4-HO-DET
Aliases: Cz-74, Homet, 4homet, Colour, Ethocin, 4hodet, 4-hydroxy-det
Summary
4-HO-DET is a research chemical with very little history of human usage. The toxicity and long-term health effects have not been studied in any scientific context. Compared to psilocin, 4-HO-DET has been reported to have a slightly longer duration, less pronounced bodily effects, and more synthetic or algorithmic-style visuals.
Perspectives
“This is perhaps one of the more boring psychedelics I have tasted. The experience does not lend itself to any meaningful thought processes or profound explorations of existence.”
“This was in a gelatin capsule and it came on from a half hour to the three-quarter hour point like gang-busters. Time really slowed down, with sparkly-ness, interesting, and yet there was a touch of sadness. The intense visuals held the scene, and there was the compulsion to talk and to interact and to share stuff, but the erotic was not to be found. I slept OK but there was something uncomfortable at a deep level. Am OK.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-15mg | 20-30mg | 30-45mg | 45mg+ |
| Intravenous | 5mg | 10-15mg | 20mg | 20mg+ |
| Smoked | 10-25mg | 25-35mg | 35-60mg | 60mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-45 min | 30-60 min | 2.5-3.5 hrs | 1.5-2 hrs | 3-7 hrs |
| Intravenous | 1-3 min | - | - | - | 1-3 min |
Effect Profile
18 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals, headspace, auditory effects, and body load
Tolerance
Tolerance Decay
Effects
Aggregated from 18 Erowid experience reports
Positive Effects 9
Adverse Effects 5
Combinations
Trip Reports
PiHKAL / TiHKAL
“This was in a gelatin capsule and it came on from a half hour to the three-quarter hour point like gang-busters. Time really slowed down, with sparkly-ness, interesting, and yet there was a touch of sadness. The intense visuals held the scene, and there was the compulsion to talk and to interact and to share stuff, but the erotic was not to be found. I slept OK but there was something uncomfortable at a deep level. Am OK.”