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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-AcO-MET Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Metacetin, 4-acetoxy-met, O-acetylmetocin, 4acomet

    Psychedelic Research-chemical

    Summary PsychonautWiki

    4-Acetoxy-N-methyl-N-ethyltryptamine (also known as 4-AcO-MET, Metacetin, and Azomet) is a lesser-known novel psychedelic substance of tryptamine class. Members of this group produce psilocybin-like psychedelic effects when administered. It is structurally related to psychedelic tryptamines like 4-AcO-DMT, 4-AcO-DET, and 4-AcO-MiPT.

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-20mg 20-30mg 30-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 18-60 min 30-60 min 1-2 hrs 2 hrs 2-4 hrs 4-6 hrs

    Effect Profile

    36 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 23 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    internal hallucinations autonomous entities colour enhancement drifting tracers colour shifting +6 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity feelings of interdependent opposites subconscious communication emotion enhancement perspective alterations +5 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea muscle tension teeth grinding
    Based on reports from:
    Effect Index Resplendent and Warm Effect Index Dying from a Cosmic Slap Effect Index Warm and Arrogant Feeling Bluelight Big & Dandy Thread Erowid Experience Reports
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocybin
    85%
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects Erowid Bluelight

    Aggregated from 23 Erowid and 13 Bluelight experience reports

    Positive Effects 50

    Color Enhancement 69.5% 89%
    Stimulation 60.9% 70%
    Closed-Eye Visuals 55.6% 92%
    Patterning 53.8% 87%
    Empathy 52.2% 70%
    Focus Enhancement 47.8% 70%
    Euphoria 47.2% 89%
    Music Enhancement 47.2% 88%
    Open-Eye Visuals 44.4% 90%
    Introspection 41.7% 82%
    Entity Imagery 38.5% 86%
    Geometric Imagery 38.5% 88%
    Contentment 38.5% 78%
    Joy 30.8% 89%
    Morphing 30.8% 86%
    Surface Breathing 30.8% 84%
    Warping 23.1% 85%
    Awe 23.1% 83%
    Peace 23.1% 82%
    Tactile Enhancement 19.5% 75%

    Adverse Effects 25

    Anxiety 38.9% 83%
    Sedation 36.1% 82%
    Nausea 33.4% 88%
    Thought Disorganization 30.8% 76%
    Confusion 25.0% 85%
    Body Load 23.1% 78%
    Chills 23.1% 77%
    Sweating 16.6% 75%
    Thought Acceleration 15.4% 78%
    Fear 15.4% 75%
    Insomnia 15.4% 82%
    Dysphoria 15.4% 78%
    Headache 13.9% 80%
    Increased Heart Rate 13.0% 70%
    Jaw Clenching 13.0% 70%
    Pressure 7.7% 80%
    Memory Suppression 7.7% 80%
    Focus Suppression 7.7% 85%
    Panic 7.7% 75%
    Paranoid Ideation 7.7% 85%

    Combinations TripSit

    Cross-Check 4-AcO-MET with another substance

    Trip Reports Effect Index

    Resplendent and Warm nervewing Dying from a Cosmic Slap froggie Warm and Arrogant Feeling froggie

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 6 neutral 2 cautionary visit
    A Socialite's Delight neutral exp #117007

    I wake up on a crisp and sunny Saturday morning feeling somewhat groggy and out of place. Although a bit unfortunate, I have planned to have a psychedelic experience for some weeks on this day, and I am undeterred by the minor inconvenience.

    Ermine Bastard
    Opalescent Undersea Tunnels neutral exp #114067

    T0:00- Eat my dose. I am in a park near one of the major rivers that delineates the boundaries of the city. It is an unseasonably warm overcast day. T0:18- Feeling tension in my jaw and my muscles. Chew some gum. I decide to go for a walk across the big bridge that spans the river.

    nervewing · 30 mg oral / repeated smoked
    Eyes Closed Mind Open neutral exp #104063

    On an oval wood table next to my bed is a cup containing 30-35mg 4-aco-met. The scale said 33mg. I have consumed this compound in the 15 to 20mg range 3-5 times before. The settings of these experiences have always been around people or in a social environment.

    thewhitecrx
    A Child On A Mountain neutral exp #111503

    This was my first time taking 4-AcO-MET. My experience with psychedelics: 2x LSA (HBW seeds) I decided to go on a hiking trip, alone. I chose a route that I know well so that I don't have to worry about finding home. I was excited about the trip and my mood was good that morning.

    MountainChild · 30 mg oral / inhaled
    Beginner Friendly neutral exp #110097

    4-AcO-MET - 25mg Orally Setting: Monday afternoon, after getting off work. At approximately 4pm, I ingest 25mg of 4-AcO-MET on an empty stomach. 0:00 - I ingest 4-AcO-MET and smoke weed with my girlfriend while she compiles a shopping list of food for the week.

    MrMoran · 25 mg oral / smoked
    The Azoversary neutral exp #119383

    Taken as part of my visit, in a friend group, of a multi-day Goa festival. After a bad 2C-B trip the day before, I wanted to have a good time. I knew of my previous experience that 4-AcO-MET has a profound impact on me even at the supposedly "light" 15 mg dose.

    GMCat · 1 cup oral / 1 cup oral / 15 mg oral
    The Color of God Stabbed My Soul cautionary exp #111714

    I have jammed a bunch of alphabet soup into every available orifice for a while now, and taking a Β“threshold to lightΒ” dose of 10 mg of 4 AcO MET had me pretty well beyond anything ever, really. It must be a genetic match, my brain and that shit, let me tell you boy howdy.

    CorvallisJoe · 10 mg oral
    A Pleasant Foray cautionary exp #114813

    Background: I recently have been intrigued by 4 substituted tryptamines. Despite my previously horrible experiences with even low doses of mushrooms (in the ~1g range), 4-AcO-MET caught my eye due to its anecdotally clear head space and LSD like visuals.

    BigData · 13 mg oral / oral

    Bluelight Reference Guide Bluelight

    Tryptamines The Big & Dandy 4-AcO-MET Thread

    I recently gave a friend of mine some of this compound (the fumurate) and I asked him to write a trip report. If anyone has any information whatsoever or experiences with this stuff feel as free as a birdy to add to this thread.

    Read full thread on Bluelight β†’
    4-AcO-MET's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    πŸ“˜ Experience Reports πŸ“– TripSit πŸ“– PsychonautWiki πŸ“– Bluelight