Opioid Scale
109 substances mapped across opioid dimensions
Opioid Intensity Spectrum
0 — None
5 — Moderate
10 — Extreme
1
Threshold
Barely perceptible effects that may be placebo.
2
Light
Subtle effects that are clearly present but mild.
3
Light+
Noticeable effects that remain easy to manage.
4
Moderate
Clearly defined effects that shape the experience.
5
Moderate+
Pronounced effects that are hard to ignore.
6
Strong
Dominant effects that strongly influence the experience.
7
Strong+
Powerful effects that can become overwhelming at times.
8
Intense
Very powerful effects approaching peak intensity.
9
Intense+
Near-maximum intensity with little room above.
10
Extreme
Maximum intensity — effects dominate the experience entirely.
All Substances
Showing 5 of 109
| # | Substance | Intensity | Reports |
|---|---|---|---|
| 1 | Tramadol | 8.1 Intense | 403 |
| 2 | Heroin | 8.6 Intense+ | 377 |
| 3 | Oxycodone | 7.0 Strong+ | 350 |
| 4 | Hydrocodone | 8.0 Intense | 266 |
| 5 | Codeine | 8.3 Intense | 198 |
| 6 | Buprenorphine | 8.1 Intense | 152 |
| 7 | Methadone | 8.3 Intense | 149 |
| 8 | Opium | 6.6 Strong+ | 147 |
| 9 | Morphine | 6.9 Strong+ | 137 |
| 10 | Fentanyl | 7.6 Intense | 108 |
| 11 | L-Tryptophan | 3.9 Moderate | 101 |
| 12 | Oxymorphone | 8.1 Intense | 71 |
| 13 | Hydromorphone | 8.3 Intense | 70 |
| 14 | Olanzapine | 4.9 Moderate+ | 60 |
| 15 | Naloxone | 6.6 Strong+ | 46 |
| 16 | Tapentadol | 8.6 Intense+ | 23 |
| 17 | Pethidine | 7.6 Intense | 19 |
| 18 | Tianeptine | 5.0 Moderate+ | 17 |
| 19 | Dihydrocodeine | 6.4 Strong | 15 |
| 20 | Naltrexone | 5.1 Moderate+ | 15 |
| 21 | Butorphanol | 6.3 Strong | 12 |
| 22 | O-DSMT | 7.7 Intense | 9 |
| 23 | U-47700 | 8.0 Intense | 9 |
| 24 | Glaucine | 3.9 Moderate | 8 |
| 25 | Oxytocin | 5.1 Moderate+ | 8 |
| 26 | AH-7921 | 6.3 Strong | 6 |
| 27 | Doxylamine | 1.4 Threshold | 6 |
| 28 | Acetylfentanyl | 8.4 Intense | 5 |
| 29 | Ethylmorphine | 7.6 Intense | 4 |
| 30 | MT-45 | 6.3 Strong | 4 |
| 31 | Furanylfentanyl | 7.0 Strong+ | 3 |
| 32 | Ketobemidone | 6.3 Strong | 3 |
| 33 | Pentazocine | 5.4 Moderate+ | 3 |
| 34 | 4-Fluorobutyrfentanyl | 6.3 Strong | 2 |
| 35 | Dextropropoxyphene | 6.6 Strong+ | 2 |
| 36 | GABOB | 3.3 Light+ | 2 |
| 37 | Metonitazene | 7.6 Intense | 2 |
| 38 | Bromadol | 3.9 Moderate | 1 |
| 39 | Butyrfentanyl | 3.9 Moderate | 1 |
| 40 | Etodesnitazene | 5.1 Moderate+ | 1 |
| 41 | Salvinorin B Ethoxymethyl Ether | 5.1 Moderate+ | 1 |
| 42 | Tilidine | 5.4 Moderate+ | 1 |
| 43 | 4-Methoxybutyrfentanyl | 7.6 Intense | — |
| 44 | 4Cl-iBF | 7.0 Strong+ | — |
| 45 | 6-MAM | 7.9 Intense | — |
| 46 | 6-MDDM | 5.4 Moderate+ | — |
| 47 | 7-OH | 5.1 Moderate+ | — |
| 48 | Acetorphine | 7.9 Intense | — |
| 49 | Acetyldihydrocodeine | 7.9 Intense | — |
| 50 | Acrylfentanyl | 6.3 Strong | — |
| 51 | Agmatine | 2.4 Light | — |
| 52 | Alfentanil | 6.1 Strong | — |
| 53 | AM-2201 4-methoxynaphthyl analogue | 5.1 Moderate+ | — |
| 54 | AM-7921 | 5.1 Moderate+ | — |
| 55 | Arimistane | 2.0 Light | — |
| 56 | Benzodioxole-Fentanyl | 3.9 Moderate | — |
| 57 | Benzylfentanyl | 5.1 Moderate+ | — |
| 58 | Benzylmorphine | 5.1 Moderate+ | — |
| 59 | Beta-meprodine | 6.0 Strong | — |
| 60 | Bezitramide | 6.4 Strong | — |
| 61 | Carfentanil | 2.6 Light+ | — |
| 62 | Clomethiazole | 4.7 Moderate+ | — |
| 63 | Clonitazene | 5.4 Moderate+ | — |
| 64 | Cychlorphine | 7.0 Strong+ | — |
| 65 | Cyclopentyl-Fentanyl | 3.9 Moderate | — |
| 66 | Desomorphine | 6.6 Strong+ | — |
| 67 | Dextromoramide | 5.4 Moderate+ | — |
| 68 | Dipipanone | 6.3 Strong | — |
| 69 | DPP-26 | 6.3 Strong | — |
| 70 | Etonitazene | 7.9 Intense | — |
| 71 | Glutethimide | 5.4 Moderate+ | — |
| 72 | Hydromorphine | 5.1 Moderate+ | — |
| 73 | Hydroxypethidine | 5.1 Moderate+ | — |
| 74 | IC-26 | 5.4 Moderate+ | — |
| 75 | Imodium | 6.0 Strong | — |
| 76 | Isomethadone | 5.4 Moderate+ | — |
| 77 | Isotonitazene | 7.0 Strong+ | — |
| 78 | Isotonitazepyne | 7.3 Strong+ | — |
| 79 | Levomethorphan | 7.0 Strong+ | — |
| 80 | Lofentanil | 7.0 Strong+ | — |
| 81 | Methoxyacetyl-Fentanyl | 5.4 Moderate+ | — |
| 82 | Methoxypiperamide | 1.9 Light | — |
| 83 | Methyl-dihydro-morphine | 5.1 Moderate+ | — |
| 84 | MGM-15 | 6.6 Strong+ | — |
| 85 | Morpheridine | 3.9 Moderate | — |
| 86 | Morphine-N-oxide | 5.1 Moderate+ | — |
| 87 | N-(2C)-fentanyl | 5.1 Moderate+ | — |
| 88 | N-desethyl Etonitazene | 5.1 Moderate+ | — |
| 89 | N-Desethylisotonitazene | 5.1 Moderate+ | — |
| 90 | NDP | 7.3 Strong+ | — |
| 91 | Nicomorphine | 3.9 Moderate | — |
| 92 | Norcodeine | 5.1 Moderate+ | — |
| 93 | Normorphine | 5.1 Moderate+ | — |
| 94 | Parafluorofentanyl | 3.9 Moderate | — |
| 95 | Phenomorphan | 5.1 Moderate+ | — |
| 96 | Pholcodeine | 5.1 Moderate+ | — |
| 97 | Pronitazene | 6.1 Strong | — |
| 98 | PST | 5.4 Moderate+ | — |
| 99 | Racemorphan | 5.1 Moderate+ | — |
| 100 | Remifentanil | 7.6 Intense | — |
| 101 | Spirochlorphine | 7.9 Intense | — |
| 102 | SR-14968 | 6.3 Strong | — |
| 103 | SR-17018 | 4.7 Moderate+ | — |
| 104 | Sufentanil | 6.7 Strong+ | — |
| 105 | Tetrahydrofuran-Fentanyl | 5.4 Moderate+ | — |
| 106 | U-49900 | 3.9 Moderate | — |
| 107 | U-51754 | 3.9 Moderate | — |
| 108 | Valerylfentanyl | 3.9 Moderate | — |
| 109 | W-15 | 5.0 Moderate+ | — |