1-6 hrs 2-4 hrs
    Rectal 10-30 min 30-60 min 1-2 hrs 1-2 hrs 1-6 hrs 2.5-4.5 hrs

    Effect Profile

    17 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 5.4
    Moderate+ 5/10

    Strong dissociative depth, motor impairment, and mania with low insight

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection visual disconnection spatial disorientation memory suppression
    ⚠ Mania / Compulsion ×1
    8
    compulsive redosing disinhibition stimulation
    Insight / Novel Thought ×2
    3
    conceptual thinking
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more
    Based on reports from:
    Effect Index Entombed in Syrup Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 2-FDCK
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives
    Ketamine
    80%
    Dextromethorphan
    80%
    PCP
    80%
    Methoxetamine
    80%
    3-MeO-PCP
    80%
    3-HO-PCP
    80%
    3-MeO-PCE
    80%
    3-HO-PCE
    80%

    Effects Erowid

    Aggregated from 17 Erowid experience reports

    Positive Effects 8

    Music Enhancement 58.8% 70%
    Euphoria 52.9% 70%
    Color Enhancement 52.9% 70%
    Empathy 41.2% 70%
    Focus Enhancement 35.3% 70%
    Stimulation 35.3% 70%
    Tactile Enhancement 29.4% 70%
    Body High 29.4% 70%

    Adverse Effects 6

    Anxiety 58.8% 70%
    Motor Impairment 35.3% 70%
    Nausea 29.4% 70%
    Confusion 23.5% 70%
    Headache 17.6% 70%
    Increased Heart Rate 17.6% 70%

    Combinations TripSit

    Trip Reports Effect Index

    Entombed in Syrup nervewing
    2-FDCK's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 Bluelight 📖 PsychonautWiki