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    Disclaimer
    ⚠ This substance involves MAOI activity. Dangerous interactions can occur with many common foods and medications. Research contraindications thoroughly.

    Ayahuasca

    Aliases: Aya, Cipó, Yage, Yaje, Brew, pharmahuasca

    Categories

    Psychedelic Stimulant Empathogen
    Ayahuasca structure

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Ayahuasca is a brew combining DMT-containing plants with MAOI-containing plants, requiring both components to produce psychoactive effects. Traditional brews vary widely in potency depending on plant sources, preparation methods, and regional practices. The purgative effects (nausea, vomiting, diarrhea) are considered an integral part of the traditional experience and can be intense. Due to the MAOI component, numerous dangerous drug interactions exist, particularly with SSRIs, other antidepressants, stimulants, and certain foods when using irreversible MAOIs. Harmala alkaloids from Syrian rue or B.

    Dose Information TheDrug.Wiki PsychonautWiki TripSit

    ROA Light Common Strong Heavy
    Oral (Traditional B. Caapi + P. Viridis Brew) Smallcup(50-75mloftraditionalbrew) - Largecup(150-200mloftraditionalbrew) Multipleservingsorveryconcentratedbrew+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki PsychonautWiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral (Syrian Rue + Mimosa Hostilis) 19-60 min 30-60 min 1.0-2.0 hrs 1.0-2.0 hrs 1.0-8.0 hrs 5.0-10.0 hrs
    Oral (Syrian Rue + Acacia Confusa) 19-60 min 30-60 min 1.0-2.0 hrs 1.0-2.0 hrs 1.0-8.0 hrs 4.0-8.0 hrs
    Oral (Pharmahuasca - Extracted Alkaloids) 15-30 min 19-40 min 1.0-2.0 hrs 1.0-2.0 hrs 1.0-6.0 hrs 4.0-8.0 hrs
    Oral (Traditional B. Caapi + P. Viridis Brew) 19-60 min 30-60 min 1.0-2.0 hrs 1.0-2.0 hrs 1.0-8.0 hrs 4.0-8.0 hrs
    Oral 18-60 min - 1.0-2.0 hrs 1.0-2.0 hrs 1.0-8.0 hrs 4.0-8.0 hrs

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline
    Cross-tolerance
    LSD Psilocybin Psilocin Mescaline DMT 5-MeO-DMT 2C-B 2C-E

    Effects TheDrug.Wiki TripSit

    Positive
    • Mental/physical stimulation
    • Creativity enhancement
    • Spontaneous tactile sensations
    • Stimulation
    Negative
    • Nausea
    • Physical discomfort
    • Pupil dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    • Diarrhea
    Neutral
    • Decreased appetite
    • Sedation
    Positive
    • Spiritual insight and mystical experiences
    • Unity and interconnectedness
    • Spirituality enhancement
    • Emotion enhancement
    • Emotional amplification and catharsis
    • Synesthesia
    • Mindfulness
    • Analysis enhancement
    • Catharsis
    • Euphoria
    • Empathy
    • Insight
    • Conceptual thinking
    • Immersion enhancement
    • Novelty enhancement
    • Personal meaning enhancement
    • Rejuvenation
    • Thought connectivity
    Negative
    • Confusion
    • Delusions
    • Language suppression
    • Memory suppression
    Neutral
    • Autonomous entity contact
    • Existential self-realization
    • Ego death
    • Time distortion
    • Change in perception
    • Ego softening
    • Feelings of eternalism
    • Feelings of interdependent opposites
    • Feelings of self-design
    • Personal bias suppression
    • Personality regression
    • Perspective alterations
    • Subconscious communication
    • Thought acceleration
    • Thought organization
    Positive
    • Brightened colour
    • Enhanced tactile sensation
    • Acuity enhancement
    • Auditory enhancement
    • Colour enhancement
    • Colour shifting
    • Pattern recognition enhancement
    • Synaesthesia
    Negative
    Neutral
    • Intense visual hallucinations and patterns
    • Internal hallucination
    • External hallucination
    • Spontaneous physical sensations
    • Closed/Open eye visuals
    • After images
    • Auditory distortion
    • Auditory hallucinations
    • Autonomous entities
    • Drifting
    • Internal hallucinations
    • Magnification
    • Scenery slicing
    • Symmetrical texture repetition

    Combinations TripSit

    Trip Reports Effect Index

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    Helpful Links

    📘 Experience Reports 📖 PsychonautWiki 📖 TripSit 📖 Bluelight 📖 The Drug Users Bible