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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-DiPT Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: Iprocin

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    4-HO-DiPT is a research chemical with very limited history of human use and no scientific studies on its toxicity. It is noted for its uniquely rapid onset, short duration, narrow dose sensitivity, and high intensity relative to dose. Physical side effects including muscle tremors, leg tremors, bodily malaise, and temperature dysregulation are commonly reported.

    Perspectives

    “A fairly standard tryptamine experience, with the relative strength of the various sensory effects adjusted. The cognitive effects were notable and heavy, while the visual effects were light, manifesting mostly as colorful ripples. No auditory effects were noted, and the short duration was also distinctive.”

    “I feel it in my legs! Within the hour I have leg tremors, a mild physical awareness for another hour. Mentally, probably nothing.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 3-10mg 10-20mg 20-30mg 30mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-30 min 20-40 min 60-90 min 30-60 min 1-3 hrs 2-4 hrs

    Effect Profile

    53 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 53 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    colour enhancement autonomous entities drifting tracers colour shifting pattern recognition enhancement +5 more
    Headspace Depth ×3
    10
    conceptual thinking introspection thought connectivity emotion enhancement perspective distortions personal bias suppression +2 more
    Auditory Effects ×1
    10
    auditory distortion auditory hallucination
    Body Load / Somatic Effects ×1
    10
    nausea muscle tension increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects Erowid

    Aggregated from 53 Erowid experience reports

    Positive Effects 10

    Euphoria 56.6% 70%
    Stimulation 56.6% 70%
    Music Enhancement 54.7% 70%
    Empathy 41.5% 70%
    Tactile Enhancement 39.6% 70%
    Color Enhancement 35.8% 70%
    Focus Enhancement 30.2% 70%
    Body High 24.5% 70%
    Introspection 22.6% 70%
    Creativity Enhancement 9.4% 70%

    Adverse Effects 9

    Anxiety 47.2% 70%
    Nausea 35.8% 70%
    Confusion 26.4% 70%
    Muscle Tension 22.6% 70%
    Memory Suppression 7.5% 70%
    Headache 7.5% 70%
    Pupil Dilation 7.5% 70%
    Jaw Clenching 5.7% 70%
    Motor Impairment 5.7% 70%

    Combinations TripSit

    Cross-Check 4-HO-DiPT with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 2 positive 4 neutral 2 cautionary visit
    Pure Magic positive exp #25600

    10:16 pm Initial effects from 25 mg ingested fifteen minutes beforehand. Getting that warm mystic rhythm and tingly sensation. Can tell this is going to be good. Things starting to move around. Been 15 minutes since I dosed. Music seems more dimensional and the bass flows through me like wine.

    gravol · 25 mg oral / 25 mg oral
    Life and Life positive exp #53923

    My dad had just left for the night and I had recently acquired some of this magic powder from an online store. This stuff is something for everyone. I love this stuff so much. The night started and I had just taken 25mgs put it into a piece of napkin and parachuted it down.

    Nickmp88 · 25 mg oral
    Complete and Total Oneness neutral exp #25165

    July 4th, 2003 24 mg of 4-Ho-DIPT (4-hydroxy-N,N-diisopropyltryptamine hydrochloride, Iprocin) It is the Fourth of July and no freelance fireworks are allowed in my town due to the significant drought the state is experiencing.

    Morninggloryseed · 4-Ho-DiPT
    Challenging But Fascinating neutral exp #106271

    It had been eight days since my previous trip, a weak experience on 36 mg of DiPT, and I didn't think there would be any tolerance issues. This was to be my first time trying 4-HO-DiPT by itself, with my only experience it so far coming from mixing it with LSD once at 25 mg.

    Goddess Mode · 30 mg oral / smoked
    Unexpected Encounters neutral exp #75917

    Weight : 150 lbs I have been experimenting with iprocin during the last month. I have tried it at 2, 7, 14, 25 and 30 mg. In the threshold range, it didnย’t produce any significant effects.

    DemonSeed · 40 mg oral
    Encounter with Death neutral exp #52266

    I acquired some 4-Hydroxy-DiPT from a friend, he bought them of the internet just before they became illegal (around may last year I think). I had also gotten a hit of acid from him, which was my first trip.

    Rood
    Crazy Combo with a Crazy Trip cautionary exp #38645

    [Erowid Note: Driving while intoxicated, tripping, or extremely sleep deprived is dangerous and irresponsible because it endangers other people. Don't do it! ] Ok here it goes... Let me first start off by saying that none of this is exaggerated.

    Crazy College Kids · 20 ml oral / 3 tablets oral / 2 tablets oral / 1 tablet oral
    Iridescent Ripples cautionary exp #114019

    T0:00- Dose administered T0:22- Not feeling much beyond the typical psychedelic onset, a sense of anxiety and nausea and tension climbing my limbs. T0:24- A distinct chill has set in and my limbs are being rocked by a steady wave of tremors, which is fairly typical of every psychedelic comeup for me.

    nervewing · 27 mg oral / repeated smoked
    Bluelight 2 threads 2 neutral visit
    Iprocin 40 Mg Experienced Unexpected Encounter neutral

    Unexpected encounter Iprocin โ€‹ DOSE : 40 mg oral iprocin parachuted Weight : 150 lbs I have been experimenting with iprocin during the last month. I have tried it at 2, 7, 14, 25 and 30 mg. In the threshold range, it didn't produces any significant effects.

    scraped 2026-03-14
    Iprocin 3rd Time Currents neutral

    42mg iprocin at ~23.20 in a capsule. I take garbage out and go biking at the same time. I get to that old railway bridge when I realize my tire has flattened. I have to walk home. It has been almost an hour since I swallowed the capsule and clearly that chemical has made its way to my serotonin receptors now.

    scraped 2026-03-14

    PiHKAL / TiHKAL Shulgin

    TiHKAL #17: 4-HO-DIPT

    “I feel it in my legs! Within the hour I have leg tremors, a mild physical awareness for another hour. Mentally, probably nothing.”

    โ€” Alexander Shulgin, TiHKAL (with 10 mg, orally)

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