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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-DET

    Aliases: Cz-74, Homet, 4homet, Colour, Ethocin, 4hodet, 4-hydroxy-det

    Categories

    4-HO-DET structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    4-HO-DET is a research chemical with very little history of human usage. The toxicity and long-term health effects have not been studied in any scientific context. Compared to psilocin, 4-HO-DET has been reported to have a slightly longer duration, less pronounced bodily effects, and more synthetic or algorithmic-style visuals. It is strongly recommended to use harm reduction practices when using this substance. Legal status varies by jurisdiction; it is unscheduled in the United States but may be prosecuted under the Federal Analogue Act.

    Perspectives

    “This is perhaps one of the more boring psychedelics I have tasted. The experience does not lend itself to any meaningful thought processes or profound explorations of existence.”

    “This was in a gelatin capsule and it came on from a half hour to the three-quarter hour point like gang-busters. Time really slowed down, with sparkly-ness, interesting, and yet there was a touch of sadness. The intense visuals held the scene, and there was the compulsion to talk and to interact and to share stuff, but the erotic was not to be found. I slept OK but there was something uncomfortable at a deep level. Am OK.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-15mg 20-30mg 30-45mg 45mg+
    Intravenous 5mg 10-15mg 20mg 20mg+
    Smoked 10-25mg 25-35mg 35-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-45 min 30-60 min 2.5-3.5 hrs 1.5-2.0 hrs 1.0-4.0 hrs 3.0-7.0 hrs
    Intravenous 30.0-60.0 hrs - - - 1.0-12.0 hrs 3.0-7.0 hrs
    Smoked 0 min - - - 1.0-12.0 hrs 3.0-7.0 hrs

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Creativity Enhancement
    • Mental/physical stimulation
    • Spontaneous tactile sensations
    Negative
    • Temperature Regulation Suppression
    • Pupil Dilation
    • Watery Eyes
    • Increased Heart Rate
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    • Nausea
    • Runny nose
    • Seizure
    • Teeth grinding
    Neutral
    • Excessive Yawning
    • Frequent Urination
    • Decreased appetite
    • Spontaneous bodily sensations
    • Muscle contractions
    • Increased salivation
    Positive
    • Analysis Enhancement
    • Thought Connectivity
    • Conceptual Thinking
    • Euphoria
    • Empathy
    • Insight
    • Emotion enhancement
    • Immersion enhancement
    • Novelty enhancement
    • Unity and interconnectedness
    • Wakefulness
    • Laughter fits
    • Increased sense of humor
    • Immersion intensification
    Negative
    • Memory Suppression
    • Confusion
    • Delusions
    • Thought loops
    • Delusion
    • Brain zaps
    Neutral
    • Depth Perception Distortions
    • Perspective Distortions
    • Time Distortion
    • Ego Death
    • Change in perception
    • Ego softening
    • Personal bias suppression
    • Perspective alterations
    • Thought acceleration
    • Machinescapes
    • Perspective distortion
    • Thought loop
    • Recursion
    • Perception of interdependent opposites
    • Existential self-realization
    • Spirituality intensification
    Positive
    • Bodily Control Enhancement
    • Tactile Enhancement
    • Colour Enhancement
    • Pattern Recognition Enhancement
    • Visual Acuity Enhancement
    • Tracers
    • Colour Shifting
    • Increased Music Appreciation
    • Auditory Enhancement
    • Brightened colour
    • Enhanced tactile sensation
    • Acuity enhancement
    • Color enhancement
    • Color shifting
    • Auditory acuity enhancement
    • Synaesthesia
    Negative
    Neutral
    • Spontaneous Physical Sensations
    • Drifting
    • Colour Tinting
    • Symmetrical Texture Repetition
    • Internal Hallucination
    • External Hallucination
    • Auditory Distortion
    • Closed/Open eye visuals
    • Auditory hallucinations
    • Autonomous entities
    • Internal hallucinations
    • Auditory hallucination
    • Autonomous entity
    • Olfactory hallucination
    • Color tinting
    • Perspective hallucination
    • Tactile intensification
    • Scenery slicing
    • Changes in felt bodily form
    • After images
    • Environmental patterning

    Combinations TripSit

    Trip Reports Effect Index

    PiHKAL / TiHKAL Shulgin

    TiHKAL #16: 4-HO-DET

    “This was in a gelatin capsule and it came on from a half hour to the three-quarter hour point like gang-busters. Time really slowed down, with sparkly-ness, interesting, and yet there was a touch of sadness. The intense visuals held the scene, and there was the compulsion to talk and to interact and to share stuff, but the erotic was not to be found. I slept OK but there was something uncomfortable at a deep level. Am OK.”

    โ€” Alexander Shulgin, TiHKAL (with 15 mg indolol, orally)

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